Spartanburg County, SC Commercial Real Estate for Lease and Sale
Explore 263 listing(s) of commercial real estate in Spartanburg County, SC to find the best space for your business.
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200 Dillon Circle, Glendale, Spartanburg, SCSpace Type- Industrial
For Lease- $5.00/SF/YR
1 space available / 11,995 SF -
497 Robin Lake Road, Roebuck, Duncan, SC -
Chesnee Highway, Glendale, Spartanburg, SCSpace Type
- Industrial
For Lease Contact for pricing -
40 Tyger River Drive, Roebuck, Duncan, SC -

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5950 N Main St, Cowpens, SCProperty Type- Industrial
For Sale- Subject To Offer
Built in 1979 / Property size 333,500 SF -
1963 South Carolina 101, Roebuck, Greer, SC -
861 Double Bridge Rd, Boiling Springs, SCProperty Type- Retail
For Sale- $3,760,000
Built in 2025 / Property size 5,400 SF -
John B White Sr Blvd & Hidden Hill Road, Woodland Heights, Spartanburg, SC -
2199 Southport Road, Duncan Park, Spartanburg, SC -
185 Littlejohn St, Fairforest, Spartanburg, SC -
2187 Southport Rd, Duncan Park, Spartanburg, SCProperty Type- Retail
For Sale- $600,000
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205 West Blackstock Road, Westgate Plantation, Arcadia, SC -
521 Cedar Tree Road, Wellford, SCSpace Type- Retail
For Lease- $20.00/SF/YR
1 space available / 2,882 SF -
5965 US-221, Woodruff, Roebuck, SCProperty Type- Industrial
For Sale- $4,650,000
Property size 76,000 SF -
9091 Asheville Hwy, Wellford, Boiling Springs, SCSpace Type- Industrial
For Lease- $12.50/SF/YR
1 space available / 15,000 SF -
W Croft Cir, Croft Circle, Spartanburg, SCProperty Type- Other
For Sale- $375,000
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251 Inglesby Parkway, Duncan, SCSpace Type- Industrial
For Lease- $13.00/SF/YR
1 space available / 6,000 SF -
10243 US Hwy 29, Wellford, SCSpace Type- Industrial
For Lease- $6,500.00/MO
1 space available / 130,680 SF -
150 E Henry St, Downtown Spartanburg, Spartanburg, SCSpace Type- Office
For Lease- $24.50/SF/YR
1 space available / 16,264 SF -
1103 Ashville Hwy, Hilltop, Spartanburg, SCSpace Type- Office
For Lease Contact for pricing -
1599 Highway 101, Roebuck, Greer, SC -
160 National Avenue, Wellford, Spartanburg, SC -
1431 SC-101, Greer, SCProperty Type- Office
For Sale- $1,500,000
Built in 2001 / Property size 12,000 SF -
Kilgore Bridge Rd, Enoree, Woodruff, SCProperty Type- Other
For Sale- $18,150,000
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5502 Reidville Road, Roebuck, Moore, SCProperty Type- Office
For Sale- $370,000
Property size 1,200 SF -
470 Old Greenville Rd, Arcadia, Spartanburg, SCSpace Type- Industrial
For Lease- $12.00/SF/YR
1 space available / 11,900 SF -
110 Commercial Road, Wellford, Spartanburg, SCSpace Type- Industrial
For Lease- $6.95/SF/YR
1 space available / 17,500 SF -
2199 East Main Street, Roebuck, Duncan, SCProperty Type- VacantLand
For Sale- $1,200,000
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1802 Drayton Road | Suite 101, Drayton, Spartanburg, SCSpace Type- Office
For Lease- $26.00/SF/YR
1 space available / 8,785 SF -
12117 Highway 221, Woodruff, SCProperty Type- Office
For Sale- Subject To Offer
Property size 2,792 SF -
1723 East Main Street, Roebuck, Duncan, SCSpace Type- Retail
For Lease- $40.00 - $44.00/SF/YR
1 space available / 9,952 SF -
500 W Main St, Summerhill, Spartanburg, SCSpace Type- Retail
For Lease- $12.50 - $25.00/SF/YR
10 spaces available / 1,683 - 14,566 SF -
Plemmons Road & SC-101, Roebuck, Duncan, SC -
2116 Hwy 221, Glendale, Spartanburg, SC -
New Hope Road, Roebuck, Wellford, SCProperty Type- VacantLand
For Sale- Subject to Offer
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929 Berry Shoals Rd, Roebuck, Duncan, SC -
191 Clear Springs Ct, Greer, SCProperty Type- Industrial
For Sale- Subject To Offer
Built in 1994 / Property size 20,000 SF -
2153 E Main St, Roebuck, Duncan, SC -
149B West Main Street, Downtown Spartanburg, Spartanburg, SCSpace Type- Office
For Lease- $30.00/SF/YR
1 space available / 1,585 SF -
9855 Warren H. Abernathy Hwy, Roebuck, Spartanburg, SC -
925 Berry Shoals Rd, Roebuck, Duncan, SCSpace Type- Industrial
For Lease- $8.50/SF/YR
1 space available / 28,000 SF -
1985 South Carolina 101, Roebuck, Greer, SC -
1802 Drayton Road Suite I, Drayton, Spartanburg, SCSpace Type- Retail
For Lease- $29.00/SF/YR
1 space available / 6,979 SF -
236 Union St, Downtown Spartanburg, Spartanburg, SCProperty Type- Office
For Sale- $2,000,000
Property size 23,515 SF -
98 Southport Rd, Woodland Heights, Spartanburg, SCProperty Type- Retail
For Sale- $650,000
Built in 1998 / Property size 1,600 SF -
Fort Prince Boulevard, Wellford, Spartanburg, SCProperty Type- Other
For Sale- $1,260,000
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8211 Asheville Hwy, Southern Shops, Boiling Springs, SCSpace Type- Mixed Use
For Lease- $4,500.00/MO
1 space available / 348,480 SF -
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438 Mayfield Rd, Roebuck, Duncan, SC -
391 N Main St, Woodruff, SCProperty Type- Other
For Sale- $4,690,000
Property size 18,600 SF -
1240 Howell Road, Roebuck, Duncan, SC
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187 N Church St, Downtown Spartanburg, Spartanburg, SC -
1375 Hayne St, Saxon, Spartanburg, SC