Prime Medical Professional Space | For Lease

1111 S Jefferson St, Roanoke, VA 24016

  • For Lease $13.50/SF/YR
  • Property Type Office - Medical Office
  • Property Size 9,152 SF
  • Units 2
  • Lot Size 0.7 Acre
  • Building Class B
  • Year Built 1981
  • Date Updated Jul 10, 2025
1111 S Jefferson Street is a prominently located two-story office building situated just south of downtown in the Old Southwest neighborhood. This highly visible property offers convenient access to major routes, including I-581 and I-81, and is less than one mile from Carilion Roanoke Memorial Hospital and the growing Carilion/VT innovation campus. Surrounded by a mix of professional, medical, and residential development, the building is ideally positioned for businesses seeking a central and accessible location. Tenants will benefit from proximity to downtown amenities, including restaurants, shops, and parks, as well as 38 on-site parking spaces. This space is well-suited for medical, administrative, or professional office use, offering a strategic address within a dynamic and evolving area of Roanoke.Presented for lease by Evan Zachman and Stephen Pendergrass of Poe & Cronk Real Estate Group - 1111 Jefferson St. features 4,567± SF of move-in ready medical/professional office space available for lease located on the ground level. This professionally maintained building offers a functional and flexible layout ideal for medical, administrative, or professional office users. The space features a welcoming reception area, multiple private offices or exam rooms, conference space, restrooms, and 19 parking spaces.
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Highlights

  • Ample parking for tenants and guests
  • Flexible floor plans to suit various business needs
  • High visibility and easy access for customers
  • Modern and well-maintained building
  • Prime location in Roanoke, VA

Spaces Available

Contacts

broker
Evan Zachmann

Poe & Cronk Real Estate Group

Location

Getting Around

  • Walk Score ®

    75/100 Very Walkable

  • Transit Score ®

    46/100 Some Transit

  • Bike Score ®

    82/100 Very Bikeable
Powered by Walk Score ®
  • City Roanoke, VA
  • Zip Code 24016

Points of Interest

  • Citgo

    0.47 miles

  • Kroger

    1.03 miles

  • Exxon

    1.65 miles

  • Valero Fuel

    1.72 miles

  • Walmart

    1.92 miles

  • Speedway

    2.25 miles

  • 7-Eleven

    4.26 miles

  • ChargePoint

    5.88 miles

  • Tesla Supercharger

    7.80 miles

  • Carilion Community Hospital Parking

    0.25 miles

  • Elmwood Lot

    0.37 miles

  • Church Avenue Garage

    0.54 miles

  • Center in the Square Garage

    0.60 miles

  • Rivers Edge North Park Parking Access

    0.66 miles

  • Five Market Street

    0.69 miles

  • Carilion Clinic Family Medicine SE Parking

    1.73 miles

  • Fishburn Park Parking

    2.46 miles

  • East Gate Park Parking

    2.52 miles

  • Murray Run Greenway Trailhead Parking

    2.61 miles

  • King George Inn Bed & Breakfast

    0.38 miles

  • Hampton Inn & Suites Roanoke - Downtown

    0.51 miles

  • SpringHill Suites Roanoke

    0.55 miles

  • Roanoke Boutique Hotel

    0.66 miles

  • The Hotel Roanoke & Conference Center, Curio Collection by Hilton

    0.80 miles

  • Comfort Inn - Roanoke Civic Center

    1.30 miles

  • Econo Lodge Civic Center

    1.42 miles

  • Holiday Inn Express & Suites Roanoke Civic Center

    1.52 miles

  • Quality Inn

    2.70 miles

  • Hilton Garden Inn

    2.92 miles

  • Lews

    0.11 miles

  • Evie's Bistro and Bakery

    0.37 miles

  • Inka Peruvian Grill

    0.41 miles

  • Moe's Southwest Grill

    0.43 miles

  • Big Valley Barbecue

    0.47 miles

  • Sidecar

    0.49 miles

  • Delicias Boricuas

    0.50 miles

  • Stock Cafe and Bar

    0.50 miles

  • Texas Tavern

    0.52 miles

  • Macado's

    0.52 miles

  • Viaud School

    0.18 miles

  • Jefferson College of Health Sciences

    0.23 miles

  • Radford University Carilion

    0.26 miles

  • Virginia Tech Carilion Research Institute

    0.38 miles

  • Highland Park Elementary School

    0.47 miles

  • Roanoke Higher Education Center

    0.79 miles

  • Rivermont Southwest Roanoke School

    0.87 miles

  • Stonewall Jackson Junior High School

    0.88 miles

  • Our Lady of Nazareth School

    0.92 miles

  • Saint Andrews Elementary School

    1.02 miles

  • Mike's Country Market

    4.42 miles

Frequently Asked Questions

What is the price for renting office space at Prime Medical Professional Space | For Lease?

The price for office space here is $13.50/SF/YR.

What type of office space is available to lease at Prime Medical Professional Space | For Lease?

In total, there is 4,567 square feet of office space for lease here. Availability at this location includes 1 Office space.

Is Prime Medical Professional Space | For Lease suitable for a small business?

Yes, availabilities here may be suitable for small businesses with 1 office space under 5,000 square feet available.

Does Prime Medical Professional Space | For Lease have parking?
Parking information for the property isn't currently listed. However, other nearby parking options include Carilion Community Hospital Parking, located 0.25 miles away, and Elmwood Lot, which is 0.37 miles away.
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Contact Listing Broker
broker
Evan Zachmann

Poe & Cronk Real Estate Group

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