Pickens County, SC Office Spaces for Rent

Find the best Pickens County, SC office space among 6 for rent listings currently on the market.

Two-Story Medical Office Building in Easley’s Prime Medical Hub

201 Richard St, Easley, SC
Property

Office
Availability

1 Space

4,038 SF
Year Built

1971
For Lease Contact for pricing
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Great Restaurant/Retail Space in Downtown Liberty!

25 South Commerce Street, Liberty, SC
Property

Office

1,972 SF
Availability

1 Space

1,972 SF
Year Built

1930
For Lease Contact for pricing
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1729 Powdersville Rd

1729 Powdersville Rd, Easley, SC
Property

Office

6,000 SF
Availability

1 Space

3,000 SF
For Lease

$13.50/SF/YR
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201 E 1st Ave

201 E 1st Ave, Easley, SC
Property

Office

6,258 SF
Availability

1 Space

3,749 SF
Year Built

1987
For Lease

$20.00/SF/YR
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107 S Pendleton St

107 S Pendleton St, Easley, SC
Property

Office

8,068 SF
Availability

1 Space

156 SF
For Lease

$499.00/MO
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5208 Calhoun Memorial Hwy

5208 Calhoun Memorial Hwy, Easley, SC
Property

Office

1,220 SF
Availability

1 Space

1,220 SF
Year Built

1993
For Lease

$24.00/SF/YR
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Pickens County, SC Office Inventory Breakdown

There are a number of factors that make a city attractive for businesses to relocate or expand, as well as for investors to enhance their portfolios through local acquisitions. Among the most important factors to consider are the size and quality of the local office market, which is an essential component of the local economy.

Total Office Space in South Carolina: 185,157 Sq. Ft.

In 2025 the South Carolina office market encompassed 185,157 square feet of space.
Class A office space makes up a 26.99% share of South Carolina office inventory, while Class B office assets represent roughly 16.15% of the market total.

South Carolina Office Market Breakdown by Building Size
Building Size Range	Total Square Feet	Share of Total Office
100k to 500k Sq. Ft.	105,290 Sq. Ft.	56.87%

South Carolina Office Market Breakdown by Building Quality Rating
Class	Total Square Feet	Share of Total Office
Class A	49,968 Sq. Ft.	26.99%
Class B	29,899 Sq. Ft.	16.15%
Class C	105,290 Sq. Ft.	56.87%

Data was provided by CommercialEdge, refers to properties larger than 50,000 square feet.

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Pickens County, SC Office Spaces for Rent

Two-Story Medical Office Building in Easley’s Prime Medical Hub

Great Restaurant/Retail Space in Downtown Liberty!

1729 Powdersville Rd

201 E 1st Ave

107 S Pendleton St

5208 Calhoun Memorial Hwy

Pickens County, SC Office Inventory Breakdown

Total Office Space in South Carolina: 185,157 Sq. Ft.

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