304 Office Spaces for Rent in Saint Louis, MO

Find your best Saint Louis, MO office space among 304 for rent listings, which average an asking price of $24.6 per square foot.

Office Market FAQs

Spaces Central West End
Spaces
4625 Lindell Blvd #200 & 300, St Louis, MO
Services

Virtual Office

Open Workspace

Private Office

Dedicated Desk
Amenities

24/7 security

Access to global network

Business address

Business lounge

Cleaning services

Ergonomic furniture

Lounge area

Mail services

Money-back guarantee

Office furniture
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Bank of America Tower

100 North Broadway, Downtown Saint Louis, St. Louis, MO
Property

Office

510,202 SF
Availability

12 Spaces

230,631 SF
Year Built

1974
For Lease

$18.00/SF/YR
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1300 Hampton Avenue

1300 Hampton Avenue, Cheltenham, St Louis, MO
Property

Office

41,310 SF
Availability

2 Spaces

4,400 SF
Year Built

1950
For Lease

$20.00/SF/YR
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Fair Mercantile

5243 Shaw Avenue, The Hill, St. Louis, MO
Property

Office

59,112 SF
Availability

2 Spaces

5,706 SF
Year Built

1935
For Lease

$20.00/SF/YR
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Hadley Dean Building

1101 Lucas Avenue, Downtown Saint Louis, St. Louis, MO
Property

Office

35,000 SF
Availability

1 Space

3,000 SF
Year Built

1903
For Lease

$13.95/SF/YR
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Deloitte Building

100 South 4th Street , Downtown West Saint Louis, Saint Louis, MO
Property

Office

287,250 SF
Availability

9 Spaces

162,463 SF
Year Built

1986
For Lease

$17.75/SF/YR
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CIC St. Louis
CIC
4220 Duncan Avenue, St. Louis, MO
Services

Open Workspace

Private Office
Amenities

Bike storage

Complimentary coffee & tea

Game room

High-speed wifi

Lab space

Parking

Podcast room

Printer

Projector

Receptionist/Secretarial services
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Convention Plaza III

901 N. Tenth, Downtown Saint Louis, St. Louis, MO
Property

Office

73,000 SF
Availability

2 Spaces

44,650 SF
Year Built

1984
For Lease Contact for pricing
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Cubework St. Louis

601 East Red Bud Avenue, North Riverfront, St. Louis, MO
Property

Industrial

61,118 SF
Availability

2 Spaces

53,000 SF
Year Built

1942
For Lease Contact for pricing
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3000-3008 S Jefferson Ave

3000-3008 S Jefferson Ave, Benton Park, Saint Louis, MO
Property

Office

12,736 SF
Availability

1 Space

130 SF
Year Built

1900
For Lease

$43.85/SF/YR
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South Grand Creative Office

3030 South Grand Boulevard, Tower Grove East, St. Louis, MO
Property

Office

4,000 SF
Availability

1 Space

4,000 SF
Year Built

1905
For Lease

$15.00/SF/YR
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205 E Davis St

205 E Davis St, Patch, Saint Louis, MO
Property

Office

22,286 SF
Availability

1 Space

22,286 SF
Year Built

1962
For Lease

$9.00/SF/YR
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Monkey Building

1430 Washington Avenue, Downtown West Saint Louis, St. Louis, MO
Property

Office

27,045 SF
Availability

4 Spaces

7,719 SF
Year Built

2006
For Lease

$10.00 - $24.00/SF/YR
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1424 Washington Ave.

1424 Washington Ave Suite #300, Downtown West Saint Louis, Saint Louis, MO
Property

Office

13,500 SF
Availability

1 Space

4,300 SF
Year Built

1896
For Lease

$14.00/SF/YR
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Deloitte Building
Regus
100 South 4th Street Suite 550, St. Louis, MO
Services

Virtual Office

Open Workspace

Private Office

Dedicated Desk
Amenities

24/7 security

Access to global network

Business address

Business lounge

Cleaning services

Ergonomic furniture

Lounge area

Mail services

Money-back guarantee

Office furniture
View Details (opens in new window)
Cupples 9 at the Ballpark

900 Spruce Street, Downtown Saint Louis, St. Louis, MO
Property

Office

144,823 SF
Availability

6 Spaces

134,436 SF
Year Built

1894
For Lease Contact for pricing
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904 S 4th Street

904 S 4th Street, Downtown Saint Louis, Saint Louis, MO
Property

Office

2,252 SF
Availability

5 Spaces

2,999 SF
For Lease

$44.65 - $2,500.00/SF/YR
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717 North 16th Street

717 North 16th Street, Downtown West Saint Louis, St. Louis, MO
Property

Office

25,000 SF
Availability

2 Spaces

15,000 SF
Year Built

2001
For Lease

$12.50/SF/YR
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1210 Washington Ave

1210 Washington Avenue, Downtown West Saint Louis, St. Louis, MO
Property

Office

14,900 SF
Availability

1 Space

1,820 SF
Year Built

1925
For Lease

$12.00/SF/YR
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4565 McRee Avenue

4565 McRee Avenue, Forest Park South East, St. Louis, MO
Property

Office

47,000 SF
Availability

1 Space

20,000 SF
For Lease

$29.00/SF/YR
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1430 Olive Street

1430 Olive Street, Downtown West Saint Louis, St. Louis, MO
Property

Office

78,798 SF
Availability

1 Space

42,300 SF
Year Built

1961
For Lease

$11.95 - $13.95/SF/YR
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One Metropolitan Square

211 North Broadway, Downtown Saint Louis, St. Louis, MO
Property

Office

1,040,829 SF
Availability

13 Spaces

230,259 SF
Year Built

1989
For Lease Contact for pricing
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Cupples One Office Building

1000 Clark Avenue, Downtown Saint Louis, St. Louis, MO
Property

Office

104,666 SF
Availability

4 Spaces

27,155 SF
Year Built

1900
For Lease

$19.50/SF/YR
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The Post

900 N Tucker, Downtown Saint Louis, St. Louis, MO
Property

Office

235,000 SF
Availability

10 Spaces

149,364 SF
Year Built

1917
For Lease Contact for pricing
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Cyrus F. Blanke Building

1310 Papin Street, Downtown West Saint Louis, St. Louis, MO
Property

Office

221,000 SF
Availability

2 Spaces

23,342 SF
Year Built

1991
For Lease

$12.00/SF/YR
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5615-5619 Pershing Avenue

5615 Pershing Avenue, DeBaliviere Place, St. Louis, MO
Property

Office

27,200 SF
Availability

1 Space

4,000 SF
Year Built

1924
For Lease

$15.00/SF/YR
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Frequently Asked Questions

Asking prices vary based on the property location, rating, amenities such as proximity to restaurants, cafes, and entertainment venues, as well as convenience of access to public transport, airports, and thoroughfares.

The average rent for office space in Saint Louis is $24.6 per square foot. The minimum rental rate for office space in Saint Louis is $9 per square foot. Among listings of office space currently available for lease in Saint Louis, the maximum rental rate is $44.65 per square foot.

The most common factor that influences cost of office space in any location is the property class rating. For example, Saint Louis office space rated Class A asks an average of $25.72 per square foot. Class B office space in Saint Louis costs $22.43 per square foot, on average. Listings of office space in Class C buildings asked an average of $15.13 per square foot.

For more details on Saint Louis office space rent and sales prices, as well as overall market quality and new construction data, see Saint Louis Office Market Trends.

Most experts recommend an average of between 75 and 150 square feet of office space per person. However, it is important to keep in mind that how much office space you ultimately need depends on your activity and how you need to use the space, as much as it does on how many people it should accommodate. If you already know what size office would best suit your needs, use the available space size filter at the top of the search page to focus your search on the best fit for you.

You’ll find a home for almost any size of business in Saint Louis, as the local office market offers a wide range of options. Office spaces currently on the market go up to as much as 71,965 square feet in size for an individual listing.
However, there is a variety of differently sized opportunities below that maximum. For your consideration, the median size of an office space for lease in Saint Louis is 4,257 square feet, and the average office space size here is 9,336 square feet.

You can find 304 office listing(s) for lease in Saint Louis, which add up to a total of 2,860,090 square feet. Availability on the market includes a variety of office use types, such as General Office, Creative Office, Medical Office, Office / Retail.

The most common office use type currently available for lease in Saint Louis is General Office, which is offered in 162 or 53.29% of listings. The second-most frequent office use type listed here is Creative Office, which account for 16 or 5.26% of office space currently available.

You can search 11 office sublease listing(s) in Saint Louis, which amount to a total of 163,348 square feet. Sublease opportunities on the market include General Office, Medical Office, Office / Retail. The Saint Louis neighborhood or submarket with the most sublease listings available is Downtown Saint Louis.

The best choice of neighborhood for your office space will greatly depend on the elements that are most relevant to your business and your employees. However, a good criterion to start with is to look at the areas of the city that have the highest concentration of office properties, as these areas are generally well connected to transit options and have a good degree of amenity availability.

In Saint Louis, the greatest concentration of office space for lease opportunities is in Downtown Saint Louis, Downtown West Saint Louis, Forest Park South East.

Each individual’s commuting experience will of course be different depending on a number of factors. Check the location description details for the office listings that catch your eye, to get an overview of walkability, access to public transport, the quality of infrastructure dedicated to biking commuters, as well as the proximity to parking facilities, fuel stations, and other essential amenities.

The Saint Louis office market incorporates a mix of properties of various ages, ratings, construction grades, and other quality indicators. Roughly 44.41% of total office space listings in the city are in properties rated Class A. You will find the highest concentration of Class A office space in the Downtown Saint Louis neighborhood of Saint Louis. Class B office space accounts for 35.53% of spaces listed on the leasing market. The neighborhood with the most Class B office space is Downtown Saint Louis. Class C office space makes up 4.93% of office space available in Saint Louis.

Buildings completed in and since the year 2000 account for 4.71% of office properties in the city and incorporate a total of 87,855 square feet. About 15.29% of office space in Saint Louis is in buildings that have been renovated at least once since 2000.

Out of the office space listings currently available in Saint Louis, you can find 5 LEED-certified or LEED-proposed option(s). A total of 2 building(s) here earned a LEED-certification — certification level Silver (2).

There are, of course, a lot of things to factor in when you are looking for office space. Aspects including the accessibility of the location, the quality of the facility, the size of the space, the convenience of nearby amenities, the type and duration of the lease, and of course the cost are all part of the search and decision process. For a quick checklist of what you should take into account when researching the market, consider these seven tips for choosing the best office location for your business. Alternatively, for a comprehensive take on everything to consider when looking for office space, see our in-depth guide to finding office space for small or growing companies. The guide also includes insights from seasoned professionals and can serve as a helpful resource for growing companies, no matter their current size.

Are you looking to lease office space in the vicinity of your current location or in a particular neighborhood of Saint Louis? Using the interactive map, you can easily navigate to your preferred location and customize your search area around a specific point of interest. Select “Radius” from the Search Mode options menu, click on the map to set your search reference point, and expand the radius to select your desired search area. Browse available listings to find the best office space that meets your location, as well as other business needs.

Saint Louis, MO Office Inventory Breakdown

There are a number of factors that make a city attractive for businesses to relocate or expand, as well as for investors to enhance their portfolios through local acquisitions. Among the most important factors to consider are the size and quality of the local office market, which is an essential component of the local economy.

Total Office Space in Saint Louis: 24,391,866 Sq. Ft.

In 2024 the Saint Louis office market encompassed 24,391,866 square feet of space. Out of that total, 4,049,485 square feet were in office properties sized between 500,000 and 1,000,000 square feet. Meanwhile, 2,976,826 square feet were in office buildings sized between 50,000 and 100,000 square feet.
Class A office space makes up a 52.24% share of Saint Louis office inventory, while Class B office assets represent roughly 36.43% of the market total.

Saint Louis Office Market Breakdown by Building Size
Building Size Range	Total Square Feet	Share of Total Office
50k to 100k Sq. Ft.	2,976,826 Sq. Ft.	12.2%
100k to 500k Sq. Ft.	10,912,500 Sq. Ft.	44.74%
500k to 1M Sq. Ft.	4,049,485 Sq. Ft.	16.6%
> 1M Sq. Ft.	4,587,327 Sq. Ft.	18.81%

Saint Louis Office Market Breakdown by Building Quality Rating
Class	Total Square Feet	Share of Total Office
Class A	12,742,707 Sq. Ft.	52.24%
Class B	8,885,056 Sq. Ft.	36.43%
Class C	1,825,810 Sq. Ft.	7.49%

Data was provided by CommercialEdge, refers to properties larger than 50,000 square feet.

St. Louis, MO Office Market Overview

The St. Louis office market is robust and evolving. The city is rooted in industry and manufacturing, but healthcare and services have also grown rapidly here in the last decade. Anheuser-Busch has been a staple of the city since 1852 and it remains the North American headquarters for the beverage behemoth ABInBev. St. Louis also has several universities that have given rise to a budding biotech industry, with Washington University’s McDonnell Genome Institute being an integral part of the Human Genome Project.

304 Office Spaces for Rent in Saint Louis, MO

Spaces Central West End

Bank of America Tower

1300 Hampton Avenue

Fair Mercantile

Hadley Dean Building

Deloitte Building

CIC St. Louis

Convention Plaza III

Cubework St. Louis

3000-3008 S Jefferson Ave

South Grand Creative Office

205 E Davis St

Monkey Building

1424 Washington Ave.

Deloitte Building

Cupples 9 at the Ballpark

904 S 4th Street

717 North 16th Street

1210 Washington Ave

4565 McRee Avenue

1430 Olive Street

One Metropolitan Square

Cupples One Office Building

The Post

Cyrus F. Blanke Building

5615-5619 Pershing Avenue

Frequently Asked Questions

Saint Louis, MO Office Inventory Breakdown

Total Office Space in Saint Louis: 24,391,866 Sq. Ft.

St. Louis, MO Office Market Overview

Other Popular Searches

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304 Office Spaces for Rent in Saint Louis, MO

Frequently Asked Questions

How much does office space cost in Saint Louis, MO?

How much office space do I need?

What types of office space can I lease in Saint Louis, MO?

Can I find sublease office space in Saint Louis, MO?

Where is the best location for office space in Saint Louis, MO?

How long is the average commute to work in Saint Louis, MO?

Where can I find the highest quality office space in Saint Louis, MO?

How do I find the best office space in Saint Louis, MO?

How can I find office space for rent near me?

Saint Louis, MO Office Inventory Breakdown

Total Office Space in Saint Louis: 24,391,866 Sq. Ft.

St. Louis, MO Office Market Overview

Other Popular Searches

Popular Coworking Searches

St. Louis, MO in the news

Business Group to Move into WeWork Offices in Downtown St. Louis

About us