Historic Downtown Harrison Avenue Corner Drug Store Retail Location - Up to 12,700 SF For Lease

485 Harrison Avenue, Panama City, FL 32401

Property Information

  • For Lease Contact for pricing
  • Property Type Retail - Street Retail
  • Property Size 12,700 SF
  • Lot Size 0.19 Acre
  • Property Tenancy Single Tenant
  • Year Built 1930
  • Year Renovated 2019
  • Date Updated May 17, 2026

Description

Positioned at the corner of Harrison Avenue and 5th Street, this building benefits from excellent foot traffic, visibility, and proximity to key downtown attractions. Located just four blocks from the marina and within walking distance of downtown's revitalized shops and businesses, 485 Harrison Avenue anchors Historic Downtown Panama City's main street.485 Harrison Avenue offers a rare opportunity to lease a prominent historic retail building in the heart of downtown Panama City. This two-story, ±12,700 SF building is situated on a high-visibility corner at Harrison Avenue and 5th Street, steps from government offices, banks, restaurants, and waterfront amenities. With vintage charm, expansive storefront windows, and flexible configurations, this former drugstore has long served as a landmark in the community. Space Options Being Considered: 1. Full Building – ±12,700 SF (Two Floors) Ideal for a flagship retail or mixed-use concept Includes ±8,608 SF on the ground floor and ±4,098 SF upstairs Prominent corner signage and dual street frontage Access to both floors via internal staircase 2. Ground Floor Only – ±8,608 SF High ceilings, open retail floorplate, and natural light Move-in-ready zones with private offices, kitchen, and restrooms Excellent for retail showroom, food/beverage, or gallery use 3. Multi-Tenant Ground Floor Concept – ±2,500 to ±6,000 SF Suites Options Proposed three-suite / multi-tenant layout with units sizes ranging of approximately 2,500, 5,000 to 6,000 +/- SF combinations Each space has direct exterior access and storefront exposure Ideal for boutique shops, local service providers, or small food/beverage operators *Pricing & timeline to be determined if multi-tenant options are pursued Operating expenses: $2.91 sq ft

Highlights

  • Flexible Floorplans: Options for full-building, single-floor, or multi-tenant use
  • Historic Character: Formerly the downtown corner drugstore with postcard-worthy prominence
  • Iconic Downtown Corner: Prime visibility at Harrison Avenue & 5th Street
  • Large Storefront Windows: Expansive glass line ideal for display and branding
  • Walkable Location: Surrounded by restaurants, government offices, and waterfront

2 Spaces Available

Space Type

Retail

Lease Rate

$15.00/SF/YR

Total Space

12,700 SF

Divisible Space

12,700 - 12,700 SF

Available Date

Immediate

Lease Type

NNN

Renewal Option

Yes

Sublease

No

TBD

Space Type

Street Retail

Lease Rate

Contact for pricing

Total Space

2,500 SF

Floor

1st

Divisible Space

2,500 - 8,600 SF

Available Date

Immediate

Lease Type

NNN

Renewal Option

Yes

Sublease

No

Contacts

Kevin Wattenbarger

Five Bridges Real Estate Services

Location

Located at 485 Harrison Avenue, Panama City, FL 32401, this property is part of the Downtown Panama City neighborhood and Pensacola market.

Contact Listing Broker
Kevin Wattenbarger

Five Bridges Real Estate Services

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