What is the price for renting office space at 4321 Medical Park Dr?

The price for office space here is $23.00/SF/YR.

What type of office space is available to lease at 4321 Medical Park Dr?

In total, there is 18,921 square feet of office space for lease here. Availability at this location includes 3 Office spaces.

Is 4321 Medical Park Dr suitable for a small business?

Yes, availabilities here may be suitable for small businesses with 2 office spaces under 5,000 square feet available. Space sizes here start at 4,257 square feet.

Does 4321 Medical Park Dr have enough space for a large business?

Yes, availabilities here could accommodate larger businesses with 1 office space larger than 10,000 square feet available for lease. The largest office size is 10,056 SF. For a better understanding of how this space could work for you, reach out to schedule a tour.

Does 4321 Medical Park Dr have parking?

Parking information for the property isn't currently listed. However, other nearby parking options include Saint Lukes Episcopal Church, located 2.91 miles away, and Biddle Music Parking Lot, which is 3 miles away.

4321 Medical Park Dr

4321 Medical Park Dr, Durham, NC 27704

Property Information

See Attachment

For Lease $23.00/SF/YR
Property Type Office - General Office
Property Size 79,440 SF
Lot Size 8.17 Acre
Building Class A
Year Built 2001
Date Updated Aug 3, 2026

Description

4321 Medical Park Drive is a Class A office building located in a large medical hub, Independence Park, across from Duke Regional Hospital in North Durham. The thriving park contains various medical and health-related occupants as well as retail and restaurants nearby. Downtown Durham and Duke University are only 4 and 5 miles away respectively.4321 Medical Park Drive is a Class A office building located in a large medical hub, Independence Park, across from Duke Regional Hospital in North Durham. The thriving park contains various medical and health-related occupants as well as retail and restaurants nearby. Downtown Durham and Duke University are only 4 and 5 miles away respectively.

Highlights

79,202 SF two-story medical and office building
Ability to combine suites for up to 29,098 RSF
Built in 2001 - attractive concrete, steel and glass construction
Dock loading in rear of building
Freight elevator and backup generator onsite
Gorgeous atrium with circular staircase
High ceilings and upgraded finishes
Lease rate: $23.00/SF full service
Plentiful parking onsite (4.8 per 1,000 SF)

3 Spaces Available

Suite 2

Space Type

Office

Lease Rate

$23.00/SF/YR

Total Space

4,257 SF

Divisible Space

4,257 - 18,921 SF

Available Date

Immediate

Lease Type

Full Service

Renewal Option

Yes

Sublease

Suite 3

Space Type

Office

Lease Rate

$23.00/SF/YR

Total Space

4,608 SF

Divisible Space

4,608 - 18,921 SF

Available Date

Immediate

Lease Type

Full Service

Renewal Option

Yes

Sublease

Suite 4

Space Type

Office

Lease Rate

$23.00/SF/YR

Total Space

10,056 SF

Divisible Space

10,056 - 18,921 SF

Available Date

Immediate

Lease Type

Full Service

Renewal Option

Yes

Sublease

Contacts

Brian Farmer

Location

Located at 4321 Medical Park Dr, Durham, NC 27704, this property is part of the Summer Meadow neighborhood and Raleigh Durham market.

Map
Street

20/100 Car-Dependent
30/100 Some Transit
30/100 Somewhat Bikeable

Contact Listing Broker

Brian Farmer

First name

Last name

Phone number

Capacity range

Company

Monthly budget

Message

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Frequently Asked Questions

The price for office space here is $23.00/SF/YR.
In total, there is 18,921 square feet of office space for lease here. Availability at this location includes 3 Office spaces.
Yes, availabilities here may be suitable for small businesses with 2 office spaces under 5,000 square feet available. Space sizes here start at 4,257 square feet.
Yes, availabilities here could accommodate larger businesses with 1 office space larger than 10,000 square feet available for lease. The largest office size is 10,056 SF. For a better understanding of how this space could work for you, reach out to schedule a tour.
Parking information for the property isn't currently listed. However, other nearby parking options include Saint Lukes Episcopal Church, located 2.91 miles away, and Biddle Music Parking Lot, which is 3 miles away.

4321 Medical Park Dr

4321 Medical Park Dr, Durham, NC 27704

Property Information

Description

Highlights

3 Spaces Available

Suite 2

Suite 3

Suite 4

Contacts

Location

Located at 4321 Medical Park Dr, Durham, NC 27704, this property is part of the Summer Meadow neighborhood and Raleigh Durham market.

Nearby Listings

4020 North Roxboro Street

Durham Summit

110 E. Carver Street

1101 Hamlin Road

3209 Guess Rd

Frequently Asked Questions

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