St Lucie County, FL Commercial Real Estate for Lease and Sale
Explore 216 listing(s) of commercial real estate in St Lucie County, FL to find the best space for your business.
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SW Becker Rd & SW Village Pkwy, Southern Grove, Port St. Lucie, FL -
10570 South Federal Highway, Port St. Lucie, FLSpace Type- Private Offices
For Lease-
From $545/month
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673 NW Enterprise Dr, St. Lucie West, Port St. Lucie, FL -
5021 Turnpike Feeder Rd, Lakewood Park, Fort Pierce, FL -

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501 Southwest Port Saint Lucie Boulevard, Oak Hammock, Port St. Lucie, FLSpace Type- Office
For Lease- $24.00/SF/YR
1 space available / 1,000 SF -
7528 US-1, Spanish Lakes, Port St. Lucie, FLSpace Type- Retail
For Lease- $21.00/SF/YR
4 spaces available / 1,283 - 1,750 SF -
3201 SW PORT ST LUCIE, Villas of Windmill Point, Port St. Lucie, FL -
1880 SW Fountainview Blvd., The Belmont at St Lucie West, Port St. Lucie, FL -
247-295 Port St. Lucie Boulevard, Thornhill, Port St. Lucie, FL -
1851 N US Highway 1, Paradise Park, Fort Pierce, FLSpace Type- Retail
For Lease- $20.00 - $21.00/SF/YR
2 spaces available / 1,365 - 2,400 SF -
2250 SW Gatlin Blvd, Portofino Isles, Port Saint Lucie, FL -
SR 70 & Florida Turnpike Interchange, Virginia Park, Fort Pierce, FL -
130 S Indian River Dr, Downtown Fort Pierce, Fort Pierce, FLSpace Type- Office
For Lease- $18.00/SF/YR
1 space available / 1,085 SF -
2195 Kings Hwy, Crouchville Acres, Fort Pierce, FLProperty Type- VacantLand
For Sale- $895,000
Property size 2.24 Acre -
905 E Prima Vista Blvd, River Park, Port St. Lucie, FL -
408 Avenue E, Avenue D, Fort Pierce, FLProperty Type- VacantLand
For Sale- $550,000
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826 NE Camino St, River Park, Port St. Lucie, FL -
3229 South US Highway 1, Windsong Village, Fort Pierce, FLProperty Type- VacantLand
For Sale- $750,000
Property size 0.68 Acre -
605 NW Prima Vista Blvd, River Park, Port St. Lucie, FL -
9100-9198 US Highway 1, Port St. Lucie Industrial Park, Port St. Lucie, FL -
3001 SW Port St Lucie Blvd, Parks Edge, Port St. Lucie, FLProperty Type- Retail
For Sale- $4,580,000
Built in 2018 / Property size 7,250 SF -
1290 SE Port St Lucie Blvd, Sandpiper Bay, Port Saint Lucie, FL -
US-1 & Saegar Avenue, White City, Port St Lucie, FL -
2501 Virginia Avenue, Cortez Estates, Fort Pierce, FLSpace Type- Office
For Lease- $44.00/SF/YR
1 space available / 1,200 SF -
1901-1905 S. 25th Street, Dreamland Park, Fort Pierce, FLSpace Type- Office
For Lease- $17.00 - $19.00/SF/YR
3 spaces available / 680 - 1,642 SF -
16050 Orange Ave, Green Swamp Preserve, Fort Pierce, FLProperty Type- Industrial
For Sale- $3,299,000
Built in 1986 / Property size 15,148 SF -
202-204 SW Port Street Lucie Blvd, Thornhill, Port St. Lucie, FL -
US-1 & Saegar Avenue, Lake Charles, Port St Lucie, FL -
2221 W Midway Road, White City, Fort Pierce, FLProperty Type- VacantLand
For Sale- $549,000
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904 Valley Ln, Paradise Park, Fort Pierce, FLProperty Type- VacantLand
For Sale- $249,900
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1125 SE Port St. Lucie Blvd, Morningside, Port St. Lucie, FLSpace Type- Retail
For Lease- $20.00 - $27.08/SF/YR
2 spaces available / 1,000 - 2,400 SF -
5780 S US Highway 1, Indian River Estates, Fort Pierce, FL -
116 Hartman Road, Dreamland Park, Fort Pierce, FLProperty Type- VacantLand
For Sale- $299,000
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Becker Rd & I-95 Port St Lucie, Tesoro, Port St. Lucie, FL -
11530 SW Village Pkwy, Southern Grove, Port St. Lucie, FL -
1860 Southwest Fountainview Boulevard #100, Port St. Lucie, FLSpace Type- Private Offices
For Lease-
From $625/month
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SW Becker Rd & SW Village Pkwy, Southern Grove, Port St. Lucie, FL -
1750 South Kings Hwy, Crouchville Acres, Fort Pierce, FLProperty Type- VacantLand
For Sale- $9,250,000
Property size 34.07 Acre -
Lamont Rd, Kings Highway Industrial Park, Fort Pierce, FLProperty Type- VacantLand
For Sale- $6,500,000
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12050 SW Tom Mackie Blvd, Southern Grove, Port St. Lucie, FLSpace Type- Industrial
For Lease- $11.00 - $20.00/SF/YR
7 spaces available / 6,017 - 127,634 SF -
7805 N Orange Ave, Fort Pierce West, Fort Pierce, FL -
3203 SW Port St. Lucie Boulevard, Gatlin, Port St. Lucie, FLSpace Type- Retail
For Lease- $22.00/SF/YR
3 spaces available / 900 - 1,256 SF -
1631 SW Gatlin Blvd, Oak Hammock, Port St. Lucie, FLSpace Type- Office
For Lease- $25.00/SF/YR
1 space available / 1,288 SF -
Midway Road, White City, Fort Pierce, FL -
2250 SW Gatlin Boulevard, Newport Isle, Port St. Lucie, FL -
1333 St Lucie W Blvd, St. Lucie West, Port St. Lucie, FL -
Tilton Road, Spanish Lakes, Port St. Lucie, FL -
200 NW PEACOCK BLVD, St. Lucie West, Port St. Lucie, FL -
10753 S US Highway 1, Sandpiper Bay, Port Saint Lucie, FL -
2155 Settle Avenue, Reserve Commerce Park, Port St. Lucie, FLSpace Type- Industrial
For Lease- $17.00 - $19.00/SF/YR
2 spaces available / 850 - 1,700 SF -
130 S Indian River Drive, Downtown Fort Pierce, Fort Pierce, FLProperty Type- Office
For Sale- $425,000
Property size 1,085 SF -
3112 Oleander Ave, Maravilla Estates, Fort Pierce, FLProperty Type- VacantLand
For Sale- $549,500
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7528 US-1, Spanish Lakes, Port St. Lucie, FL