Historic Downtown Harrison Avenue Corner Drug Store Retail Location - Up to 12,700 SF For Lease

Positioned at the corner of Harrison Avenue and 5th Street, this building benefits from excellent foot traffic, visibility, and proximity to key downtown attractions. Located just four blocks from the marina and within walking distance of downtown's revitalized shops and businesses, 485 Harrison Avenue anchors Historic Downtown Panama City's main street.485 Harrison Avenue offers a rare opportunity to lease a prominent historic retail building in the heart of downtown Panama City. This two-story, ±12,700 SF building is situated on a high-visibility corner at Harrison Avenue and 5th Street, steps from government offices, banks, restaurants, and waterfront amenities. With vintage charm, expansive storefront windows, and flexible configurations, this former drugstore has long served as a landmark in the community. Space Options Being Considered: 1. Full Building – ±12,700 SF (Two Floors) Ideal for a flagship retail or mixed-use concept Includes ±8,608 SF on the ground floor and ±4,098 SF upstairs Prominent corner signage and dual street frontage Access to both floors via internal staircase 2. Ground Floor Only – ±8,608 SF High ceilings, open retail floorplate, and natural light Move-in-ready zones with private offices, kitchen, and restrooms Excellent for retail showroom, food/beverage, or gallery use 3. Multi-Tenant Ground Floor Concept – ±2,500 to ±6,000 SF Suites Options Proposed three-suite / multi-tenant layout with units sizes ranging of approximately 2,500, 5,000 to 6,000 +/- SF combinations Each space has direct exterior access and storefront exposure Ideal for boutique shops, local service providers, or small food/beverage operators *Pricing & timeline to be determined if multi-tenant options are pursued