Lee County, FL Commercial Real Estate for Lease and Sale
Explore 781 listing(s) of commercial real estate in Lee County, FL to find the best space for your business.
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1027 SW Pine Island Rd, Mariner, Cape Coral, FLProperty Type- VacantLand
For Sale- $1,800,000
Property size 2.11 Acre -
16103 Lee Rd, Fiddlesticks, Fort Myers, FLSpace Type- Industrial
For Lease- $18.00/SF/YR
1 space available / 2,000 SF -
28811 S. Tamiami Trail, Bonita Springs, FL -
7401 Gladiolus Dr, Estero Bay Park, Fort Myers, FLProperty Type- VacantLand
For Sale- $695,000
Property size 4.21 Acre -

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12210 & 12220 ITEC Haul Dr, Southwest Florida Airport, Fort Myers, FLSpace Type- Industrial
For Lease- $18.00 - $19.00/SF/YR
2 spaces available / 1,500 SF -
5719 Zip Dr, Buckingham, Fort Myers, FLSpace Type- Industrial
For Lease- $13.00/SF/YR
1 space available / 5,100 SF -
15675 McGregor Blvd, Iona, Fort Myers, FL -
1507 Del Prado Blvd S, Hancock, Cape Coral, FL -
311 Del Prado Blvd S, Hancock, Cape Coral, FL -
TBD Lee Blvd., Olympia - Sherwood, Lehigh Acres, FLProperty Type- VacantLand
For Sale- $1,500,000
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8512 Fordham Street, Villas, Fort Myers, FLProperty Type- VacantLand
For Sale- $298,778.04
Property size 7.6 Acre -
1450 East Pointe Dr, Lehigh Acres, FLProperty Type- Other
For Sale- $2,995,000
Property size 3.45 Acre -
3756 Ironbridge Blvd, Winkler, Fort Myers, FLSpace Type- Industrial
For Lease- $14.00/SF/YR
1 space available / 4,623 SF -
4000 Warehouse Road, Winkler, Fort Myers, FLSpace Type- Industrial
For Lease- $10.50/SF/YR
1 space available / 10,600 SF -
16140 Lee Rd, Fort Myers, FL 33912, Fiddlesticks, Fort Myers, FLSpace Type- Industrial
For Lease- $14.00/SF/YR
2 spaces available / 11,200 - 20,160 SF -
2481 Del Prado Boulevard North, Diplomat, Cape Coral, FL -
9200 Estero Park Commons Blvd, Estero Town Center, Estero, FLSpace Type- Office
For Lease- $21.00/SF/YR
1 space available / 1,890 SF -
24830 S. Tamiami Trail, Bonita Springs, FL -
1429 NE 15th Ave, Diplomat, Cape Coral, FL -
25141 Chamber of Commerce Drive, Bonita Springs, FL -
3607 & 3613 Colonial Ct, Forum, FORT MYERS, FL -
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1120 Homestead Rd N, Lehigh Acres, FL -
6700 Bayshore Road, North Fort Myers, FL -
6080 Jonathans Bay Dr, Estero Bay Park, Fort Myers, FL -
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201 SW Pine Island Rd, Mariner, Cape Coral, FL -
10231 Metro Pkwy, Winkler, Fort Myers, FLSpace Type- Industrial
For Lease- $15.00/SF/YR
1 space available / 2,529 SF -
5546 Lee Blvd, Lehigh Acres, FL -
3949 Evans Ave, Condo Unit 307B, Winkler, Fort Myers, FLProperty Type- Office
For Sale- $179,000
Built in 1975 / Property size 1,226 SF -
1591 HAYLEY LN, Palm Lee, Fort Myers, FLSpace Type- Office
For Lease- $12.00/SF/YR
1 space available / 4,250 SF -
5100-5120 Pine Island Rd NW, Pine Island Center, Bokeelia, FLProperty Type- VacantLand
For Sale- $2,200,000
Built in 2021 / Property size 34,250 SF -
5100 Tice Street, Buckingham, Fort Myers, FLProperty Type- Industrial
For Sale- $18,000,000
Built in 1956 / Property size 125,639 SF -
5995 South Pointe Blvd, McGregor, Fort Myers, FLSpace Type- Retail
For Lease- $25.00/SF/YR
1 space available / 3,240 SF -
1243-1306 SW Santa Barbara Blvd, Trafalgar, Cape Coral, FLSpace Type- Retail
For Lease- $18.00/SF/YR
2 spaces available / 1,100 - 1,120 SF -
13379 McGregor Blvd., Cypress Lake, Fort Myers, FLSpace Type- Office
For Lease- $16.00/SF/YR
1 space available / 2,400 SF -
7997 Mercantile St Unit 8, North Fort Myers, FLSpace Type- Office
For Lease- $15.50/SF/YR
1 space available / 2,400 SF -
7050 Pennsylvania St, Fiddlesticks, Fort Myers, FLSpace Type- Industrial
For Lease- $16,500.00/MO
1 space available / 5,100 SF -
17220 San Carlos Blvd, Lakeside, Fort Myers Beach, FLSpace Type- Retail
For Lease- $18.00/SF/YR
1 space available / 9,900 SF -
5216 Summerlin Commons Boulevard, Fort Myers, FLRemote Workspace and Reading Lounge - 5216 Summerlin Commons Boulevard
Remote Workspace and Reading Lounge -
14601 Ben C Pratt 6 Mile Cypress Pkwy, Villas, Fort Myers, FLProperty Type- Special
For Sale- $7,114,515
Built in 1991 / Property size 24,117 SF -
3575 Fowler St, Winkler, Fort Myers, FL -
19050 Corkscrew Road, Old Corkscrew, Estero, FL -
S Tamiami Trail, Estero Bay Park, Fort Myers, FLProperty Type- VacantLand
For Sale- $500,000
Built in 1986 / Property size 1.13 Acre -
627 Cape Coral Parkway West #202, Cape Coral, FLCentrally
CentrallySpace Type- Private Offices
For Lease-
From $850/month
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1349 Old Pondella Road, Hancock, Cape Coral, FLProperty Type- VacantLand
For Sale- $3,150,000
Property size 4.2 Acre -
13401 Palomino Ln, The Renaissance, Fort Myers, FL -
4681 Elevation Way, Poinsettia Park, Fort Myers, FLProperty Type- Industrial
For Sale- $2,946,800
Built in 2021 / Property size 8,471 SF -
5546 LEE BLVD, Lehigh Acres, FL -
7130 College Pkwy, Villas, Fort Myers, FLSpace Type- Office
For Lease- $22.50/SF/YR
1 space available / 2,340 SF -
2350 Champion Ring Rd, Forum, Fort Myers, FL -
16431 SR 31, Fort Myers, FLProperty Type- VacantLand
For Sale- $11,800,000
Property size 100 Acre -
13811 Metropolis Avenue, Villas, Fort Myers, FLSpace Type- Office
For Lease- $29.50/SF/YR
1 space available / 9,581 SF