Orangeburg County, SC Commercial Real Estate for Lease and Sale
Explore 51 listing(s) of commercial real estate in Orangeburg County, SC to find the best space for your business.
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1000 Gilway St, Holly Hill, SCProperty Type- Industrial
For Sale- $1,000,000
Property size 36,822 SF -
1911 Old Edisto Drive, Orangeburg, SCProperty Type- VacantLand
For Sale- $495,000
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1175 Cook Road, Brookdale, Orangeburg, SC -

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Cannon Bridge Rd, Cope, Cordova, SCProperty Type- VacantLand
For Sale- $27,950
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Branchdale Hwy, Vance, Holly Hill, SCProperty Type- VacantLand
For Sale- $129,000
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Shellie Jean Road, Cordova, SCProperty Type- VacantLand
For Sale- $28,750
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Good Farm Rd, Holly Hill, Holly HIll, SCProperty Type- VacantLand
For Sale- $6,700,000
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389 Stonewall Jackson Street Southwest, Orangeburg, SC -
2076 Columbia Road, Orangeburg, SC -
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1032 Chestnut Street, Orangeburg, SCSpace Type- Retail
For Lease- $20.00/SF/YR
1 space available / 4,000 SF -
1490 Chestnut Street, Orangeburg, SCSpace Type- Retail
For Lease- $17.00/SF/YR
1 space available / 5,363 SF -
1214 Saint Matthews Rd, Orangeburg, SCSpace Type- Retail
For Lease- $10.00/SF/YR
1 space available / 4,550 SF -
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Saint Matthews Rd NE, Orangeburg, SCSpace Type- Office
For Lease- $24.00/SF/YR
1 space available / 2,695 SF -
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2722, 2724, 2725, 2727, and 2733 West Cleveland Street | 460 Railroad Ave may be merged by subsequent Addenda, Elloree, SCProperty Type- Office
For Sale- $861,000
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3599 Saint Matthews Rd, Orangeburg, SCProperty Type- Retail
For Sale- Subject To Offer
Property size 4,869 SF -
8636 Old State Rd, Holly Hill, SCSpace Type- Office
For Lease- $12.00 - $15.00/SF/YR
5 spaces available / 549 - 2,509 SF -
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Hwy 601 St Matthews Road, Brookdale, Orangeburg, SC -
Cannon Bridge & Cordova Road, Edisto, Orangeburg, SC -
2718 Old State Rd, Cameron, SCProperty Type- VacantLand
For Sale- $105,000
Property size 1.41 Acre -
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Rowesville Rd, Orangeburg, SCProperty Type- Other
For Sale- Subject To Offer
Property size 1 SF -
8618 Old State Rd, Holly Hill, SCProperty Type- Office
For Sale- $225,000
Built in 1950 / Property size 3,350 SF -
8955 Old State Rd, Holly Hill, SCProperty Type- VacantLand
For Sale- $550,000
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2710 Old State Rd, Cameron, SCProperty Type- VacantLand
For Sale- $285,000
Property size 3.88 Acre -
2785 St. Matthews Road NE, Orangeburg, SCProperty Type- VacantLand
For Sale- $419,000
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295 Prosperity Dr, Orangeburg, SCProperty Type- Industrial
For Sale- $2,500,000
Property size 40,500 SF -
2423 Homestead Road, Bowman, SCProperty Type- Industrial
For Sale- $2,100,000
Property size 9,600 SF -
Hannah Drive, Santee, SC -
1260 Ridgewood Drive, Orangeburg, SCProperty Type- Retail
For Sale- $675,000
Property size 5,000 SF -
8099 Five Chop Road, Vance, Santee, SC -
306 Woodrow St @ Hwy 321, Neeses, SC -
5243 Vance Rd, Bowman, SC -
Garland Rd, Rowesville, SCProperty Type- VacantLand
For Sale- $250,000
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125 Kinard St, Orangeburg, SC -
144 Old Elloree Rd, Wilkinson Heights, Orangeburg, SC -
328 John C Calhoun, Orangeburg, SCProperty Type- Industrial
For Sale- $1,150,000
Property size 17,960 SF -
2850 Magnolia Street, Brookdale, Orangeburg, SC -
1535 John C. Calhoun Drive, Orangeburg, SC -
00 Willington Road , Orangeburg, SCProperty Type- VacantLand
For Sale- $517,860
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144 Old Elloree Road, Wilkinson Heights, Orangeburg, SC -
1214 Saint Matthews Rd, Orangeburg, SCSpace Type- Retail
For Lease- $10.00/SF/YR
1 space available / 6,000 SF -
960 Middleton Street, Orangeburg, SC -
1000 Southern Patio Parkway, Rowesville, SCSpace Type- Industrial
For Lease- $2.85 - $4.00/SF/YR
1 space available / 326,000 SF