1109 22nd Street South

1109 22nd Street South, Birmingham, AL 35205

Property Information

  • For Lease $18.00/SF/YR
  • Property Type Office - General Office
  • Property Size 5,010 SF
  • Building Class B
  • Year Built 1911
  • Year Renovated 2016
  • Date Updated Oct 21, 2026

Description

Located in the 5 Points South area of Birmingham, just blocks from UAB and UAB St. Vincent’s, with immediate access to major employment, medical, legal, technology, and professional office uses.Located in one of Birmingham’s most sought-after professional corridors, 1109 22nd Street South provides immediate access to the city’s largest employment center and is surrounded by multi-million-dollar developments and redevelopment projects. Positioned just blocks from UAB and UAB St. Vincent’s, the property is surrounded by medical, legal, technology, and professional office users while remaining minutes from Downtown Birmingham, Homewood, Mountain Brook, and Vestavia Hills.Located in one of Birmingham’s most sought-after professional corridors, 1109 22nd Street South provides immediate access to the city’s largest employment center and is surrounded by multi-million-dollar developments and redevelopment projects. Positioned just blocks from UAB and UAB St. Vincent’s, the property is surrounded by medical, legal, technology, and professional office users while remaining minutes from Downtown Birmingham, Homewood, Mountain Brook, and Vestavia Hills.

Highlights

  • Additional Income Opportunity: A separate one-bedroom Airbnb apartment with private rear access provides supplemental income potential or executive housing for visiting employees and clients.
  • Exceptional Interior Character: Beautiful hardwood floors, oversized windows, original architectural detailing, generous ceiling heights, and abundant natural light
  • Flexible Occupancy: Available for sale or lease with suites ranging from 1,750 SF to 5,010 SF, making the property ideal for owner-users or growing businesses.
  • Historic Architecture Meets Modern Functionality: Originally constructed in 1911, this character-rich office building underwent an extensive renovation in 2016, preserving its historic charm while delivering modern office functionality.
  • Versatile Layout: Great mix 6-7 private offices and open workspace

1 Space Available

1109 22nd Street

Space Type

Office

Lease Rate

$18.00/SF/YR

Total Space

5,010 SF

Divisible Space

1,750 - 5,010 SF

Available Date

Immediate

Lease Type

Full Service

Renewal Option

Yes

Sublease

No

Available suites range from 1,750 SF to 5,010 SF.

Contacts

Location

Located at 1109 22nd Street South, Birmingham, AL 35205, this property is part of the Five Points South neighborhood and Birmingham market.

Contact Listing Broker
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