1 Office Space for Rent in Otay Mesa, San Diego, CA

Find the best Otay Mesa, San Diego, CA office space among 1 for rent listings currently on the market.

Empire Centre

7880 & 7920 Airway Rd, Otay Mesa, San Diego, CA
For Lease

$1.20 - $2.50/SF/MO
Property

Industrial

66,413 SF
Availability

2 Spaces

15,076 SF
Year Built

1999
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We found 5 properties within a 5-mile radius of Otay Mesa

Millenia Office - Think - Building I

SEC Millenia Avenue & Stylus Street, Otay Ranch, Chula Vista, CA
For Lease

Contact for pricing
Property

Office

150,000 SF
Availability

4 Spaces

150,000 SF
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Millenia Office - Think - Building II

1785 Millenia Avenue, Otay Ranch, Chula Vista, CA
For Lease

Contact for pricing
Property

Office

168,000 SF
Availability

5 Spaces

168,000 SF
Year Built

2025
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Avalyn

1774 Metro Avenue Chula Vista, Otay Ranch, Chula Vista, CA
For Lease

Contact for pricing
Property

Retail

16,000 SF
Availability

4 Spaces

4,923 SF
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1750 East Palomar Street

1750 East Palomar Street, Otay Ranch, Chula Vista, CA
For Lease

Contact for pricing
Property

Retail

1,573 SF
Availability

1 Space

1,573 SF
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IOS Offices Via Corporativo
IOS Offices
Misión de San Javier 10643, Tijuana, B.C.
Services

Meeting Room

Private Office

Dedicated Desk
Amenities

Complimentary coffee & tea

Kitchen

Lounge area

Printer

Safe Spaces™
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Otay Mesa, San Diego, CA Office Inventory Breakdown

There are a number of factors that make a city attractive for businesses to relocate or expand, as well as for investors to enhance their portfolios through local acquisitions. Among the most important factors to consider are the size and quality of the local office market, which is an essential component of the local economy.

Total Office Space in San Diego: 279,147 Sq. Ft.

In 2024 the San Diego office market encompassed 279,147 square feet of space.

San Diego Office Market Breakdown by Building Size
Building Size Range	Total Square Feet	Share of Total Office
50k to 100k Sq. Ft.	105,762 Sq. Ft.	37.89%
100k to 500k Sq. Ft.	107,000 Sq. Ft.	38.33%

San Diego Office Market Breakdown by Building Quality Rating
Class	Total Square Feet	Share of Total Office
Class B	172,147 Sq. Ft.	61.67%
Class C	107,000 Sq. Ft.	38.33%

Data was provided by CommercialEdge, refers to properties larger than 50,000 square feet.

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CommercialCafe is your go-to commercial real estate listing source. We partner with highly respected major brokerages from across the country to ensure high-quality listings that are updated frequently. Our online marketplace lists all commercial property types from office, coworking, retail, and industrial to special purpose properties.

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1 Office Space for Rent in Otay Mesa, San Diego, CA

Empire Centre

We found 5 properties within a 5-mile radius of Otay Mesa

Millenia Office - Think - Building I

Millenia Office - Think - Building II

Avalyn

1750 East Palomar Street

IOS Offices Via Corporativo

Otay Mesa, San Diego, CA Office Inventory Breakdown

Total Office Space in San Diego: 279,147 Sq. Ft.

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