The 222 Building

222 South Central Avenue, St. Louis, MO 63105

Property Information

  • For Lease $26.50 - $27.50/SF/YR
  • Property Type Office - General Office
  • Property Size 127,000 SF
  • Lot Size 0.92 Acre
  • Parking Spaces Avail. 381
  • Parking Ratio 3.00 / 1,000 SF
  • Property Tenancy Multi-Tenant
  • Building Class B
  • Year Built 1968
  • Date Updated Apr 9, 2026

Description

The 222 Building, a 127,000-square-foot general office property, sits on a 0.92-acre lot in St. Louis and includes 381 parking spaces with a parking ratio of 3 spaces per 1,000 square feet. Originally constructed in 1968, this Class B office building offers tenants a professional setting for business operations, with convenient on-site parking enhancing accessibility for employees and visitors alike.

Situated near Clayton, the property benefits from a vibrant business district and a wealth of nearby amenities. Dining options such as Copia, Caf? la Vie, and Panera Bread are all within 0.25 miles, while hotels including AC Hotel St. Louis Clayton and Clayton Plaza Hotel are within 0.2 miles. For public transit users, the Clayton Metrolink Parking Garage is approximately 0.07 miles away, and cultural destinations like the Missouri History Museum are under 3 miles from the property. Nearby educational institutions, including Clayton High School and Washington University, further enhance the appeal of the area.

8 Spaces Available

#110

Space Type

General Office

Lease Rate

$26.50/SF/YR

Total Space

5,770 SF

Divisible Space

5,770 - 5,770 SF

Available Date

Immediate

Lease Type

Full Service

Renewal Option

Yes

Sublease

No

#207

Space Type

General Office

Lease Rate

Contact for pricing

Total Space

1,100 SF

Divisible Space

1,100 - 1,100 SF

Available Date

Immediate

Lease Type

Full Service

Renewal Option

Yes

Sublease

No

#300

Space Type

General Office

Lease Rate

$26.50/SF/YR

Total Space

3,267 SF

Divisible Space

3,267 - 3,267 SF

Available Date

Immediate

Lease Type

Full Service

Renewal Option

Yes

Sublease

No

#400

Space Type

General Office

Lease Rate

$27.50/SF/YR

Total Space

3,346 SF

Divisible Space

3,346 - 3,346 SF

Available Date

Immediate

Lease Type

Full Service

Renewal Option

Yes

Sublease

No

Spec Suite

  

#700

Space Type

General Office

Lease Rate

$26.50/SF/YR

Total Space

6,095 SF

Divisible Space

6,095 - 6,095 SF

Available Date

Immediate

Lease Type

Full Service

Renewal Option

Yes

Sublease

No

Contacts

Rick Messey

CBRE

Kori Gibbons

CBRE

Location

Located at 222 South Central Avenue, St. Louis, MO 63105, this property is part of the Clayton neighborhood and St Louis market.

Contact The 222 Building
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