321 Main Street Seneca SC

321 Main Street, Seneca, SC 29678

Property Information

  • For Lease $20.00/SF/YR
  • Property Type Retail - Street Retail
  • Property Size 5,500 SF
  • Units 1
  • Date Updated May 12, 2026

Description

Downtown Seneca, SC.For Lease a 2,600 SF retail space located at 321 Main Street in the heart of downtown Seneca. The space is in excellent condition and can be easily adapted for use as a restaurant, bar, office or retail. One of two commercial units in a building set in Historic Downtown Seneca. This location offers 34’ frontage on Main Street with street-to-street access to the rear on West North First Street. This space offers an open floor plan with restrooms and storage in the back. The property is located inside city limits and is zoned commercial by the city of Seneca. There is ample parking and a municipal lot directly across Main. The unit is fully heated and air-conditioned with private entrance and restroom facilities. The asking price is $20/SF NNN. This location is close to all city activities including the popular Ram Cat Alley, the new Performing Arts Center and open-air amphitheater. Contact Listing agents with any interest or to schedule a showing.

1 Space Available

321 Main St

Space Type

Street Retail

Lease Rate

$20.00/SF/YR

Total Space

2,600 SF

Divisible Space

2,600 - 2,600 SF

Available Date

Immediate

Lease Type

NNN

Renewal Option

Yes

Sublease

No

For Lease a 2,600 SF retail space located at 321 Main Street in the heart of downtown Seneca. The space is in excellent condition and can be easily adapted for use as a restaurant, bar, office or retail. One of two commercial units in a building set in Historic Downtown Seneca. This location offers 34’ frontage on Main Street with street-to-street access to the rear on West North First Street. This space offers an open floor plan with restrooms and storage in the back. The property is located inside city limits and is zoned commercial by the city of Seneca. There is ample parking and a municipal lot directly across Main. The unit is fully heated and air-conditioned with private entrance and restroom facilities. The asking price is $20/SF NNN. This location is close to all city activities including the popular Ram Cat Alley, the new Performing Arts Center and open-air amphitheater. Contact Listing agents with any interest or to schedule a showing.

Contacts

Eddie Smith

McCoy Wright

Location

Located at 321 Main Street, Seneca, SC 29678, this property is part of the Seneca neighborhood and Greenville market.

Contact Listing Broker
Eddie Smith

McCoy Wright

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