39 Office Spaces for Rent in La Mesa, CA

Find the best La Mesa, CA office space among 39 for rent listings currently on the market.

Rancho San Diego Professional Center

3855 Avocado Blvd, Casa de Oro - Mount Helix, La Mesa, CA
Property

Office

35,916 SF
Availability

1 Space

4,103 SF
Year Built

1983
For Lease Contact for pricing
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Grossmont Medical Terrace

8860 Center Drive, La Mesa, CA
Property

Office

65,000 SF
Availability

1 Space

3,343 SF
Year Built

2007
For Lease Contact for pricing
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Allied Plaza

7777 Alvarado Road, La Mesa, CA
Property

Office

120,000 SF
Availability

9 Spaces

12,749 SF
Year Built

1982
For Lease

$30.00 - $37.39/SF/YR
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Grossmont Medical Center - Bldg. 3

5565 Grossmont Center Dr., La Mesa, CA
Property

Office

44,828 SF
Availability

3 Spaces

6,944 SF
Year Built

1970
For Lease Contact for pricing
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Grossmont Medical Center - Bldg. 1

5565 Grossmont Center Dr., La Mesa, CA
Property

Office

28,632 SF
Availability

1 Space

774 SF
Year Built

1970
For Lease Contact for pricing
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Grossmont Medical Arts Building

8851 Center Drive, La Mesa, CA
Property

Office

70,222 SF
Availability

2 Spaces

8,108 SF
Year Built

1986
For Lease

$21.84/SF/YR
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Grossmont Medical Center - Bldg. 2

5565 Grossmont Center Dr., La Mesa, CA
Property

Office

44,828 SF
Availability

1 Space

2,242 SF
Year Built

1970
For Lease Contact for pricing
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Fletcher Parkway Medical Center

8881 Fletcher Pkwy, La Mesa, CA
Property

Office

82,024 SF
Availability

4 Spaces

14,553 SF
Year Built

1985
For Lease Contact for pricing
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5811 Amaya Drive
La Mesa Cowork
5811 Amaya Drive #100, La Mesa, CA
Services

Open Workspace

Private Office

Dedicated Desk
Amenities

24/7 security

Complimentary coffee & tea

High-speed internet

Kitchen

Parking

Pet friendly
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5500 Grossmont Center Drive
The Well
5500 Grossmont Center Drive #195, La Mesa, CA
Services

Open Workspace

Meeting Room
Amenities

Complimentary coffee & tea

High-speed wifi

Privacy booths
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7317 El Cajon Boulevard
Business Center of La Mesa
7317 El Cajon Boulevard, La Mesa, CA
Services

Virtual Office

Meeting Room

Private Office
Amenities

Catering

Concierge

High-speed internet

High-speed wifi

Mail services

Parking

Receptionist/Secretarial services

Utilities included
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4730 Palm Avenue
The Hot Suite
4730 Palm Avenue #206B, La Mesa, CA
Services

Virtual Office

Private Office
Amenities

Complimentary coffee & tea

High-speed wifi

Mail services

White boards
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7862 El Cajon Blvd

7862 El Cajon, La Mesa, CA
Property

Office
Availability

1 Space

7,200 SF
For Lease Contact for pricing
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7472 - 7474 El Cajon Blvd

7472 - 7474 El Cajon Blvd, La Mesa, CA
Property

Office

11,880 SF
Availability

1 Space

11,880 SF
Year Built

1979
For Lease

$1.85/SF/YR
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La Mesa Village

8270 La Mesa Blvd, La Mesa, CA
Property

Office

3,167 SF
Availability

1 Space

3,167 SF
For Lease

$2.50/SF/YR
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7960 University Avenue

7960 University Avenue, La Mesa, CA
Property

Retail

2,985 SF
Availability

1 Space

2,092 SF
For Lease

$1.80/SF/MO
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Lake Park Plaza

5575 Lake Park Way, La Mesa, CA
Property

Office

4,141 SF
Availability

1 Space

1,557 SF
Year Built

1989
For Lease

$2.39/SF/MO
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6818 El Cajon Boulevard

6818 El Cajon Boulevard, La Mesa, CA
Property

Retail

930 SF
Availability

1 Space

930 SF
For Lease

$1.95/SF/YR
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5345 Timken St

5345 Timken St, La Mesa, CA
Property

Office

9,213 SF
Availability

6 Spaces

9,155 SF
For Lease Contact for pricing
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8374-8376 Hercules St

8374-8376 Hercules St, La Mesa, CA
Property

Office

12,000 SF
Availability

1 Space

12,000 SF
Year Built

1967
For Lease Contact for pricing
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Jackson Square

5202-5230 Jackson Dr, La Mesa, CA
Property

Retail

16,664 SF
Availability

2 Spaces

4,500 SF
Year Built

1982
For Lease

$2.25/SF/MO
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7853 El Cajon Blvd

7853 El Cajon Blvd, La Mesa, CA
Property

Office

10,159 SF
Availability

2 Spaces

1,023 SF
For Lease

$950.00 - $995.00/MO
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5480 Baltimore Drive

5480 Baltimore Drive, La Mesa, CA
Property

Office

3,151 SF
Availability

1 Space

944 SF
For Lease

$2.15/SF/MO
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SAICO Building

7863 La Mesa Blvd., La Mesa, CA
Property

Office

15,300 SF
Availability

1 Space

2,643 SF
Year Built

1987
For Lease

$30.00/SF/YR
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Frequently Asked Questions

Asking prices vary based on the property location, rating, amenities such as proximity to restaurants, cafes, and entertainment venues, as well as convenience of access to public transport, airports, and thoroughfares.

The minimum rental rate for office space in LA Mesa is $21.84 per square foot. Among listings of office space currently available for lease in LA Mesa, the maximum rental rate is $37.39 per square foot.

Most experts recommend an average of between 75 and 150 square feet of office space per person. However, it is important to keep in mind that how much office space you ultimately need depends on your activity and how you need to use the space, as much as it does on how many people it should accommodate. If you already know what size office would best suit your needs, use the available space size filter at the top of the search page to focus your search on the best fit for you.

You’ll find a home for almost any size of business in LA Mesa, as the local office market offers a wide range of options. Office spaces currently on the market go up to as much as 12,000 square feet in size for an individual listing.
However, there is a variety of differently sized opportunities below that maximum. For your consideration, the median size of an office space for lease in LA Mesa is 1,855 square feet, and the average office space size here is 3,260 square feet.

You can find 39 office listing(s) for lease in LA Mesa, which add up to a total of 123,927 square feet. Availability on the market includes a variety of office use types, such as Medical Office, General Office, Flex - Office.

The most common office use type currently available for lease in LA Mesa is Medical Office, which is offered in 13 or 33.33% of listings. The second-most frequent office use type listed here is General Office, which account for 13 or 33.33% of office space currently available.

You can search 2 office sublease listing(s) in LA Mesa, which amount to a total of 5,455 square feet. Sublease opportunities on the market include Medical Office, General Office, Flex - Office.

The best choice of neighborhood for your office space will greatly depend on the elements that are most relevant to your business and your employees. However, a good criterion to start with is to look at the areas of the city that have the highest concentration of office properties, as these areas are generally well connected to transit options and have a good degree of amenity availability.

Each individual’s commuting experience will of course be different depending on a number of factors. Check the location description details for the office listings that catch your eye, to get an overview of walkability, access to public transport, the quality of infrastructure dedicated to biking commuters, as well as the proximity to parking facilities, fuel stations, and other essential amenities.

The LA Mesa office market incorporates a mix of properties of various ages, ratings, construction grades, and other quality indicators. Roughly 12.82% of total office space listings in the city are in properties rated Class A. Class B office space accounts for 61.54% of spaces listed on the leasing market. Class C office space makes up 2.56% of office space available in LA Mesa.

Buildings completed in and since the year 2000 account for 4.76% of office properties in the city and incorporate a total of 65,000 square feet. About 9.52% of office space in LA Mesa is in buildings that have been renovated at least once since 2000.

There are, of course, a lot of things to factor in when you are looking for office space. Aspects including the accessibility of the location, the quality of the facility, the size of the space, the convenience of nearby amenities, the type and duration of the lease, and of course the cost are all part of the search and decision process. For a quick checklist of what you should take into account when researching the market, consider these seven tips for choosing the best office location for your business. Alternatively, for a comprehensive take on everything to consider when looking for office space, see our in-depth guide to finding office space for small or growing companies. The guide also includes insights from seasoned professionals and can serve as a helpful resource for growing companies, no matter their current size.

Are you looking to lease office space in the vicinity of your current location or in a particular neighborhood of LA Mesa? Using the interactive map, you can easily navigate to your preferred location and customize your search area around a specific point of interest. Select “Radius” from the Search Mode options menu, click on the map to set your search reference point, and expand the radius to select your desired search area. Browse available listings to find the best office space that meets your location, as well as other business needs.

La Mesa, CA Office Inventory Breakdown

There are a number of factors that make a city attractive for businesses to relocate or expand, as well as for investors to enhance their portfolios through local acquisitions. Among the most important factors to consider are the size and quality of the local office market, which is an essential component of the local economy.

Total Office Space in LA Mesa: 954,981 Sq. Ft.

In 2024 the LA Mesa office market encompassed 954,981 square feet of space.

LA Mesa Office Market Breakdown by Building Size
Building Size Range	Total Square Feet	Share of Total Office
50k to 100k Sq. Ft.	303,933 Sq. Ft.	31.83%
100k to 500k Sq. Ft.	332,487 Sq. Ft.	34.82%

LA Mesa Office Market Breakdown by Building Quality Rating
Class	Total Square Feet	Share of Total Office
Class B	954,981 Sq. Ft.	100%

Data was provided by CommercialEdge, refers to properties larger than 50,000 square feet.

39 Office Spaces for Rent in La Mesa, CA

Rancho San Diego Professional Center

Grossmont Medical Terrace

Allied Plaza

Grossmont Medical Center - Bldg. 3

Grossmont Medical Center - Bldg. 1

Grossmont Medical Arts Building

Grossmont Medical Center - Bldg. 2

Fletcher Parkway Medical Center

5811 Amaya Drive

5500 Grossmont Center Drive

7317 El Cajon Boulevard

4730 Palm Avenue

7862 El Cajon Blvd

7472 - 7474 El Cajon Blvd

La Mesa Village

7960 University Avenue

Lake Park Plaza

6818 El Cajon Boulevard

5345 Timken St

8374-8376 Hercules St

Jackson Square

7853 El Cajon Blvd

5480 Baltimore Drive

SAICO Building

Frequently Asked Questions

La Mesa, CA Office Inventory Breakdown

Total Office Space in LA Mesa: 954,981 Sq. Ft.

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39 Office Spaces for Rent in La Mesa, CA

Frequently Asked Questions

How much does office space cost in LA Mesa, CA?

How much office space do I need?

What types of office space can I lease in LA Mesa, CA?

Can I find sublease office space in LA Mesa, CA?

Where is the best location for office space in LA Mesa, CA?

How long is the average commute to work in LA Mesa, CA?

Where can I find the highest quality office space in LA Mesa, CA?

How do I find the best office space in LA Mesa, CA?

How can I find office space for rent near me?

La Mesa, CA Office Inventory Breakdown

Total Office Space in LA Mesa: 954,981 Sq. Ft.

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Popular Coworking Searches

About us