Up to 40,702 SF Available for Lease - Prime Cortex Location

4300 Duncan Avenue, St. Louis, MO 63110

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Property Information

  • For Lease Contact for pricing
  • Property Type Office - General Office
  • Year Built 2008
  • Date Updated May 21, 2026

Description

Architecturally striking and built to Fortune 500 standards, 4300 Duncan is a future-forward workplace with technology and collaboration at its core. Infused with equal parts productivity and lifestyle, 4300 Duncan is situated at the center of the Cortex Innovation District; a gravitational hub for top global talent.

 

• 9,438 SF - Features include:
- Second floor vacancy
- Excellent existing conditions
- Two common conference rooms and breakroom
- Available now


• 31,264 SF - Features include:
- Top floor vacancy
- Full floor opportunity
- Excellent existing conditions
- 31 private offices and an IT room
- Building signage opportunity
- Available 5/1/2026

Highlights

  • Adjacent garage and surface parking
  • Building and monument signage available
  • Building conference and collaboration spaces
  • Full floor opportunity available
  • Plentiful visitor parking

1 Space Available

Space Available

Space Type

General Office

Lease Rate

Contact for pricing

Total Space

31,264 SF

Divisible Space

9,438 - 31,264 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

Build Type

Full build out

Contacts

Rebekah Bahn Kingston

Colliers

Tony Kennedy

Colliers

Location

Located at 4300 Duncan Avenue, St. Louis, MO 63110, this property is part of the Central West End Saint Louis neighborhood and St Louis market.

  • 73/100 Very Walkable
  • 59/100 Good Transit
  • 62/100 Bikeable
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Contact Up to 40,702 SF Available for Lease - Prime Cortex Location
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