South Carolina Commercial Real Estate for Lease and Sale
Explore 3,709 listing(s) of commercial real estate in South Carolina to find the best space for your business.
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1050 Tenor Ln, Summerton, SCProperty Type- VacantLand
For Sale- $28,175
Built in 1980 / Property size 732 SF -
208 West Hampton Avenue 1st Floor, Sumter, SCSpace Type- Private Offices
For Lease-
From $319/month
Space for 1 to 15 people -
245 Crystal Dr, Mount Pleasant, SCProperty Type- VacantLand
For Sale- $725,000
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Calhoun Memorial Hwy, Easley, SC -

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5935 Rivers Avenue, North Charleston, SCSpace Type- Industrial
For Lease- $12.00 - $14.00/SF/YR
5 spaces available / 6,820 - 27,950 SF -
Knox Avenue, North Augusta, SCProperty Type- VacantLand
For Sale- Subject To Offer
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4500 Leeds Ave, North Charleston, SC -
236 Union Street, Downtown Spartanburg, Spartanburg, SCSpace Type- Office
For Lease- $10.00/SF/YR
1 space available / 23,331 SF -
4330 Cheyenne St, North Charleston, SCSpace Type- Industrial
For Lease- $13.50/SF/YR
1 space available / 1,420 SF -
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Bedford Rd, Meadow Lake, Columbia, SCProperty Type- Other
For Sale- $1,306,000
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4100 River Neck Road, Florence, SCSpace Type- Land
For Lease Contact for pricing -
1445 Greenleaf Road, Silver Hill - Magnolia, Charleston, SCSpace Type- Industrial
For Lease- $9.50/SF/YR
1 space available / 23,537 SF -
00 Highway 29 S, Homeland Park, Anderson, SCProperty Type- VacantLand
For Sale- $950,000
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23 Main Street, Suite 303, Hilton Head Island, SCProperty Type- Office
For Sale- $375,000
Property size 1,213 SF -
55 East Camperdown Way, Downtown Greenville, Greenville, SCSpace Type- Office
For Lease- $28.00/SF/YR
1 space available / 63,624 SF -
6406 Garners Ferry Road, Brandon Acres, Columbia, SC -
5101 Ashley Phosphate Rd, North Charleston, SCSpace Type- Retail
For Lease- $15.00 - $40.00/SF/YR
10 spaces available / 1,200 - 40,704 SF -
729 Anderson Street, Belton, SCSpace Type- Retail
For Lease- $8.00 - $12.00/SF/YR
1 space available / 6,534,000,000 SF -
107 West Church Street, Batesburg - Leesville, Batesburg-Leesville, SC -
Bickley Rd, Irmo, SCProperty Type- Other
For Sale- $440,000
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8201 Augusta Rd, Golden Grove, Piedmont, SC -
8085 Rivers Ave, North Charleston, SCSpace Type- Office
For Lease- $13.50 - $16.50/SF/YR
1 space available / 79,997 SF -
42 Mingo Dr, Ehrhardt, SCProperty Type- VacantLand
For Sale- $23,750
Built in 1992 / Property size 784 SF -
233 W Lucas St, Florence, SCProperty Type- Retail
For Sale- $998,000
Built in 2004 / Property size 9,476 SF -
1000 2nd Avenue South, North Myrtle Beach, SCSpace Type- Private Offices
For Lease-
From $319/month
Space for 1 to 15 people -
7329 Spa Rd, North Charleston, SCProperty Type- Industrial
For Sale- $1,999,999
Built in 1976 / Property size 7,800 SF -
00 Dark Indigo Ln, Graniteville, SCProperty Type- VacantLand
For Sale- $950,000
Built in 2017 / Property size 87,450 SF -
1201 Woods Chapel Rd, Roebuck, Duncan, SC -
1012 E Shockley Ferry Rd, Anderson, SCSpace Type- Retail
For Lease- $1,500.00/MO
1 space available / 1,800 SF -
556 Perry Avenue, West Greenville, Greenville, SC -
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605 Bob Gifford Blvd, Early Branch, SCProperty Type- Industrial
For Sale- $3,700,000
Built in 1995 / Property size 50,000 SF -
110 Rainbow Lake Rd, Boiling Springs, SC -
120 S Main St, Lancaster, SCSpace Type- Office
For Lease- $5,000.00/MO
1 space available / 12,320 SF -
111 Smith Hines Rd, Woodruff Crossing, Greenville, SCSpace Type- Industrial
For Lease- $16.00/SF/YR
1 space available / 1,544 SF -
00 Whiskey Rd, Aiken, SCProperty Type- VacantLand
For Sale- Subject To Offer
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260 Columbia Ave, Chapin, SCProperty Type- Retail
For Sale- Subject To Offer
Built in 1988 / Property size 3,475 SF -
451 New Valley Rd, Summerville, SCSpace Type- Retail
For Lease- $35.00/SF/YR
4 spaces available / 1,400 - 2,800 SF -
51 Markfield Dr, Indigo Point - Harrison, Charleston, SCProperty Type- Other
For Sale- $765,000
Built in 1987 / Property size 2,155 SF -
239 & 241 Longtown Road, Killian Green, Columbia, SCProperty Type- VacantLand
For Sale- Pad A: $220,000 Pad B: $250,000
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5108 Poinsett Hwy, Sans Souci, Greenville, SC -
106 Fabrister Lane, Lexington, SCSpace Type- Industrial
For Lease- $12.00/SF/YR
2 spaces available / 1,600 SF -
945 Rice Ave Ext, Union, SC -
00 sweetwater Rd, North Augusta, SCProperty Type- VacantLand
For Sale- Call For Pricing
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2710 Gentry Memorial Highway, Pickens, SCSpace Type- Retail
For Lease- $20.00/SF/YR
1 space available / 1,200 SF -
10378 Ocean Highway, Pawleys Island, SCSpace Type- Retail
For Lease- $5,500.00/MO
1 space available / 2,500 SF -
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2214 Devine Street, Old Shandon, Columbia, SCSpace Type- Office
For Lease- $500.00 - $950.00/MO
3 spaces available / 200 - 400 SF -
303 Bleecker Street South, Bluffton, Bluffton,,, SCProperty Type- Other
For Sale- $6,300,000
Built in 2021 / Property size 10,656 SF -
5101 Augusta Rd, Lexington, SCProperty Type- Other
For Sale- $1,300,000
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111 Woodland Drive, Anderson, SCProperty Type- Multi-Family
For Sale- $334,000
Property size 4,400 SF -
TBD US 378, Conway, SCProperty Type- VacantLand
For Sale- $2,700,000