Map of Property

Two Suites Available for Lease in Office/Medical Building | Columbia

4100 N Main St, Columbia, SC 29203

  • For Lease Contact for pricing
  • Property Type Office - General Office
  • Year Renovated 2019
  • Date Updated May 9, 2025

Located at 4100 North Main Street, these two contiguous suites are available in a two-story freestanding office building. The building was recently renovated in 2019 and sits on a large ±1.3-acre lot, providing ample parking for tenants and clients. The property is situated in the North Main (NOMA) district of Downtown Columbia. The location offers convenient access to Downtown Columbia, Prisma Health Richland Hospital, Interstate 126 and Highway 277.

Available suites for lease:

Suite 200 | ±1,226 SF
Suite 201 | ±2,516 SF
Can be combined for a total contiguous area of ±3,742 SF

For more information, please download the flyer and contact the listing brokers, Tommy Johnson or Mary Winter Teaster.

Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

Attachments

Highlights

  • ±2 miles to Bull Street District
  • ±2 miles to Downtown Columbia and Prisma Health Richland Hospital
  • Generous on-site parking
  • Predominantly configured for clinical and medical uses, but can also support traditional office use
  • Property managed by Colliers

Spaces Available

Contacts

broker
Thomas Johnson

Colliers

broker
Mary Teaster

Colliers

Location

Getting Around

  • Walk Score ®

    63/100 Somewhat Walkable

  • Transit Score ®

    32/100 Some Transit

  • Bike Score ®

    37/100 Somewhat Bikeable
Powered by Walk Score ®
  • City Columbia, SC
  • Neighborhood Seminary Ridge
  • Zip Code 29203
  • Market Columbia

Points of Interest

  • Columbia

    3.15 miles

  • Sunoco

    0.30 miles

  • Speedway

    0.51 miles

  • Shell

    0.84 miles

  • Marathon

    1.90 miles

  • Exxon

    1.90 miles

  • BP

    1.92 miles

  • Flying J

    1.95 miles

  • Columbia, SC Supercharger

    6.86 miles

  • Columbia, SC - Harbison Boulevard Supercharger

    7.04 miles

  • Circle K

    8.96 miles

  • Prisma Health Baptist Hospital Parking

    2.24 miles

  • P. Cannon Garage

    2.27 miles

  • Taylor Street Garage

    2.30 miles

  • Parking of CSH

    2.43 miles

  • AD7 Lot

    2.47 miles

  • Lady Street Parking Garage

    2.65 miles

  • AD12

    2.95 miles

  • B6 Lot

    3.00 miles

  • 901 Park St Garage

    3.01 miles

  • Park View Inn

    0.79 miles

  • Super 8 by Wyndham Columbia

    1.86 miles

  • Glass Manor

    1.94 miles

  • Staybridge Suites

    2.30 miles

  • Hotel Trundle

    2.31 miles

  • Columbia Marriott

    2.41 miles

  • Coronet

    2.42 miles

  • Holiday Inn Columbia - Downtown

    2.46 miles

  • Sheraton Columbia Downtown Hotel

    2.48 miles

  • Suburban Extended Stay Hotel

    2.54 miles

  • Church's Chicken

    0.06 miles

  • Zesto

    0.09 miles

  • Papa John's

    0.32 miles

  • Silver Moon

    0.49 miles

  • China Wing Basket

    0.54 miles

  • King's Chef Chinese

    0.66 miles

  • Burger King

    0.67 miles

  • Sonic

    0.73 miles

  • Subway

    0.79 miles

  • Johnson's

    0.87 miles

  • Hyatt Park School

    0.14 miles

  • Eau Claire High School

    0.60 miles

  • Columbia College

    0.70 miles

  • Heyward Gibbes Middle School

    0.86 miles

  • Withers School

    0.91 miles

  • Ridgewood School

    0.97 miles

  • Alcorn Middle School

    1.16 miles

  • Burton School

    1.17 miles

  • Arden Elementary School

    1.22 miles

  • Nance School

    1.30 miles

  • Palmetto Kids Childrens Center

    1.38 miles

  • R. Herman Wright Child Care Center

    3.34 miles

  • Epworth Children's Home of the Methodist Church

    3.50 miles

  • Incarnation Child Development Center

    3.73 miles

  • Montessori School of Columbia

    4.23 miles

  • Dents Adult Daycare Service

    5.12 miles

  • The Sunshine House

    5.43 miles

  • Covenant Christian Academy & Daycare

    7.25 miles

  • Sunshine House

    7.26 miles

  • La Petite Academy

    7.61 miles

Frequently Asked Questions

What type of office space is available to lease at Two Suites Available for Lease in Office/Medical Building | Columbia?

In total, there is 3,742 square feet of office space for lease here. Availability at this location includes 1 Office space.

Is Two Suites Available for Lease in Office/Medical Building | Columbia suitable for a small business?

Yes, availabilities here may be suitable for small businesses with 1 office space under 5,000 square feet available.

Does Two Suites Available for Lease in Office/Medical Building | Columbia have parking?
Parking information for the property isn't currently listed. However, other nearby parking options include Prisma Health Baptist Hospital Parking, located 2.24 miles away, and P. Cannon Garage, which is 2.27 miles away.
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