St. Louis County, MO Office Spaces for Rent

Find the best St. Louis County, MO office space among 1,006 for rent listings currently on the market.

Hi-Pointe Business Center

7110 Oakland Avenue #200, Richmond Heights, MO
Space Type

Private Offices
For Lease

Contact for pricing
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Green Park Commerce Center II Building C

111 Rock Cliff Ct., Green Park, MO
Space Type

Office
For Lease

$7.15/SF/YR
1 space available / 5,000 SF
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751 Long Road Crossing Dr

751 Long Road Crossing Dr, Chesterfield, MO
Space Type

Office
For Lease

$21.50/SF/YR
1 space available / 30,000 SF
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7940 Watson Rd

7940 Watson Rd, Marlborough, St. Louis, MO
Space Type

Office
For Lease Contact for pricing

1 space available / 1,980 SF
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Four Seasons Shopping Center

8 Four Seasons Shopping Center, Chesterfield, MO
Space Type

Office
For Lease Contact for pricing

7 spaces available / 446 - 1,270 SF
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781 Rudder Road

781 Rudder Road, Fenton, MO
Space Type

Office
For Lease

$9.50/SF/YR
1 space available / 6,772 SF
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615-639 N New Ballas Rd

639 N New Ballas Rd, Creve Coeur, Saint Louis, MO
Space Type

Office
For Lease

$18.00/SF/YR
1 space available / 299 SF
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Physicians Office Center

10012 Kennerly Road, Sappington, St. Louis, MO
Space Type

Office
For Lease

$29.00/SF/YR
1 space available / 3,755 SF
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Mercy Hospital South - Medical Plaza

12700 Southfork Road, Suson Park, St. Louis, MO
Space Type

Office
For Lease

$28.00/SF/YR
1 space available / 4,125 SF
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760 Office Pkwy

760 Office Pkwy, Creve Coeur, MO
Space Type

Office
For Lease Contact for pricing

1 space available / 2,600 SF
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188 Weldon Parkway

188 Weldon Parkway, Maryland Heights, MO
Space Type

Office
For Lease

$12.00/SF/YR
1 space available / 2,418 SF
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Lin-Valle Center

11040 Lin Valle Dr, Green Park, Saint Louis, MO
Space Type

Office
For Lease

$12.00/SF/YR
1 space available / 1,075 SF
View Details
DePaul Medical Office Building South

12277 DePaul Drive, Bridgeton, MO
Space Type

Office
For Lease

$28.00/SF/YR
8 spaces available / 1,082 - 2,912 SF
View Details

St. Louis County, MO Office Space for Rent

Office inventory

According to our listing data, St. Louis County's office market contains 53.8M square feet of space as of 2026.

St. Louis County Office Market Breakdown by Building Size
Building Size Range	Total Square Feet
50k to 100k Sq. Ft.	12.6M Sq. Ft.
100k to 500k Sq. Ft.	27.8M Sq. Ft.
500k to 1M Sq. Ft.	2.7M Sq. Ft.
> 1M Sq. Ft.	3.3M Sq. Ft.

Data was provided by Yardi Research Data, refers to properties larger than 50,000 square feet.

Properties sized 100k to 500k Sq. Ft. make up most of the local office inventory, amounting to 27.8M square feet.

Average Rent for Office Spaces

The average rent for office space in St. Louis County is $23 per square foot. However, you can find rental rates as low as $9 per square foot here, depending on what compromises you are willing to make. If you are looking for office space priced at a certain value, you can use the filters at the top of the page to look for properties within your optimal range.

The maximum rental rate is $49 per square foot among local listings currently available for lease.

Office Spaces Classes

The office space market in St. Louis County incorporates a mix of properties of various ages, ratings, construction grades, and other quality indicators. 36.94% of total office listings in this city are in properties rated Class A. Class B accounts for 57.38% of traditional work spaces listed on the leasing market. Class C makes up 5.69% of such listings in St. Louis County. This data is current as of 2026.

St. Louis County Office Market Breakdown by Building Class
Class	Total Square Feet	Share of Total Office
A	19.9M	36.94%
B	30.8M	57.38%
C	3.1M	5.69%

Data was provided by Yardi Research Data, refers to properties larger than 50,000 square feet.

The most common factor that influences the cost of renting space for your business in any location is the property class rating. For example, St. Louis County office space rated Class A asks an average of $27.72 per square foot. Class B space in St. Louis County costs $21.42 per square foot, on average. Listings of available space in Class C buildings asked an average of $17.62 per square foot.

St. Louis County, MO Office Spaces for Rent

Hi-Pointe Business Center

Green Park Commerce Center II Building C

751 Long Road Crossing Dr

7940 Watson Rd

Four Seasons Shopping Center

781 Rudder Road

615-639 N New Ballas Rd

Physicians Office Center

Mercy Hospital South - Medical Plaza

760 Office Pkwy

188 Weldon Parkway

Lin-Valle Center

DePaul Medical Office Building South

St. Louis County, MO Office Space for Rent

Office inventory

Average Rent for Office Spaces

Office Spaces Classes

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