What type of office space is available to lease at Two Discovery Square?

The property includes 5 Office spaces located on 5 floors. Availabilities total 63,556 square feet of office space.

Is Two Discovery Square suitable for a small business?

Yes, availabilities here may be suitable for small businesses with 1 office space under 5,000 square feet available.

Does Two Discovery Square have enough space for a large business?

Yes, availabilities here could accommodate larger businesses with 3 office spaces larger than 10,000 square feet available for lease. The largest office size is 22,467 SF, located on floor 5. For a better understanding of how this space could work for you, reach out to schedule a tour.

Does Two Discovery Square have parking?

Parking information for the property isn't currently listed. However, other nearby parking options include Mayo Block 6 Parking Ramp, located 0.07 miles away, and 3rd Street Parking Ramp, which is 0.14 miles away.

Two Discovery Square

415 2nd Ave SW, Rochester, MN 55902

Property Information

For Lease Contact for pricing
Property Type Office
Property Size 125,000 SF
Date Updated Jan 27, 2026

Description

Two Discovery Square offers life science innovators a state-of-the-art 125,000 square foot facility designed for groundbreaking research. As part of Mayo Clinic’s ecosystem, tenants gain access to specialized research cores, cuttingedge technology, and expert guidance. The facility seamlessly integrates with Mayo’s unique data pipelines and the Discovery and Translation Alliance spectrum, accelerating the path from idea to real-world medical solutions

5 Spaces Available

1st Floor

Space Type

Office

Lease Rate

Contact for pricing

Total Space

1,163 SF

Floor

Divisible Space

1,163 - 1,163 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

2nd Floor

Space Type

Office

Lease Rate

Contact for pricing

Total Space

13,032 SF

Floor

Divisible Space

13,032 - 13,032 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

3rd Floor

Space Type

Office

Lease Rate

Contact for pricing

Total Space

21,544 SF

Floor

Divisible Space

21,544 - 21,544 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

4th Floor

Space Type

Office

Lease Rate

Contact for pricing

Total Space

5,350 SF

Floor

Divisible Space

5,350 - 5,350 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

5th Floor

Space Type

Office

Lease Rate

Contact for pricing

Total Space

22,467 SF

Floor

Divisible Space

22,467 - 22,467 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

Contacts

Jessica Mogilka

Jones Lang LaSalle

Will McArdle

Jones Lang LaSalle

92/100 Walker's Paradise
84/100 Very Bikeable

Contact Two Discovery Square

First name

Last name

Phone number

Capacity range

Company

Monthly budget

Message

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

CommercialCafe is a marketing lead generator. By continuing, you agree to the CommercialCafe Terms Of Service and Privacy Policy.

Nearby Listings

202 4th St SW

202 4th St SW, Rochester, MN

Contact for pricing

Property

Office
81,000 SF

Availability

2 Spaces
4,743 SF

China Hall Professional Loft

218 1st Ave SW, Rochester, MN

$800.00/MO

Property

Office
1,792 SF

Availability

1 Space
140 SF

The Historic Broadway Loft Office

318 Broadway Ave S, Rochester, MN

$17.00/SF/YR

Property

Office
1,795 SF

Availability

1 Space
1,795 SF

206 South Broadway Professional Building

206 S Broadway , Rochester, MN

$18.50/SF/YR

Property

Office
34,330 SF

Availability

9 Spaces
32,654 SF

Iconic Downtown Lease Space in the Historic Kahler Building

7 1st Ave SW, Rochester, MN

$19.00/SF/YR

Property

Office

Availability

16 Spaces
34,403 SF

Frequently Asked Questions

The property includes 5 Office spaces located on 5 floors. Availabilities total 63,556 square feet of office space.
Yes, availabilities here may be suitable for small businesses with 1 office space under 5,000 square feet available.
Yes, availabilities here could accommodate larger businesses with 3 office spaces larger than 10,000 square feet available for lease. The largest office size is 22,467 SF, located on floor 5. For a better understanding of how this space could work for you, reach out to schedule a tour.
Parking information for the property isn't currently listed. However, other nearby parking options include Mayo Block 6 Parking Ramp, located 0.07 miles away, and 3rd Street Parking Ramp, which is 0.14 miles away.

Two Discovery Square

415 2nd Ave SW, Rochester, MN 55902

Property Information

Description

5 Spaces Available

1st Floor

2nd Floor

3rd Floor

4th Floor

5th Floor

Contacts

Location

Nearby Listings

202 4th St SW

China Hall Professional Loft

The Historic Broadway Loft Office

206 South Broadway Professional Building

Iconic Downtown Lease Space in the Historic Kahler Building

Frequently Asked Questions

Popular Searches