Onondaga County, NY Commercial Real Estate for Lease and Sale
Explore 385 listing(s) of commercial real estate in Onondaga County, NY to find the best space for your business.
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100 Madison Street, Downtown Syracuse, Syracuse, NYSpace Type- Office
For Lease- $17.50/SF/YR
1 space available / 14,251 SF -
1312 Butternut Street, Northside Syracuse, Syracuse, NYProperty Type- Multi-Family
For Sale- $3,645,000
Built in 1960 / Property size 41,991 SF -
115 Continuum Drive, North Syracuse, Liverpool, NYSpace Type- Office
For Lease- $16.95/SF/YR
3 spaces available / 4,592 - 8,527 SF -
3522 James St, Eastwood, Syracuse, NYSpace Type- Healthcare
For Lease Contact for pricing -

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2 Clinton Square, Downtown Syracuse, Syracuse, NYSpace Type- Office
For Lease Contact for pricing -
809A North Salina Street, Washington Square, Syracuse, NYSpace Type- Office
For Lease- $1,325.00/MO
1 space available / 1,020 SF -
1111 Vine Street, North Syracuse, Liverpool, NYSpace Type- Industrial
For Lease Contact for pricing -
110 Monarch Drive, North Syracuse, Liverpool, NYSpace Type- Land
For Lease- $900.00/SF/YR
1 space available / 6,534 SF -
8132 Oswego Rd, North Syracuse, Liverpool, NYSpace Type- Office
For Lease- $14.00 - $16.00/SF/YR
1 space available / 1,575 SF -
1367 New York 5, Elbridge, NYProperty Type- Multi-Family
For Sale- $497,000
Property size 1 SF -
900 W Genesee St, Westside Syracuse, Syracuse, NYProperty Type- Multi-Family
For Sale- Subject To Offer
Built in 2010 / Property size 29,015 SF -
6864 E Genesee St, East Syracuse, Fayetteville, NYSpace Type- Office
For Lease- $2,975.00/MO
1 space available / 2,500 SF -
2005 W Genesee St, Far Westside Syracuse, Syracuse, NYSpace Type- Office
For Lease Contact for pricing -
1326 New Seneca Tpke, Skaneateles, NYSpace Type- Office
For Lease Contact for pricing -
3522 James st Eastwood/DeWitt, Eastwood, Syracuse, NYSpace Type- Mixed Use
For Lease Contact for pricing -
445 Electronics Pkwy, North Syracuse, Liverpool, NYSpace Type- Office
For Lease- $18.00/SF/YR
8 spaces available / 1,468 - 18,461 SF -
36 Oswego St, Baldwinsville, NYProperty Type- Mixed Use
For Sale- $1,000,000
Built in 1960 / Property size 14,310 SF -
3535 Walters Road, East Syracuse, Syracuse, NYProperty Type- Retail
For Sale- $4,900,000
Built in 2008 / Property size 16,400 SF -
409 Grand Ave, Skunk City, Syracuse, NYProperty Type- Other
For Sale- $219,000
Built in 1960 / Property size 4,016 SF -
100 Dewey Ave, East Syracuse, Fayetteville, NY -
1417-31 Valley Drive, North Valley, Syracuse, NYProperty Type- Retail
For Sale- $699,000
Built in 1935 / Property size 11,320 SF -
100 East Washington St Syracuse, Downtown Syracuse, Syracuse, NYSpace Type- Office
For Lease- $16.00/SF/YR
1 space available / 3,034 SF -
8574 and 8568 Brewerton Road, Cicero, NYProperty Type- Industrial
For Sale- $3,500,000
Property size 31,899 SF -
309 Vine St, Liverpool, NY -
300 East Washington Street, Downtown Syracuse, Syracuse, NYSpace Type- Restaurant
For Lease- $12.92/SF/YR
1 space available / 2,880 SF -
500 Plum Street, Lakefront, Syracuse, NYSpace Type- Office
For Lease- $20.00/SF/YR
1 space available / 7,054 SF -
250 Harrison Street, Downtown Syracuse, Syracuse, NYSpace Type- Retail
For Lease- $16.00/SF/YR
1 space available / 2,302 SF -
301 South Salina Street, Downtown Syracuse, Syracuse, NYSpace Type- Retail
For Lease- $20.00/SF/YR
1 space available / 6,000 SF -
187 Northern Concourse, North Syracuse, NY -
215 Greenfield Pkwy, Galeville, Liverpool, NYSpace Type- Office
For Lease Contact for pricing -
224 Harrison St, Suite 210, Syracuse, NYJF Real Estate - ShareCuse
JF Real EstateSpace Type- Private Offices
For Lease-
From $450/month
Space for 1 to 3 people -
3522 James Street, Eastwood, Syracuse, NYSpace Type- Office
For Lease Contact for pricing -
225 Greenfield Pkwy, Galeville, Liverpool, NYSpace Type- Office
For Lease- $17.00/SF/YR
2 spaces available / 1,490 - 3,305 SF -
210 Hamilton Street, Far Westside Syracuse, Syracuse, NYProperty Type- Other
For Sale- $2,300,000
Property size 1,625 SF -
4914 W Genesee St, Fairmount, Camillus, NYSpace Type- Office
For Lease Contact for pricing -
4709 Crossroads Park Drive, North Syracuse, Liverpool, NYSpace Type- Office
For Lease Contact for pricing -
36 Oswego St, Baldwinsville, NYSpace Type- Retail
For Lease- $18.00/SF/YR
1 space available / 3,000 SF -
333 West Washington Street, Downtown Syracuse, Syracuse, NYSpace Type- Office
For Lease- $22.00/SF/YR
1 space available / 3,041 SF -
4902 W Genesee St, Fairmount, Syracuse, NYSpace Type- Office
For Lease Contact for pricing -
3522 James St, Eastwood, Syracuse, NYSpace Type- Office
For Lease Contact for pricing -
3522 James St, Eastwood, Syracuse, NYSpace Type- Office
For Lease Contact for pricing -
7000 East Genesee Street, East Syracuse, Fayetteville, NY -
109 South Warren Street, Downtown Syracuse, Syracuse, NY -
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116 Boss Rd, East Syracuse, Syracuse, NYSpace Type- Office
For Lease- $10.00/SF/YR
1 space available / 970 SF -
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4914 W Genesee St, Fairmount, Camillus, NY -
110 Townsend St S, Downtown Syracuse, Syracuse, NYSpace Type- Industrial
For Lease- $6.50/SF/YR
1 space available / 13,134 SF -
739 Irving Avenue, University Hill, Syracuse, NY -
530 State Fair Blvd, Lakefront, Syracuse, NYSpace Type- Industrial
For Lease- $6.00 - $6.50/SF/YR
1 space available / 15,000 SF -
3522 James St, Eastwood, Syracuse, NYSpace Type- Office
For Lease Contact for pricing -
224 Harrison Street, Downtown Syracuse, Syracuse, NYSpace Type
- Office, Restaurant
For Lease- $12.50 - $16.00/SF/YR
6 spaces available / 500 - 7,677 SF