39 Office Spaces for Rent in San Bruno, CA

Find the best San Bruno, CA office space among 39 for rent listings currently on the market.

San Bruno Medical Office Building

1001 Sneath Lane, San Bruno, CA
Property

Office

32,658 SF
Availability

2 Spaces

4,407 SF
For Lease

$38.00/SF/YR
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365 South Spruce Avenue

365 S Spruce Ave, Lindenville, South San Francisco, CA
Property

Office

5,952 SF
Availability

1 Space

3,000 SF
Year Built

1998
For Lease

$3.00/SF/MO
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Southline - Building 1

30 Tanforan Avenue, Lindenville, South San Francisco, CA
Property

Office

375,000 SF
Availability

1 Space

325,000 SF
Year Built

2024
For Lease Contact for pricing
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OFFICE SPACE FOR LEASE

510 Myrtle Ave, Orange Park, South San Francisco, CA
Property

Office
Availability

1 Space

759 SF
Year Built

1984
For Lease

$2.15/SF/MO
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Victory Business Center

441 Victory Avenue, Lindenville, South San Francisco, CA
Property

Industrial

32,954 SF
Availability

2 Spaces

6,766 SF
Year Built

1990
For Lease

$1.70 - $1.95/SF/MO
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PS BUSINESS PARK

90 S Spruce Ave, Orange Park, South San Francisco, CA
Property

Office
Availability

5 Spaces

7,162 SF
Year Built

1986
For Lease

$1.75 - $1.95/SF/MO
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Produce Avenue Business Park

100 Produce Avenue, Lindenville, South San Francisco, CA
Property

Office

41,448 SF
Availability

2 Spaces

3,917 SF
Year Built

1986
For Lease

$0.80 - $1.50/SF/MO
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Gateway Crossing - 201 & 225 Gateway Blvd

225 Gateway Blvd, Gateway, South San Francisco, CA
Property

Office

106,076 SF
Availability

1 Space

15,559 SF
Year Built

1998
For Lease Contact for pricing
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Edgewater Science Park

260 Littlefield Avenue, The East Side, South San Francisco, CA
Property

Office

169,359 SF
Availability

1 Space

6,139 SF
Year Built

1988
For Lease Contact for pricing
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Britannia Pointe Grand

250 East Grand Avenue, The East Side, South San Francisco, CA
Property

Office

630,500 SF
Availability

6 Spaces

146,211 SF
Year Built

1989
For Lease Contact for pricing
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The Nexus on Grand

233 East Grand Avenue, The East Side, South San Francisco, CA
Property

Office

148,500 SF
Availability

2 Spaces

53,682 SF
Year Built

2023
For Lease Contact for pricing
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Gateway Commons

611 Gateway Blvd, Gateway, S San Francisco, CA
Property

Office

260,337 SF
Availability

1 Space

24,512 SF
Year Built

2002
For Lease

$47.40/SF/YR
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Gateway Commons - 611 Gateway

611 Gateway Blvd, Gateway, South San Francisco, CA
Property

Office

260,337 SF
Availability

2 Spaces

26,383 SF
Year Built

2002
For Lease Contact for pricing
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Gateway Commons - 601 Gateway

601 Gateway Blvd, Gateway, South San Francisco, CA
Property

Office

215,832 SF
Availability

9 Spaces

72,632 SF
Year Built

1984
For Lease

$4.25/SF/MO
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PS BUSINESS PARK

156 S Spruce Ave, Paradise Valley, South San Francisco, CA
Property

Office
Availability

3 Spaces

1,830 SF
For Lease

$1.95/SF/MO
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Frequently Asked Questions

Asking prices vary based on the property location, rating, amenities such as proximity to restaurants, cafes, and entertainment venues, as well as convenience of access to public transport, airports, and thoroughfares.

Among listings of office space currently available for lease in San Bruno, the maximum rental rate is $38 per square foot.

Most experts recommend an average of between 75 and 150 square feet of office space per person. However, it is important to keep in mind that how much office space you ultimately need depends on your activity and how you need to use the space, as much as it does on how many people it should accommodate. If you already know what size office would best suit your needs, use the available space size filter at the top of the search page to focus your search on the best fit for you.

You’ll find a home for almost any size of business in San Bruno, as the local office market offers a wide range of options. Office spaces currently on the market go up to as much as 2,398 square feet in size for an individual listing.

You can find 2 office listing(s) for lease in San Bruno, which add up to a total of 4,407 square feet. Availability on the market includes a variety of office use types, such as Medical Office.

The most common office use type currently available for lease in San Bruno is Medical Office, which is offered in 2 or 100.00% of listings.

Sublease opportunities on the market include Medical Office.

The best choice of neighborhood for your office space will greatly depend on the elements that are most relevant to your business and your employees. However, a good criterion to start with is to look at the areas of the city that have the highest concentration of office properties, as these areas are generally well connected to transit options and have a good degree of amenity availability.

Each individual’s commuting experience will of course be different depending on a number of factors. Check the location description details for the office listings that catch your eye, to get an overview of walkability, access to public transport, the quality of infrastructure dedicated to biking commuters, as well as the proximity to parking facilities, fuel stations, and other essential amenities.

The San Bruno office market incorporates a mix of properties of various ages, ratings, construction grades, and other quality indicators. Class B office space accounts for 100% of spaces listed on the leasing market.

There are, of course, a lot of things to factor in when you are looking for office space. Aspects including the accessibility of the location, the quality of the facility, the size of the space, the convenience of nearby amenities, the type and duration of the lease, and of course the cost are all part of the search and decision process. For a quick checklist of what you should take into account when researching the market, consider these seven tips for choosing the best office location for your business. Alternatively, for a comprehensive take on everything to consider when looking for office space, see our in-depth guide to finding office space for small or growing companies. The guide also includes insights from seasoned professionals and can serve as a helpful resource for growing companies, no matter their current size.

Are you looking to lease office space in the vicinity of your current location or in a particular neighborhood of San Bruno? Using the interactive map, you can easily navigate to your preferred location and customize your search area around a specific point of interest. Select “Radius” from the Search Mode options menu, click on the map to set your search reference point, and expand the radius to select your desired search area. Browse available listings to find the best office space that meets your location, as well as other business needs.

San Bruno, CA Office Inventory Breakdown

There are a number of factors that make a city attractive for businesses to relocate or expand, as well as for investors to enhance their portfolios through local acquisitions. Among the most important factors to consider are the size and quality of the local office market, which is an essential component of the local economy.

Total Office Space in San Bruno: 5,913,496 Sq. Ft.

In 2024 the San Bruno office market encompassed 5,913,496 square feet of space.
Class A office space makes up a 32.51% share of San Bruno office inventory, while Class B office assets represent roughly 4.02% of the market total.

San Bruno Office Market Breakdown by Building Size
Building Size Range	Total Square Feet	Share of Total Office
50k to 100k Sq. Ft.	319,732 Sq. Ft.	5.41%
100k to 500k Sq. Ft.	1,876,473 Sq. Ft.	31.73%
> 1M Sq. Ft.	3,673,115 Sq. Ft.	62.11%

San Bruno Office Market Breakdown by Building Quality Rating
Class	Total Square Feet	Share of Total Office
Class A	1,922,449 Sq. Ft.	32.51%
Class B	237,762 Sq. Ft.	4.02%
Class C	80,170 Sq. Ft.	1.36%

Data was provided by CommercialEdge, refers to properties larger than 50,000 square feet.

39 Office Spaces for Rent in San Bruno, CA

San Bruno Medical Office Building

365 South Spruce Avenue

Southline - Building 1

OFFICE SPACE FOR LEASE

Victory Business Center

PS BUSINESS PARK

Produce Avenue Business Park

Gateway Crossing - 201 & 225 Gateway Blvd

Edgewater Science Park

Britannia Pointe Grand

The Nexus on Grand

Gateway Commons

Gateway Commons - 611 Gateway

Gateway Commons - 601 Gateway

PS BUSINESS PARK

Frequently Asked Questions

San Bruno, CA Office Inventory Breakdown

Total Office Space in San Bruno: 5,913,496 Sq. Ft.

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39 Office Spaces for Rent in San Bruno, CA

Frequently Asked Questions

How much does office space cost in San Bruno, CA?

How much office space do I need?

What types of office space can I lease in San Bruno, CA?

Can I find sublease office space in San Bruno, CA?

Where is the best location for office space in San Bruno, CA?

How long is the average commute to work in San Bruno, CA?

Where can I find the highest quality office space in San Bruno, CA?

How do I find the best office space in San Bruno, CA?

How can I find office space for rent near me?

San Bruno, CA Office Inventory Breakdown

Total Office Space in San Bruno: 5,913,496 Sq. Ft.

Other Popular Searches

Popular Coworking Searches

About us