Manlius, NY Office Spaces for Rent

Find the best Manlius, NY office space among 25 for rent listings currently on the market.

100 E. Seneca Street

100 E. Seneca Street, Manlius, NY
Property Type

Office
For Lease

$16.00/SF/YR
1 space available / 2,500 SF
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Seven Pines Office Park

8104-8116 Cazenovia Road, Manlius, NY
Property Type

Office
For Lease Contact for pricing

1 space available / 5,000 SF
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The Market Place

4500 Pewter Ln, Manlius, NY
Property Type

Office
For Lease

$22.50/SF/YR
1 space available / 2,200 SF
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Northeast Medical Center

4000 Medical Center Drive, Manlius, Fayetteville, NY
Property Type

Office
For Lease

$23.00/SF/YR
8 spaces available / 751 - 5,011 SF
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Lyndon Office Park

7000 East Genesee Street, East Syracuse, Fayetteville, NY
Property Type

Office
For Lease Contact for pricing

4 spaces available / 475 - 1,274 SF
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6864 Genesee Street East

6864 Genesee Street East, East Syracuse, Fayetteville, NY
Property Type

Other
For Lease

$15.00/SF/YR
1 space available / 3,280 SF
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5852 Heritage Landing Drive

5852 Heritage Landing Drive, East Syracuse, NY
Property Type

Office
For Lease Contact for pricing

1 space available / 4,200 SF
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4317 E Genesee St

4317 E Genesee St, East Syracuse, Syracuse, NY
Property Type

Office
For Lease

$15.00/SF/YR
1 space available / 1,100 SF
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Widewaters Office Park - 5788 Widewaters Pkwy

5788 Widewaters Pkwy, East Syracuse, Syracuse, NY
Property Type

Office
For Lease Contact for pricing

4 spaces available / 2,650 - 11,700 SF
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Widewaters Office Park - 5784 Widewaters Pkwy

5784 Widewaters Pkwy, East Syracuse, Syracuse, NY
Property Type

Office
For Lease Contact for pricing

2 spaces available / 9,000 - 32,000 SF
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6585 Kinne Road

6585 Kinne Road , East Syracuse, Syracuse, NY
Property Type

Office
For Lease

$18.00/SF/YR
1 space available / 1,567 SF
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Frequently Asked Questions

Asking prices vary based on the property location, rating, amenities such as proximity to restaurants, cafes, and entertainment venues, as well as convenience of access to public transport, airports, and thoroughfares.
Most experts recommend an average of between 75 and 150 square feet of office space per person. However, it is important to keep in mind that how much office space you ultimately need depends on your activity and how you need to use the space, as much as it does on how many people it should accommodate. If you already know what size office would best suit your needs, use the available space size filter at the top of the search page to focus your search on the best fit for you.

You’ll find a home for almost any size of business in Manlius, as the local office market offers a wide range of options. Office spaces currently on the market go up to as much as 5,000 square feet in size for an individual listing.
You can find 2 office listing(s) for lease in Manlius, which add up to a total of 7,500 square feet. Availability on the market includes a variety of office use types, such as General Office.

The most common office use type currently available for lease in Manlius is General Office, which is offered in 1 or 50.00% of listings.
Sublease opportunities on the market include General Office.
The best choice of neighborhood for your office space will greatly depend on the elements that are most relevant to your business and your employees. However, a good criterion to start with is to look at the areas of the city that have the highest concentration of office properties, as these areas are generally well connected to transit options and have a good degree of amenity availability.
Each individual’s commuting experience will of course be different depending on a number of factors. Check the location description details for the office listings that catch your eye, to get an overview of walkability, access to public transport, the quality of infrastructure dedicated to biking commuters, as well as the proximity to parking facilities, fuel stations, and other essential amenities.
The Manlius office market incorporates a mix of properties of various ages, ratings, construction grades, and other quality indicators. Class B office space accounts for 50% of spaces listed on the leasing market.
There are, of course, a lot of things to factor in when you are looking for office space. Aspects including the accessibility of the location, the quality of the facility, the size of the space, the convenience of nearby amenities, the type and duration of the lease, and of course the cost are all part of the search and decision process. For a quick checklist of what you should take into account when researching the market, consider these seven tips for choosing the best office location for your business. Alternatively, for a comprehensive take on everything to consider when looking for office space, see our in-depth guide to finding office space for small or growing companies. The guide also includes insights from seasoned professionals and can serve as a helpful resource for growing companies, no matter their current size.
Are you looking to lease office space in the vicinity of your current location or in a particular neighborhood of Manlius? Using the interactive map, you can easily navigate to your preferred location and customize your search area around a specific point of interest. Select “Radius” from the Search Mode options menu, click on the map to set your search reference point, and expand the radius to select your desired search area. Browse available listings to find the best office space that meets your location, as well as other business needs.

Manlius, NY Office Inventory Breakdown

There are a number of factors that make a city attractive for businesses to relocate or expand, as well as for investors to enhance their portfolios through local acquisitions. Among the most important factors to consider are the size and quality of the local office market, which is an essential component of the local economy.

Total Office Space in Manlius: 36,072 Sq. Ft.

In 2025 the Manlius office market encompassed 36,072 square feet of space.

Manlius Office Market Breakdown by Building Size
Building Size Range	Total Square Feet	Share of Total Office

Manlius Office Market Breakdown by Building Quality Rating
Class	Total Square Feet	Share of Total Office
Class B	36,072 Sq. Ft.	100%

Data was provided by CommercialEdge, refers to properties larger than 50,000 square feet.

About us

CommercialCafe is your go-to commercial real estate listing source. We partner with highly respected major brokerages from across the country to ensure high-quality listings that are updated frequently. Our online marketplace lists all commercial property types from office, coworking, retail, and industrial to special purpose properties.

CommercialCafe is a trusted Yardi brand and is an integral part of the CommercialEdge network — the fastest-growing network of online real estate marketplaces, which ranks on the 1st page of Google for all top markets, attracts more than 2 million monthly visits, and generates more than 350,000 broker contacts.

Manlius, NY Office Spaces for Rent

100 E. Seneca Street

Seven Pines Office Park

The Market Place

Northeast Medical Center

Lyndon Office Park

6864 Genesee Street East

5852 Heritage Landing Drive

4317 E Genesee St

Widewaters Office Park - 5788 Widewaters Pkwy

Widewaters Office Park - 5784 Widewaters Pkwy

6585 Kinne Road

Frequently Asked Questions

Manlius, NY Office Inventory Breakdown

Total Office Space in Manlius: 36,072 Sq. Ft.

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