Portsmouth, NH Commercial Real Estate for Lease and Sale

Explore 48 listings of Portsmouth commercial real estate for lease and for sale to find the best space for your business.

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4 Greenleaf Woods Drive- offices

4 Greenleaf Woods Drive, Elwyn Park, Portsmouth, NH
Property

Office

100 SF
Availability

1 Space

1,418 SF
Year Built

1987
For Lease

$1,990.00/MO
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Residential Lot - Portsmouth, NH

Marjorie Street, Elwyn Park, Portsmouth, NH
Property

VacantLand
For Sale

$279,900
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100 Market Street

100 Market Street, North Mill Pond, Portsmouth, NH
Property

Office

57,455 SF
Availability

6 Spaces

16,685 SF
Year Built

1999
For Lease

$29.00/SF/YR
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172 Hanover Street

172 Hanover Street, North Mill Pond, Portsmouth, NH
Property

Office

12,523 SF
Availability

1 Space

1,500 SF
Year Built

1850
For Lease

$22.00/SF/YR
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273 Corporate Drive

273 Corporate Drive, Sherburne, Portsmouth, NH
Property

Office

100,000 SF
Availability

1 Space

16,027 SF
Year Built

2001
For Lease

$19.50/SF/YR
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Portsmouth Office Park - 230 Commerce Way

230 Commerce Way, Wentworth Acres, Portsmouth, NH
Property

Office

50,400 SF
Availability

1 Space

4,930 SF
Year Built

1997
For Lease

$18.50/SF/YR
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360 Corporate Drive, Portsmouth, NH

360 Corporate Drive, Sherburne, Portsmouth, NH
Property

Office

52,000 SF
Availability

3 Spaces

42,001 SF
Year Built

2025
For Lease

$38.00/SF/YR
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145 Maplewood Avenue

145 Maplewood Avenue, North Mill Pond, Portsmouth, NH
Property

Office

73,731 SF
Availability

3 Spaces

12,802 SF
Year Built

2021
For Lease

$37.00/SF/YR
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111 New Hampshire Avenue

111 New Hampshire Avenue, Sherburne, Portsmouth, NH
Property

Office

74,134 SF
Availability

1 Space

56,488 SF
Year Built

2007
For Lease

$11.95 - $14.00/SF/YR
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5 Greenleaf Woods Drive

5 Greenleaf Woods Drive, Elwyn Park, Portsmouth, NH
Property

Office

720 SF
Availability

1 Space

720 SF
Year Built

1987
For Lease

$1,400.00/MO
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125 Aviation Avenue, Portsmouth, NH

125 Aviation Ave, Sherburne, Portsmouth, NH
Property

Office

65,212 SF
Availability

1 Space

5,320 SF
Year Built

1998
For Lease

$5,000.00/MO
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Orchard Park

875 Greenland Road, Meadowbrook, Portsmouth, NH
Property

Office

46,098 SF
Availability

1 Space

2,500 SF
Year Built

1985
For Lease

$12.00/SF/YR
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Portsmouth Office Park - 210 Commerce Way

210 Commerce Way, Wentworth Acres, Portsmouth, NH
Property

Office

50,400 SF
Availability

2 Spaces

5,026 SF
Year Built

1989
For Lease

$19.50/SF/YR
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100 Borthwick Avenue

100 Borthwick Avenue, Meadowbrook, Portsmouth, NH
Property

Office

47,745 SF
Year Built

1978
For Sale

$11,000,000
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375 Banfield Road, Portsmouth, NH

375 Banfield Rd, Elwyn Park, Portsmouth, NH
Property

Industrial

75,000 SF
Availability

1 Space

75,000 SF
Year Built

2024
For Lease

$15.00/SF/YR
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Griffin Park Medical Office Condominium

200 Griffin Rd, Portsmouth Plains, Portsmouth, NH
Property

Other
Availability

1 Space

2,998 SF
Year Built

2004
For Lease

$20.00/SF/YR
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215 Commerce Way

215 Commerce Way, Wentworth Acres, Portsmouth, NH
Property

Office

40,000 SF
Availability

1 Space

12,336 SF
Year Built

1990
For Lease

$16.50/SF/YR
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Portsmouth
Regus
170 Commerce Way Suite 200, Portsmouth, NH
Services

Virtual Office

Open Workspace

Private Office

Dedicated Desk
Amenities

24/7 security

Access to global network

Business address

Business lounge

Cleaning services

Ergonomic furniture

Lounge area

Mail services

Money-back guarantee

Office furniture
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40 Pleasant Street (Small Office Suite)

40 Pleasant Street (Second Floor), Haymarket Square, Portsmouth, NH
Property

Office

21,924 SF
Availability

1 Space

587 SF
Year Built

1860
For Lease

$30.00/SF/YR
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10 Commercial Aly

10 Commercial Aly, North Mill Pond, Portsmouth, NH
Property

Office

6,251 SF
Availability

1 Space

1,869 SF
Year Built

2007
For Lease

$28.89/SF/YR
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40 Pleasant St

40 Pleasant St, Haymarket Square, Portsmouth, NH
Property

Office

16,994 SF
Year Built

1860
For Sale

$5,790,000
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4 Cutts, Unit 4

4 Cutts, Unit 4, Downtown Portsmouth, Portsmouth, NH
Property

Industrial

66,887 SF
Availability

1 Space

16,500 SF
Year Built

1950
For Lease

$8.41/SF/YR
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426 Middle Street

426 Middle Street, Downtown Portsmouth, Portsmouth, NH
Property

Office

640 SF
Availability

1 Space

640 SF
Year Built

1830
For Lease

$1,850.00/MO
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Jackson Gray Building

330 Borthwick Avenue, Meadowbrook, Portsmouth, NH
Property

Office

55,200 SF
Availability

1 Space

6,366 SF
Year Built

1986
For Lease

$19.75/SF/YR
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Pease International Tradeport

325 Corporate Drive, Sherburne, Portsmouth, NH
Property

Office

100,928 SF
Availability

1 Space

100,928 SF
Year Built

2001
For Lease

$17.75/SF/YR
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865 Islington Street, Portsmouth, NH

865 Islington St, North Mill Pond, Portsmouth, NH
Property

Retail

3,154 SF
Availability

1 Space

3,154 SF
Year Built

1880
For Lease

$23.00/SF/YR
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Frequently Asked Questions

Commercial real estate is a broad category that includes a high variety of space types designed to meet the needs of various industries of the local economy and their specialized subsectors, as presented in our real estate 101 guide to types of commercial real estate. However, there are three main categories that you are most likely to come across: office, retail, and industrial space.

Modern office space is typically organized over large floor plates bound by high ceilings and large windows for an abundance of natural light and is located in transit-oriented developments with good access to multiple modes of transportation, so as to facilitate employee commute. The Portsmouth commercial real estate market incorporates 964,338 square feet of office space across 30 buildings.

Office buildings can also accommodate coworking spaces, which are shared office options that typically cater to the needs of small, startup businesses that require flexible workspaces, a concentration of amenities, and services that can be accessed on an occasional or short-term basis.
Retail space includes shopping malls, department stores, street retail, or specialty stores dedicated to a narrow range of products. Such properties are typically located in high foot-traffic and/or car traffic areas, to facilitate customer access. The Portsmouth commercial real estate market includes 329,731 square feet of retail space in a variety of settings.
Industrial property most often serves businesses operating in manufacturing or logistics and generally consists of large open spaces located within good access to roads, railways, freight airports or regional water ports. Industrial space listings can include warehouses, manufacturing plants, distribution centers, flexible industrial space, or even data center facilities. Across the Portsmouth market, there is a total of 222,526 square feet of industrial property.

The listing inventory in Portsmouth incorporates commercial real estate for lease and for sale of almost all property types and subtypes. However, you’ll find some categories offer more rental or investment opportunities than others.

The largest share of commercial real estate space for lease in Portsmouth is represented by Office space, which accounts for 262,831 square feet of available listings. Industrial space available in Portsmouth adds up to 175,443 square feet.

Meanwhile, most of the listings of commercial property for sale in Portsmouth are in the Office category.

The price of renting or buying commercial real estate is influenced by a variety of factors, including: the property type (for example, office space is priced higher than other property types in most locations); the condition and asset class rating (property rated class A or above will typically command a higher price than lower grade classifications); the quality or the development potential of the property location; whether or not there is high demand for the type of commercial asset in question; and what the state of supply is relative to demand.

The average rent for commercial real estate space listed for lease in Portsmouth is $20.2 per square foot. However, this value does not offer enough perspective on its own, as you will find significant variation in prices across property types, property classes, and location, as well as other impacting factors. For instance, rent per square foot of office space in Portsmouth can vary greatly depending on the rating of the property from Class A to Class C, as well as across the city depending on the location of the asset.

Whether you are looking for commercial real estate for lease or commercial property for sale, the best choice of location depends on the factors that are most relevant to your business strategy. A good thing to look for at the start, however, is the areas of the city that have the highest concentration of your preferred type of property, as these areas are generally well connected to the amenities and points of interest that are most relevant to each property type.

As such, there are several areas that you could consider to be the best location for commercial real estate in Portsmouth, depending on the property type you are interested in. The highest concentration of commercial space listings of any kind in Portsmouth is in the North Mill Pond neighborhood. But if we look at each commercial property type, we find that for office space, the best location is the North Mill Pond area.

Meanwhile, retail space opportunities are most abundant in the North Mill Pond submarket. Alternatively, if you are looking for warehouse or other industrial space, consider looking at listings in Sherburne.

Select your preferred property type from the search filters menu at the top of the search page and then navigate the interactive map for a better view of commercial real estate availability in the locations most suited to your needs.

Regardless of whether buying or leasing commercial space is a new experience for you, there are significant benefits to working with a commercial real estate broker. In addition to saving you time and money, an experienced broker will contribute specialist knowledge of the local market, the property type you need representation for, and will handle negotiations on your behalf in your best interest.

To start, it is important for you to have a good understanding of what kind of broker you need. For instance, there are differences between a tenant broker and a listing broker. Also important at the start is to have a clear idea of what kind of space (or tenant) you are looking for and what (if any) particular needs and requirements you might have. And, while it is good to get a referral, you should interview several brokers to better gauge who you feel would best represent your interests.

CommercialCafe hosts listings from some of the most trusted commercial real estate brokerages in the country. Use the contact form available on each listing page or the contact details for the property representatives to reach out and start your search!

The profitability of a commercial real estate investment depends on a multitude of factors working together. These factors include the quality of the asset itself — which itself includes aspects such as location, property class, amenities, and the quality of the property management — to the local market conditions, the state of the local economy, the demand for that particular type of commercial property, and of course the costs of owning and maintaining it relative to what leasing rate or sale price you get from the property. Asking rents in the city went as high as $30 per square foot. In particular, the property type commanding the highest lease rates in Portsmouth was Office space.

Conversely, the highest sale price last year was $6,150,000 that is located at 111 New Hampshire Avenue.

The average size of a commercial property in Portsmouth depends greatly on the property type and the location — geographical possibilities and zoning allowances have significant influence on how big developers can build. While there are outliers that break height or volume records in the city, we can look at some average sizes by property use:

In Portsmouth, the average size of an office property is 41,928 square feet.
Retail properties here incorporate an average of 65,947 square feet.
Industrial space in Portsmouth is in buildings that are, on average 55,632 square feet in size.

Portsmouth, NH Currently Available Listings

Commercial Space for Lease Breakdown

Commercial real estate listings for rent in Portsmouth currently add up to 527,812 square feet. The market offers 27 active office listing(s), which amount to 262,831 square feet and account for 71% of commercial spaces on the market. Local retail availability includes 89,538 square feet across 5 retail space(s). Industrial space for rent opportunities in Portsmouth amount to 175,443 square feet across a total of 6 warehouse and other industrial listing(s).

Property Type	Count of Listings	Total SF
Office	27	262,831
Retail	5	89,538
Industrial	6	175,443

Commercial Space for Sale Breakdown

What’s more, if you are interested in making an investment in the local market, you can also find commercial real estate for sale in Portsmouth, NH. Currently, there is 92,476 square feet of commercial property for sale here , which includes 2 office building(s) for sale , 1 retail investment opportunity listing(s) .

Property Type	Count of Listings	Total SF
Office	2	64,739
Retail	1	27,737

Portsmouth, NH Commercial Real Estate for Lease and Sale

4 Greenleaf Woods Drive- offices

Residential Lot - Portsmouth, NH

100 Market Street

172 Hanover Street

273 Corporate Drive

Portsmouth Office Park - 230 Commerce Way

360 Corporate Drive, Portsmouth, NH

145 Maplewood Avenue

111 New Hampshire Avenue

5 Greenleaf Woods Drive

125 Aviation Avenue, Portsmouth, NH

Orchard Park

Portsmouth Office Park - 210 Commerce Way

100 Borthwick Avenue

375 Banfield Road, Portsmouth, NH

Griffin Park Medical Office Condominium

215 Commerce Way

Portsmouth

40 Pleasant Street (Small Office Suite)

10 Commercial Aly

40 Pleasant St

4 Cutts, Unit 4

426 Middle Street

Jackson Gray Building

Pease International Tradeport

865 Islington Street, Portsmouth, NH

Frequently Asked Questions

Portsmouth, NH Currently Available Listings

Commercial Space for Lease Breakdown

Commercial Space for Sale Breakdown

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Portsmouth, NH Commercial Real Estate for Lease and Sale

Frequently Asked Questions

What are the different types of commercial real estate?

What types of commercial real estate are available in Portsmouth, NH?

What factors affect the price of commercial real estate in Portsmouth, NH?

What is the average rent for commercial space in Portsmouth, NH?

What are the best areas for commercial real estate in Portsmouth, NH?

How do I find a good commercial real estate broker?

What is the most profitable commercial real estate?

What is the average size of a commercial property in Portsmouth, NH?

Portsmouth, NH Currently Available Listings

Commercial Space for Lease Breakdown

Commercial Space for Sale Breakdown

Other Popular Searches

Popular Coworking Searches

Popular Office Searches

Popular Retail Searches

Popular Industrial Searches

About us