Syracuse, NY Commercial Real Estate for Lease and Sale
Explore 171 listing(s) of commercial real estate in Syracuse, NY to find the best space for your business.
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3522 James St, Eastwood, Syracuse, NYSpace Type- Office
For Lease Contact for pricing -
301 South Salina Street, Downtown Syracuse, Syracuse, NYProperty Type- Mixed Use
For Sale- $3,100,000
Built in 1920 / Property size 56,000 SF -
210 Hamilton Street, Far Westside Syracuse, Syracuse, NYProperty Type- Other
For Sale- $2,300,000
Property size 1,625 SF -
3522 James St, Eastwood, Syracuse, NYSpace Type- Office
For Lease Contact for pricing -

What type of listing property are you looking for?
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100 East Washington St Syracuse, Downtown Syracuse, Syracuse, NYSpace Type- Office
For Lease- $16.00/SF/YR
1 space available / 3,034 SF -
500 Plum Street, Lakefront, Syracuse, NYSpace Type- Office
For Lease- $20.00/SF/YR
1 space available / 7,054 SF -
3522 James Street, Eastwood, Syracuse, NYSpace Type- Office
For Lease Contact for pricing -
2005 W Genesee St, Far Westside Syracuse, Syracuse, NYSpace Type- Office
For Lease Contact for pricing -
647 W Genesee St, Westside Syracuse, Syracuse, NYProperty Type- Retail
For Sale- $1,950,000
Built in 1940 / Property size 37,170 SF -
224 Harrison St, Suite 210, Syracuse, NYJF Real Estate - ShareCuse
JF Real EstateSpace Type- Private Offices
For Lease-
From $450/month
Space for 1 to 3 people -
100 North Salina Street, Downtown Syracuse, Syracuse, NYSpace Type- Office
For Lease- $17.00/SF/YR
1 space available / 6,985 SF -
301 South Salina Street, Downtown Syracuse, Syracuse, NY -
1417-31 Valley Drive, North Valley, Syracuse, NYProperty Type- Retail
For Sale- $699,000
Built in 1935 / Property size 11,320 SF -
3522 James St, Eastwood, Syracuse, NYSpace Type- Office
For Lease Contact for pricing -
809A North Salina Street, Washington Square, Syracuse, NYSpace Type- Office
For Lease- $1,325.00/MO
1 space available / 1,020 SF -
333 West Washington Street, Downtown Syracuse, Syracuse, NYSpace Type- Office
For Lease- $22.00/SF/YR
1 space available / 3,041 SF -
3522 James St, Eastwood, Syracuse, NYSpace Type- Office
For Lease Contact for pricing -
205 South Salina Street, Downtown Syracuse, Syracuse, NYSpace Type- Retail
For Lease Contact for pricing -
3522 James st Eastwood/DeWitt, Eastwood, Syracuse, NYSpace Type- Mixed Use
For Lease Contact for pricing -
2 Clinton Square, Downtown Syracuse, Syracuse, NYSpace Type- Office
For Lease Contact for pricing -
900 W Genesee St, Westside Syracuse, Syracuse, NYProperty Type- Multi-Family
For Sale- Subject To Offer
Built in 2010 / Property size 29,015 SF -
701 South Geddes Street, Near Westside Syracuse, Syracuse, NYProperty Type- Retail
For Sale- $1,495,000
Built in 1920 / Property size 38,552 SF -
300 East Washington Street, Downtown Syracuse, Syracuse, NYSpace Type- Restaurant
For Lease- $12.92/SF/YR
1 space available / 2,880 SF -
1401 Erie Blvd East, Near Eastside Syracuse, Syracuse, NY -
123 Larned Street, Southwest Syracuse, Syracuse, NY -
450 South Salina Street, Downtown Syracuse, Syracuse, NYSpace Type- Office
For Lease- $15.00/SF/YR
1 space available / 8,500 SF -
223 Pulaski Street, Lakefront, Syracuse, NYProperty Type- Industrial
For Sale- $1,800,000
Built in 1930 / Property size 11,858 SF -
1004 E Adams St, University Hill, Syracuse, NYProperty Type- Retail
For Sale- Subject To Offer
Property size 13,200 SF -
600 East Genesee Street, Downtown Syracuse, Syracuse, NYSpace Type- Office
For Lease- $15.95/SF/YR
1 space available / 11,936 SF -
400 South Salina Street, Downtown Syracuse, Syracuse, NY -
731 James Street, Near Northeast Syracuse, Syracuse, NYSpace Type- Office
For Lease- $14.00/SF/YR
3 spaces available / 1,230 - 1,650 SF -
222 Teall Avenue, Near Eastside Syracuse, Syracuse, NYSpace Type- Retail
For Lease- $19.00/SF/YR
2 spaces available / 2,153 - 7,896 SF -
2108- 2122 Erie Boulevard East, Salt Springs, Syracuse, NY -
224 Harrison Street, Downtown Syracuse, Syracuse, NYSpace Type
- Office
For Lease- $12.50 - $16.00/SF/YR
5 spaces available / 500 - 7,677 SF -
1312 Butternut Street, Northside Syracuse, Syracuse, NYProperty Type- Multi-Family
For Sale- $3,645,000
Built in 1960 / Property size 41,991 SF -
110 Townsend St S, Downtown Syracuse, Syracuse, NYSpace Type- Industrial
For Lease- $6.50/SF/YR
1 space available / 13,134 SF -
109 South Warren Street, Downtown Syracuse, Syracuse, NY -
100 Madison Street, Downtown Syracuse, Syracuse, NYSpace Type- Office
For Lease- $17.50/SF/YR
1 space available / 14,251 SF -
3522 James St, Eastwood, Syracuse, NYSpace Type- Healthcare
For Lease Contact for pricing -
530 State Fair Blvd, Lakefront, Syracuse, NYSpace Type- Industrial
For Lease- $6.00 - $6.50/SF/YR
1 space available / 15,000 SF -
650 James Street, Near Northeast Syracuse, Syracuse, NYSpace Type- Office
For Lease- $14.00/SF/YR
2 spaces available / 5,000 - 9,000 SF -
250 Harrison Street, Downtown Syracuse, Syracuse, NYSpace Type- Retail
For Lease- $16.00/SF/YR
1 space available / 2,302 SF -
980 James Street, Lincoln Hill, Syracuse, NYSpace Type- Office
For Lease- $18.00/SF/YR
1 space available / 11,000 SF -
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2140 Erie Blvd E, Salt Springs, Syracuse, NY -
235 Harrison Street, Syracuse, NYInspyre Innovation Hub - 235 Harrison Street
Inspyre Innovation Hub -
500 Brookford Road, Meadowbrook, Syracuse, NYProperty Type- Office
For Sale- $1,495,000
Property size 25,871 SF -
221 Herald Place, Downtown Syracuse, Syracuse, NY -
700 Erie Blvd East, Near Eastside Syracuse, Syracuse, NY -
210 West Division Street, Lakefront, Syracuse, NY -
171 Marshall Street, University Hill, Syracuse, NYProperty Type- Retail
For Sale- $9,000,000
Built in 1940 / Property size 6,200 SF -
112 Dewitt St, Sedgwick, Syracuse, NYSpace Type- Office
For Lease- $1,400.00/MO
1 space available / 951 SF -
221 South Warren Street, Downtown Syracuse, Syracuse, NY