Lee County, FL Commercial Real Estate for Lease and Sale
Explore 770 listing(s) of commercial real estate in Lee County, FL to find the best space for your business.
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13630 Goldenwood Drive, Southwest Florida Airport, Fort Myers, FL -
19651 South Tamiami Trail, The Vines, Fort Myers, FLProperty Type- VacantLand
For Sale- $1,700,000
Property size 4.5 Acre -
7130 College Pkwy, Villas, Fort Myers, FLSpace Type- Office
For Lease- $22.50/SF/YR
1 space available / 2,340 SF -
3614 5th St W, Lehigh Acres, FL -

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4140/4174 Stringfellow Rd, St. James City, Saint James City, FLProperty Type- Other
For Sale- $469,000
Property size 4.58 Acre -
8095 Toledo Dr, San Carlos Park, Fort Myers, FLProperty Type- VacantLand
For Sale- $1,900,000
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413 NE Van Loon Ln Ste 103, Hancock, Cape Coral, FLSpace Type- Office
For Lease- $15.50/SF/YR
1 space available / 1,215 SF -
10251 Arcos Ave, Plaza del Sol, Estero, FL -
5151 Luckett Rd, Buckingham, Fort Myers, FLProperty Type- VacantLand
For Sale- $8,500,000
Property size 9.23 Acre -
11940 Fairway Lakes Dr, Gateway, Fort Myers, FLProperty Type- Retail
For Sale- $3,170,000
Built in 1992 / Property size 10,485 SF -
N. Cleveland Avenue, Palmona Park, North Fort Myers, FL -
5441 Lee St, Lehigh Acres, FLSpace Type- Industrial
For Lease- $2,000.00 - $3,700.00/MO
2 spaces available / 1,155 - 2,310 SF -
The Oasis 2260 Dr. Martin Luther King Jr. Blvd., Dunbar, Fort Myers, FLProperty Type- Retail
For Sale- $1,750,000
Built in 1980 / Property size 3,960 SF -
4306 Skyline Blvd, Pelican, Cape Coral, FLProperty Type- VacantLand
For Sale- $17.00 - $19.00 PSF
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1830 Del Prado Blvd S, Hancock, Cape Coral, FL -
1288 North Tamiami Trail, North Fort Myers, FLProperty Type- Office
For Sale- $2,630,100
Built in 1959 / Property size 15,940 SF -
12800-12871 University Drive Fort Myers, Villas, Fort Myers, FL -
PINE ISLAND RD & DEL PRADO BLVD, Diplomat, Cape Coral, FLSpace Type- Retail
For Lease- $44.00/SF/YR
1 space available / 2,200 SF -
10231 Metro Pkwy, Winkler, Fort Myers, FLSpace Type- Industrial
For Lease- $15.00/SF/YR
1 space available / 2,529 SF -
1027 SW Pine Island Rd, Mariner, Cape Coral, FLProperty Type- VacantLand
For Sale- $3,500,000
Property size 4.83 Acre -
21750 Via Coconut Point, Estero Town Center, Estero, FL -
20500 N Tamiami Trl, North Fort Myers, FLProperty Type- VacantLand
For Sale- Subject To Offer
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2140 Flint Drive, Eastwood Village, Fort Myers, FLProperty Type- VacantLand
For Sale- $1,376,000
Property size 1.72 Acre -
15740 New Hampshire CT, Estero Bay Park, Fort Myers, FLSpace Type- Office
For Lease- $19.75/SF/YR
1 space available / 2,400 SF -
4383 Colonial Blvd, Omni - Heritage Palms, Fort Myers, FLSpace Type- Retail
For Lease- $19.00 - $25.00/SF/YR
3 spaces available / 1,350 - 3,000 SF -
13811 Metropolis Avenue, Villas, Fort Myers, FLSpace Type- Office
For Lease- $29.50/SF/YR
1 space available / 9,581 SF -
12730 New Brittany Blvd, Villas, Fort Myers, FL -
15501 Old McGregor Blvd, Iona, Fort Myers, FL -
Judd Creek Boulevard, Diplomat, North Fort Myers, FLProperty Type- VacantLand
For Sale- $900,000
Property size 0.84 Acre -
4606 South Cleveland Avenue, Palm Lee, Fort Myers, FLSpace Type- Retail
For Lease- $10.00/SF/YR
1 space available / 45,089 SF -
4409 SE 16th Place, Caloosahatchee, Cape Coral, FLSpace Type- Office
For Lease- $9.00 - $10.50/SF/YR
2 spaces available / 1,381 - 2,765 SF -
16120-16190 Lee Rd, Gateway, Fort Myers, FLSpace Type- Industrial
For Lease- $18.25 - $19.75/SF/YR
10 spaces available / 2,240 - 8,960 SF -
3621 Cleveland Ave, Winkler, Fort Myers, FL -
4011 Colonial Blvd, Omni - Heritage Palms, Fort Myers, FL -
26800 South Tamiami Trail, Bonita Springs, FLSpace Type- Office
For Lease- $24.00/SF/YR
1 space available / 1,484 SF -
23190 Fashion Dr, Coconut Point, Estero, FLSpace Type- Office
For Lease- $23.00/SF/YR
1 space available / 1,593 SF -
4745–4747 13th SW, Lehigh Acres, FL -
7050 Pennsylvania St, Fiddlesticks, Fort Myers, FLSpace Type- Industrial
For Lease- $16,500.00/MO
1 space available / 5,100 SF -
1528-1530 Periwinkle Way, Sanibel, FLSpace Type- Office
For Lease- $30.00/SF/YR
1 space available / 1,125 SF -
1633 NW 32nd Pl, Burnt Store, Cape Coral, FLProperty Type- VacantLand
For Sale- $94,500
Property size 0.45 Acre -
19050 Corkscrew Road, Old Corkscrew, Estero, FL -
809 Southeast 10th Street, Hancock, Cape Coral, FLProperty Type- VacantLand
For Sale- $525,000
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2996 Hanson St, Winkler, Fort Myers, FLProperty Type- Industrial
For Sale- $22,000,000
Built in 2001 / Property size 130,143 SF -
4707 Pine Island Rd NW, Matlacha, FLProperty Type- Retail
For Sale- $893,000
Built in 1936 / Property size 1,838 SF -
11850-11880 Cheeca CT, Miromar Lakes, Fort Myers, FLSpace Type- Retail, Office
For Lease- $17.00 - $34.00/SF/YR
22 spaces available / 1,675 - 5,616 SF -
2350 Champion Ring Rd, Forum, Fort Myers, FL -
7051 Cypress Terrace, Villas, Fort Myers, FLSpace Type- Retail
For Lease- $23.50/SF/YR
2 spaces available / 2,500 - 3,458 SF -
1408 Bayview Court, Edgewood - Morningside, Fort Myers, FLSpace Type- Retail
For Lease- $2,500.00/MO
1 space available / 748 SF -
13500 Riverside Center Ct, Olde Hickory, Fort Myers, FL -
SWC Daniels Pkwy & SR 82, Southwest Florida Airport, Fort Myers, FL -
2500 Diplomat Pkwy E, Diplomat, Cape Coral, FL -
2868-2870 Joel Boulevard, Alva, FLProperty Type- VacantLand
For Sale- Call For Pricing
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1626 Medical Ln, Palm Lee, Fort Myers, FLSpace Type- Office
For Lease- $15.00 - $20.00/SF/YR
1 space available / 27,264 SF