52 & Main

12021 Main St, San Antonio, FL 33576

Property Information

  • For Sale Subject To Offer
  • Property Type VacantLand
  • Property Size 1,284 SF
  • Units 1
  • Lot Size 1.56 Acre
  • Year Built 1940
  • Date Updated Sep 24, 2026

Description

The property is on Main Street in the historic town of San Antonio in east Pasco County, one of the oldest incorporated communities in the county and known for its small town charm and walkable downtown core. Founded in 1882, the town still centers on its Main Street and hosts the well known San Antonio Rattlesnake Festival that draws visitors from across the region each year. It sits just off State Road 52 with direct access to Interstate 75 at Exit 285, tying the town to the greater Tampa Bay region and to the U.S. 301 corridor through neighboring Dade City. Saint Leo University and the Lake Jovita golf community are next door, and East Pasco has become one of the fastest growing parts of one of the fastest growing counties in Florida with new housing pushing east along the SR 52 corridor toward San Antonio. The result is a rare mix of established historic character and real growth momentum in the path of the region's expansion.The property is 1.56 acres in downtown San Antonio zoned C2, the county's general commercial district. It carries roughly 275 feet of frontage on State Road 52 with additional access off both Main Street and Hill Avenue. The C2 zoning supports a broad range of retail office and commercial uses. Given its size frontage and setting in the heart of town the site also lends itself to a community gathering concept such as a weekly farmers and artisan market that could anchor downtown San Antonio and draw steady foot traffic. The highway frontage, dual access and flexible zoning make it a strong infill commercial site with room for a creative vision.

Contacts

Location

Located at 12021 Main St, San Antonio, FL 33576, this property is part of the San Antonio neighborhood and Tampa St Petersburg Clearwater market.

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