South Carolina Commercial Real Estate for Lease and Sale
Explore 3,617 listing(s) of commercial real estate in South Carolina to find the best space for your business.
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4076 Charlotte Highway, Lake Wylie, SC -
330 Scuffletown Road, Five Forks, Simpsonville, SC -
1941 Old Dunbar Road, West Columbia, SCProperty Type- Industrial
For Sale- $4,000,000
Built in 1972 / Property size 10,100 SF -
1599 Highway 101, Roebuck, Greer, SC -

What type of listing property are you looking for?
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108 E Public Sq, Laurens, SCSpace Type- Retail
For Lease- $12.00/SF/YR
1 space available / 2,200 SF -
11716 Atomic Rd, Beech Island, SCProperty Type- VacantLand
For Sale- $595,000
Built in 1965 / Property size 8,240 SF -
115 Atrium Way, Dentsville, Columbia, SC -
2324 Devine St, Old Shandon, Columbia, SC -
1620 Willingham Drive, Forest Acres, Columbia, SCSpace Type- Office
For Lease- $3,000.00/MO
1 space available / 1,039 SF -
Pelham Rd & Haywood Rd, Overbrook, Greenville, SC -
1333 Main Street, Downtown Columbia, Columbia, SCSpace Type- Office
For Lease- $21.75 - $22.50/SF/YR
2 spaces available / 2,794 - 17,594 SF -
1278 Pendleton St, West Greenville, Greenville, SC -
203 South Main Street, Mauldin, SCProperty Type- Retail
For Sale- $2,685,200
Built in 2026 / Property size 950 SF -
300 Union St, South Converse, Spartanburg, SCSpace Type- Office
For Lease- $16.50/SF/YR
1 space available / 1,587 SF -
14361 Ocean Hwy, Pawleys Island, SCSpace Type- Office
For Lease- $5,000.00/MO
1 space available / 1,500 SF -
4330 Cheyenne St, North Charleston, SCSpace Type- Industrial
For Lease- $13.50/SF/YR
1 space available / 1,420 SF -
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641 Little Tony Ave, Murrells Inlet, SCSpace Type- Office
For Lease- $650.00 - $1,600.00/MO
6 spaces available / 150 - 480 SF -
140 Spring Street, Medical University of SC, Charleston, SCProperty Type- Other
For Sale- $3,100,000
Property size 3,028 SF -
932 B Front St, Georgetown, SCSpace Type- Office
For Lease- $625.00/MO
8 spaces available / 100 - 121 SF -
754 Oak Forest Ln, Heart of Myrtle Beach, Myrtle Beach, SC -
321 E 5th North St, Summerville, SCSpace Type- Retail
For Lease- $27.00/SF/MO
1 space available / 2,654 SF -
7925 Garners Ferry Road, Southern Columbia, Columbia, SC -
1807 Cherry Road, Cedar Grove Park, Rock Hill, SCSpace Type- Retail
For Lease- $14.00 - $15.00/SF/YR
2 spaces available / 1,200 - 7,000 SF -
108 Palmetto Park Blvd, Lexington, SCSpace Type- Office
For Lease- $22.00/SF/YR
1 space available / 2,606 SF -
Montague Avenue Extension, Greenwood, SCProperty Type- VacantLand
For Sale- Subject To Offer
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294 Henry Isaac Road, Patrick, SCProperty Type- VacantLand
For Sale- $13,750
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1505 Buncombe Road, Park Place, Greenville, SCProperty Type- Industrial
For Sale- $2,500,000
Built in 1955 / Property size 38,400 SF -
496 La Mesa Street, Mount Pleasant, SC -
1339 West Martintown Road, North Augusta, SCProperty Type- VacantLand
For Sale- $450,000
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3618 Ashley Phosphate Road, North Charleston, Charleston, SCSpace Type- Office
For Lease- $1,100.00/MO
1 space available / 340 SF -
106 W Washington St, Downtown Greenville, Greenville, SC -
6842 Satchelford Road, Highland Park, Columbia, SCProperty Type- Industrial
For Sale- $499,000
Property size 4,950 SF -
2740 Navigator Circle, Sumter, SCProperty Type- VacantLand
For Sale- $75,000
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3320 Platt Springs Road, Springdale, West Columbia, SCProperty Type- Office
For Sale- $325,000
Property size 1,864 SF -
187 N Church St, Downtown Spartanburg, Spartanburg, SC -
131 State St, West Columbia, SCSpace Type- Retail
For Lease- $22.00/SF/YR
1 space available / 1,300 SF -
4225 Carolina Exchange Drive, Suite B , Carolina Forest, Myrtle Beach, SCSpace Type- Office
For Lease- $18.00/SF/YR
1 space available / 1,150 SF -
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31 Cessna Ct, Verdae, Greenville, SC -
2821 Millwood Ave, Melrose Heights, Columbia, SC -
332 Edgefield Rd, Belvedere, North Augusta, SCProperty Type- Unassigned
For Sale- $1,200,000
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125 Holiday Dr, Summerville, SC -
120 Forum Drive, Pontiac, Columbia, SC -
2650 Fassitt Road, North Charleston, SCSpace Type
- Industrial
For Lease Contact for pricing -
1980 Technology Drive, Daniel Island, Charleston, SC -
Clemson Grove-Shoppes at Pendleton Park , Anderson, Pendleton, SC -
1445 Cannon Rd, Heart of Myrtle Beach, Myrtle Beach, SCSpace Type- Industrial
For Lease- $12.75/SF/YR
1 space available / 2,200 SF -
111 Hood Rd, Welcome, Powdersville, SCProperty Type- Other
For Sale- $3,643,750
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1621 Union St, Glendale, Spartanburg, SC -
709 Mcqueen Rd, Patrick, SCProperty Type- VacantLand
For Sale- $23,750
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1415 Richland St, Downtown Columbia, Columbia, SCSpace Type- Office
For Lease- $600.00/MO
4 spaces available / 210 - 255 SF