La Mesa, CA Commercial Real Estate for Lease and Sale

Explore 50 listings of LA Mesa commercial real estate for lease and for sale to find the best space for your business.

Grossmont Medical Center - Bldg. 3

5565 Grossmont Center Dr., La Mesa, CA
For Lease

Contact for pricing
Property

Office

44,828 SF
Availability

3 Spaces

6,944 SF
Year Built

1970
View Details (opens in new window)
Rancho San Diego Professional Center

3855 Avocado Blvd, Casa de Oro - Mount Helix, La Mesa, CA
For Lease

Contact for pricing
Property

Office

35,916 SF
Availability

1 Space

4,103 SF
Year Built

1983
View Details (opens in new window)
Fletcher Parkway Medical Center

8881 Fletcher Pkwy, La Mesa, CA
For Lease

Contact for pricing
Property

Office

82,024 SF
Availability

4 Spaces

14,553 SF
Year Built

1985
View Details (opens in new window)
Grossmont Medical Center - Bldg. 1

5565 Grossmont Center Dr., La Mesa, CA
For Lease

Contact for pricing
Property

Office

28,632 SF
Availability

1 Space

774 SF
Year Built

1970
View Details (opens in new window)
La Mesa Crossroads

7900 El Cajon Blvd, La Mesa, CA
For Lease

Contact for pricing
Property

Retail

152,364 SF
Availability

1 Space

1,600 SF
Year Built

1981
View Details (opens in new window)
Grossmont Medical Center - Bldg. 2

5565 Grossmont Center Dr., La Mesa, CA
For Lease

Contact for pricing
Property

Office

44,828 SF
Availability

1 Space

2,242 SF
Year Built

1970
View Details (opens in new window)
Allied Plaza

7777 Alvarado Road, La Mesa, CA
For Lease

$30.00 - $37.39/SF/YR
Property

Office

120,000 SF
Availability

8 Spaces

11,458 SF
Year Built

1982
View Details (opens in new window)
Grossmont Center

5500 Grossmont Center Drive, La Mesa, CA
For Lease

Contact for pricing
Property

Retail

1,107,955 SF
Availability

1 Space

5,900 SF
Year Built

1961
View Details (opens in new window)
Grossmont Medical Terrace

8860 Center Drive, La Mesa, CA
For Lease

Contact for pricing
Property

Office

65,000 SF
Availability

1 Space

3,343 SF
Year Built

2007
View Details (opens in new window)
Grossmont Medical Arts Building

8851 Center Drive, La Mesa, CA
For Lease

$21.84/SF/YR
Property

Office

70,222 SF
Availability

2 Spaces

8,108 SF
Year Built

1986
View Details (opens in new window)
Not finding the right space?

Tell us where and what you're looking for and the brokers will come to you
La Mesa Springs

7966 La Mesa Blvd, La Mesa, CA
For Lease

Contact for pricing
Property

Retail

158,993 SF
Availability

1 Space

440 SF
Year Built

1978
View Details (opens in new window)
Plaza La Mesa

7960 University Avenue , La Mesa, CA
For Lease

$1.85/SF/MO
Property

Retail

6,803 SF
Availability

1 Space

3,818 SF
Year Built

1991
View Details (opens in new window)
5811 Amaya Drive
La Mesa Cowork
5811 Amaya Drive #100, La Mesa, CA
Services

Open Workspace

Private Office

Dedicated Desk
Amenities

24/7 security

Complimentary coffee & tea

High-speed internet

Kitchen

Parking

Pet friendly
View Details (opens in new window)
5500 Grossmont Center Drive
The Well
5500 Grossmont Center Drive #195, La Mesa, CA
Services

Open Workspace

Meeting Room
Amenities

Complimentary coffee & tea

High-speed wifi

Privacy booths
View Details (opens in new window)
7317 El Cajon Boulevard
Business Center of La Mesa
7317 El Cajon Boulevard, La Mesa, CA
Services

Virtual Office

Meeting Room

Private Office
Amenities

Catering

Concierge

High-speed internet

High-speed wifi

Mail services

Parking

Receptionist/Secretarial services

Utilities included
View Details (opens in new window)
5480 Baltimore Drive

5480 Baltimore Drive, La Mesa, CA
For Lease

$2.15/SF/MO
Property

Office

3,151 SF
Availability

1 Space

944 SF
View Details (opens in new window)
5345 Timken St

5345 Timken St, La Mesa, CA
For Lease

Contact for pricing
Property

Office

9,213 SF
Availability

6 Spaces

9,155 SF
View Details (opens in new window)
7862 El Cajon Blvd

7862 El Cajon, La Mesa, CA
For Lease

Contact for pricing
Property

Office
Availability

1 Space

7,200 SF
View Details (opens in new window)
6818 El Cajon Boulevard

6818 El Cajon Boulevard, La Mesa, CA
For Lease

$1.95/SF/YR
Property

Retail

930 SF
Availability

1 Space

930 SF
View Details (opens in new window)
6122 Lake Murray Blvd

6122 Lake Murray Blvd, La Mesa, CA
For Sale

$4,995,000
Property

Retail

10,800 SF
Year Built

1979
View Details (opens in new window)
5575 Baltimore Dr

5575 Baltimore Dr, La Mesa, CA
For Lease

$2.25 - $2.40/SF/MO
Property

Retail

12,064 SF
Availability

2 Spaces

3,003 SF
Year Built

1986
View Details (opens in new window)
Baltimore West Shopping Center

5260 - 5316 Baltimore Drive, La Mesa, CA
For Lease

Contact for pricing
Property

Retail

10,400 SF
Availability

4 Spaces

10,396 SF
View Details (opens in new window)
La Mesa Medical/Professional Office Suites

8911 La Mesa Blvd, La Mesa, CA
For Lease

Contact for pricing
Property

Other
Availability

1 Space

2,200 SF
View Details (opens in new window)
Jackson Square

5202-5230 Jackson Dr, La Mesa, CA
For Lease

$2.25/SF/MO
Property

Retail

16,664 SF
Availability

2 Spaces

4,500 SF
Year Built

1982
View Details (opens in new window)
4730 Palm Avenue
The Hot Suite
4730 Palm Avenue #206B, La Mesa, CA
Services

Virtual Office

Private Office
Amenities

Complimentary coffee & tea

High-speed wifi

Mail services

White boards
View Details (opens in new window)
8110 Commercial St

8110 Commercial St, La Mesa, CA
For Lease

Contact for pricing
Property

Industrial

3,426 SF
Availability

1 Space

3,426 SF
Year Built

1950
View Details (opens in new window)

Frequently Asked Questions

Commercial real estate is a broad category that includes a high variety of space types designed to meet the needs of various industries of the local economy and their specialized subsectors, as presented in our real estate 101 guide to types of commercial real estate. However, there are three main categories that you are most likely to come across: office, retail, and industrial space.

Modern office space is typically organized over large floor plates bound by high ceilings and large windows for an abundance of natural light and is located in transit-oriented developments with good access to multiple modes of transportation, so as to facilitate employee commute. The LA Mesa commercial real estate market incorporates 598,517 square feet of office space across 23 buildings.

Office buildings can also accommodate coworking spaces, which are shared office options that typically cater to the needs of small, startup businesses that require flexible workspaces, a concentration of amenities, and services that can be accessed on an occasional or short-term basis.
Retail space includes shopping malls, department stores, street retail, or specialty stores dedicated to a narrow range of products. Such properties are typically located in high foot-traffic and/or car traffic areas, to facilitate customer access. The LA Mesa commercial real estate market includes 1,761,179 square feet of retail space in a variety of settings.
Industrial property most often serves businesses operating in manufacturing or logistics and generally consists of large open spaces located within good access to roads, railways, freight airports or regional water ports. Industrial space listings can include warehouses, manufacturing plants, distribution centers, flexible industrial space, or even data center facilities. Across the LA Mesa market, there is a total of 3,426 square feet of industrial property.

The listing inventory in LA Mesa incorporates commercial real estate for lease and for sale of almost all property types and subtypes. However, you’ll find some categories offer more rental or investment opportunities than others.

The largest share of commercial real estate space for lease in LA Mesa is represented by Office space, which accounts for 123,927 square feet of available listings. Retail space available in LA Mesa adds up to 101,170 square feet.

Meanwhile, most of the listings of commercial property for sale in LA Mesa are in the Retail category.

The price of renting or buying commercial real estate is influenced by a variety of factors, including: the property type (for example, office space is priced higher than other property types in most locations); the condition and asset class rating (property rated class A or above will typically command a higher price than lower grade classifications); the quality or the development potential of the property location; whether or not there is high demand for the type of commercial asset in question; and what the state of supply is relative to demand.

The average rent for commercial real estate space listed for lease in LA Mesa is $28.97 per square foot. However, this value does not offer enough perspective on its own, as you will find significant variation in prices across property types, property classes, and location, as well as other impacting factors. For instance, rent per square foot of office space in LA Mesa can vary greatly depending on the rating of the property from Class A to Class C, as well as across the city depending on the location of the asset.

Whether you are looking for commercial real estate for lease or commercial property for sale, the best choice of location depends on the factors that are most relevant to your business strategy. A good thing to look for at the start, however, is the areas of the city that have the highest concentration of your preferred type of property, as these areas are generally well connected to the amenities and points of interest that are most relevant to each property type.

As such, there are several areas that you could consider to be the best location for commercial real estate in LA Mesa, depending on the property type you are interested in.

Select your preferred property type from the search filters menu at the top of the search page and then navigate the interactive map for a better view of commercial real estate availability in the locations most suited to your needs.

Regardless of whether buying or leasing commercial space is a new experience for you, there are significant benefits to working with a commercial real estate broker. In addition to saving you time and money, an experienced broker will contribute specialist knowledge of the local market, the property type you need representation for, and will handle negotiations on your behalf in your best interest.

To start, it is important for you to have a good understanding of what kind of broker you need. For instance, there are differences between a tenant broker and a listing broker. Also important at the start is to have a clear idea of what kind of space (or tenant) you are looking for and what (if any) particular needs and requirements you might have. And, while it is good to get a referral, you should interview several brokers to better gauge who you feel would best represent your interests.

CommercialCafe hosts listings from some of the most trusted commercial real estate brokerages in the country. Use the contact form available on each listing page or the contact details for the property representatives to reach out and start your search!

The profitability of a commercial real estate investment depends on a multitude of factors working together. These factors include the quality of the asset itself — which itself includes aspects such as location, property class, amenities, and the quality of the property management — to the local market conditions, the state of the local economy, the demand for that particular type of commercial property, and of course the costs of owning and maintaining it relative to what leasing rate or sale price you get from the property. Asking rents in the city went as high as $37.39 per square foot. In particular, the property type commanding the highest lease rates in LA Mesa was Office space.

Conversely, the highest sale price last year was $8,675,000 that is located at 4700 Spring Street.

The average size of a commercial property in LA Mesa depends greatly on the property type and the location — geographical possibilities and zoning allowances have significant influence on how big developers can build. While there are outliers that break height or volume records in the city, we can look at some average sizes by property use:

In LA Mesa, the average size of an office property is 31,501 square feet.
Retail properties here incorporate an average of 88,059 square feet.
Industrial space in LA Mesa is in buildings that are, on average 3,426 square feet in size.

La Mesa, CA Currently Available Listings

Commercial Space for Lease Breakdown

Commercial real estate listings for rent in LA Mesa currently add up to 232,613 square feet. The market offers 21 active office listing(s), which amount to 123,927 square feet and account for 51% of commercial spaces on the market. Local retail availability includes 101,170 square feet across 17 retail space(s). Industrial space for rent opportunities in LA Mesa amount to 3,426 square feet across a total of 1 warehouse and other industrial listing(s).

Property Type	Count of Listings	Total SF
Office	21	123,927
Retail	17	101,170
Industrial	1	3,426
Other	2	4,090

Commercial Space for Sale Breakdown

What’s more, if you are interested in making an investment in the local market, you can also find commercial real estate for sale in La Mesa, CA. Currently, there is 72,863 square feet of commercial property for sale here , which includes 2 office building(s) for sale , 3 retail investment opportunity listing(s) .

Property Type	Count of Listings	Total SF
Office	2	15,223
Retail	3	35,310
Other	3	22,330

La Mesa, CA Commercial Real Estate for Lease and Sale

Grossmont Medical Center - Bldg. 3

Rancho San Diego Professional Center

Fletcher Parkway Medical Center

Grossmont Medical Center - Bldg. 1

La Mesa Crossroads

Grossmont Medical Center - Bldg. 2

Allied Plaza

Grossmont Center

Grossmont Medical Terrace

Grossmont Medical Arts Building

La Mesa Springs

Plaza La Mesa

5811 Amaya Drive

5500 Grossmont Center Drive

7317 El Cajon Boulevard

5480 Baltimore Drive

5345 Timken St

7862 El Cajon Blvd

6818 El Cajon Boulevard

6122 Lake Murray Blvd

5575 Baltimore Dr

Baltimore West Shopping Center

La Mesa Medical/Professional Office Suites

Jackson Square

4730 Palm Avenue

8110 Commercial St

Frequently Asked Questions

La Mesa, CA Currently Available Listings

Commercial Space for Lease Breakdown

Commercial Space for Sale Breakdown

Other Popular Searches

Popular Coworking Searches

Popular Office Searches

Popular Retail Searches

Popular Industrial Searches

About us

About Us

Our Tools

La Mesa, CA Commercial Real Estate for Lease and Sale

Frequently Asked Questions

What are the different types of commercial real estate?

What types of commercial real estate are available in LA Mesa, CA?

What factors affect the price of commercial real estate in LA Mesa, CA?

What is the average rent for commercial space in LA Mesa, CA?

What are the best areas for commercial real estate in LA Mesa, CA?

How do I find a good commercial real estate broker?

What is the most profitable commercial real estate?

What is the average size of a commercial property in LA Mesa, CA?

La Mesa, CA Currently Available Listings

Commercial Space for Lease Breakdown

Commercial Space for Sale Breakdown

Other Popular Searches

Popular Coworking Searches

Popular Office Searches

Popular Retail Searches

Popular Industrial Searches

About us