Mayo Clinic Square

600 Hennepin Avenue, Minneapolis, MN 55403

Property Information

  • For Lease $18.00 - $22.00/SF/YR
  • Property Type Office - General Office
  • Property Size 217,354 SF
  • Lot Size 2.61 Acre
  • Parking Spaces Avail. 673
  • Parking Ratio 3.10 / 1,000 SF
  • Property Tenancy Multi-Tenant
  • Building Class A
  • Year Built 2004
  • Date Updated May 25, 2026

Description

Mayo Clinic Square is a 217,354-square-foot Class A office building situated on a 2.61-acre lot in Downtown Minneapolis. Built in 2004, the property provides convenient on-site parking with 673 spaces, offering a parking ratio of 3.1 per 1,000 square feet. Designed to accommodate modern office needs, this premier office space delivers an exceptional environment for tenants seeking a professional setting in the heart of the city.

Positioned in Downtown Minneapolis, the property is surrounded by a variety of amenities and transportation options. Dining establishments such as Gold Room and Gluek's Restaurant & Bar are just steps away, while nearby hotels like the Loews Minneapolis Hotel and Embassy Suites provide convenient accommodations for visiting clients. Public transit is easily accessible, with the Warehouse District/Hennepin Avenue station approximately 0.1 miles away, and parking facilities such as Butler Park just 0.06 miles from the building. The area also offers proximity to educational institutions, including the University of St. Thomas, which is about 0.35 miles away.

4 Spaces Available

#100

Space Type

Restaurant

Lease Rate

$18.00 - $22.00/SF/YR

Total Space

8,453 SF

Additional Rent

$16.42/SF/YR

Divisible Space

8,453 - 8,453 SF

Available Date

Immediate

Lease Type

NNN

Renewal Option

Yes

Sublease

No

#110

Space Type

Restaurant

Lease Rate

$18.00 - $22.00/SF/YR

Total Space

10,337 SF

Additional Rent

$16.42/SF/YR

Divisible Space

10,337 - 10,337 SF

Available Date

Immediate

Lease Type

NNN

Renewal Option

Yes

Sublease

No

#180

Space Type

Retail

Lease Rate

Contact for pricing

Total Space

1,834 SF

Floor

1

Divisible Space

1,834 - 1,834 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

#190

Space Type

Retail

Lease Rate

Contact for pricing

Total Space

1,048 SF

Additional Rent

$17.00/SF/YR

Floor

1

Divisible Space

1,048 - 1,048 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

Contacts

Jon Dahl

Jones Lang LaSalle

Teig Hutchison

Jones Lang LaSalle

Brent Robertson

Jones Lang LaSalle

Sabine Shea

Assembly Commercial Real Estate Advisors

Merrie Sjogren

Assembly Commercial Real Estate Advisors

Location

Located at 600 Hennepin Avenue, Minneapolis, MN 55403, this property is part of the Downtown Minneapolis neighborhood and Minneapolis St Paul market.

Contact Mayo Clinic Square
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