721 SE Main St | Retail Development

721 SE Main Street, Simpsonville, SC 29680

  • For Lease Contact for pricing
  • Property Type Retail - Strip
  • Property Size 17,500 SF
  • Lot Size 1.65 Acre
  • Property Tenancy Multi-Tenant
  • Year Built 2025
  • Date Updated Jul 22, 2025
Reedy River Retail at SVN | Palmetto is pleased to offer up to ±7,500 SF of retail space for lease alongside Pro-Fitness Gym at 721 SE Main St. in Simpsonville, SC. Located just off I-385 (±75,700 VPD) and Fairview Rd (±30,600 VPD), the sitebenefits from excellent visibility and accessibility, drawing from both the rapidly growing residential base of Simpsonville and the broader Greenville MSA. The space is sub-dividable for qualified users and will be delivered early 2026. This development benefits from flexible zoning that accommodates a variety of retail, medical, and service-oriented uses—ideal for tenants seeking long-term adaptability. The project will benefit from full access from SE Main St., secondary access via Powderhorn Rd, and proximity to established traffic drivers—making this a great location within a high demand market.Reedy River Retail at SVN | Palmetto is pleased to offer up to ±7,500 SF of retail space for lease alongside Pro-Fitness Gym at 721 SE Main St. in Simpsonville, SC. Located just off I-385 (±75,700 VPD) and Fairview Rd (±30,600 VPD), the site benefits from excellent visibility and accessibility, drawing from both the rapidly growing residential base of Simpsonville and the broader Greenville MSA. The space is sub-dividable for qualified users and will be delivered early 2026. This development benefits from flexible zoning that accommodates a variety of retail, medical, and service-oriented uses—ideal for tenants seeking long-term adaptability. The project will benefit from full access from SE Main St., secondary access via Powderhorn Rd, and proximity to established traffic drivers—making this a great location within a high demand market.
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Reach out to the broker for more info on lease terms and amenities

Highlights

  • Parking: ±60 spaces
  • Traffic: SE Main St (±18,400 VPD), I-385 (±75,700 VPD) and Fairview Rd (±30,600 VPD)
  • Type: Multi-Tenant Retail
  • Zoning: BG

Spaces Available

Contacts

broker

SVN | BlackStream

Location

Getting Around

  • Walk Score ®

    37/100 Car-Dependent
  • Bike Score ®

    27/100 Somewhat Bikeable
Powered by Walk Score ®
  • City Simpsonville, SC
  • Neighborhood Simpsonville
  • Zip Code 29680
  • Market Greenville

Points of Interest

  • Mike & Jack's

    0.49 miles

  • Exxon

    0.56 miles

  • Murphy USA

    0.57 miles

  • Spinx

    1.12 miles

  • 7-Eleven

    1.14 miles

  • EVgo

    1.14 miles

  • QuikTrip

    1.24 miles

  • Circle K

    1.59 miles

  • Citgo

    1.81 miles

  • Stop A Minit

    1.98 miles

  • Amenities parking

    0.88 miles

  • Amphitheatre Work Parking

    1.36 miles

  • Center Parking

    3.22 miles

  • Trail Access Parking

    3.48 miles

  • Pool and Playground Parking Only

    5.26 miles

  • True Health Parking

    5.70 miles

  • Trailer Parking

    6.51 miles

  • Swamp Rabbit Trail Parking

    6.51 miles

  • AAA Parking

    7.05 miles

  • Coach House Restaurant

    0.13 miles

  • Milano Pizzaria

    0.18 miles

  • Carolina Fine Food

    0.23 miles

  • McDonald's

    0.25 miles

  • Outback Steakhouse

    0.31 miles

  • Five Guys

    0.34 miles

  • Waffle House

    0.36 miles

  • Taco Bell

    0.38 miles

  • Pizza Hut

    0.39 miles

  • Subway

    0.42 miles

  • Big Lots

    0.34 miles

  • Ingles

    0.41 miles

  • Kohl's

    0.45 miles

  • Walmart Supercenter

    0.61 miles

  • ALDI

    0.65 miles

  • Belk

    0.77 miles

  • Food Lion

    1.03 miles

  • Target

    1.14 miles

  • Ross

    1.21 miles

  • TJ Maxx

    1.23 miles

Frequently Asked Questions

How much does retail space at 721 SE Main Street cost?

The price for retail space for lease at 721 SE Main Street is available upon request. Pricing of commercial spaces is largely dependent on things like location — especially proximity to areas that can be easily reached by car or public transit or enjoy high foot traffic — the overall size, features and condition of the space, and the lease structure. Safety and security in the area can also play an important role in choosing the most suitable retail space for a business.

What kind of retail space can I rent at 721 SE Main Street?

The property has 7,500 square feet of rentable Strip space. Rental opportunities here are available under NNN lease terms.

The building accommodates a Multi-Tenant lease setup. Use the contact form at the top of this page to schedule a tour of the property with a broker and get further details on this listing.

How many parking spots are available at 721 SE Main Street?

Reach out to the listing broker for more information on vehicle access and parking options at or near this property, as well as additional amenities that complement the retail experience at 721 SE Main Street. You can find 1 fuel station(s) within a 0.5-mile radius.

Are there any potentially competing retail businesses in the area?

Yes, there are 5 spaces zoned for retail use within a 0.5-mile radius of 721 SE Main Street.

Is 721 SE Main Street located in a popular area for retail businesses?

The property is part of Simpsonville.

Looking for more in-depth information on this property?

Looking for more in-depth information on this property? Find property characteristics, ownership, tenant details, local market insights and more. Unlock data on CommercialEdge.

Contact Listing Broker
broker

SVN | BlackStream

  1. 1Main information
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