Rare Dental Office in Downtown Palo Alto

555 Middlefield Road, Palo Alto, CA 94301

Property Information

  • For Lease $7.50/SF/MO
  • Property Type Office - Medical Office
  • Property Size 10,752 SF
  • Lot Size 0.36 Acre
  • Building Class A
  • Year Built 1956
  • Year Renovated 2020
  • Date Updated Apr 18, 2026

Description

555 Middlefield Road is an exceptional dental opportunity in the heart of Palo Alto, one of the most affluent and supply-constrained markets in Silicon Valley. The property benefits from outstanding visibility and accessibility along Middlefield Road, with immediate proximity to Stanford University, Stanford Health Care, and Lucile Packard Children’s Hospital—providing a strong referral base and a steady flow of students, faculty, medical professionals, and nearby residents. The surrounding area is characterized by dense, high-income demographics with a well-educated population that values quality healthcare services, making it ideal for a specialty dental practice. The location is also surrounded by premier retail and lifestyle amenities along University Avenue and California Avenue, including Whole Foods, Trader Joe’s, Philz Coffee, restaurants, fitness studios, and daily-needs services that drive consistent foot traffic and patient convenience. With excellent freeway access to US-101 and strong public transportation options, 555 Middlefield Road offers a highly desirable, practice-ready location for a dentist seeking long-term growth in one of the Bay Area’s strongest markets.Well-located, professional dental office space in a modern, multi-tenant building in downtown Palo Alto. The ±1,657 SF suite is thoughtfully built out with six operatories, a dedicated lab, reception and waiting area, and ample storage, making it ideally suited for a specialty dental practice. The space is contiguous with the adjacent suite, offering the opportunity to expand to a combined total of ±2,742 square feet. The property is elevator-served with recent building upgrades and is situated near Stanford University, Stanford Health Care, and Lucile Packard Children’s Hospital, providing access to a strong referral network and affluent patient base. The location also offers excellent proximity to the retail, dining, and lifestyle amenities of University Avenue and California Avenue, including Whole Foods, Trader Joe’s, Philz Coffee, and numerous restaurants and services, enhancing convenience for both patients and staff.

Highlights

  • ±1,657 SF room for five operatories, a dedicated lab, a reception/waiting area, and ample storage/closet space
  • Fully plumbed and ready for dental use, allowing for a seamless transition and reduced upfront build-out costs
  • Ideal for a specialty dental practice such as endodontics, periodontics, orthodontics, oral surgery, or similar uses
  • Modern, elevator-served professional building with recent capital upgrades
  • Prime downtown Palo Alto location with excellent access to Stanford University, major medical facilities, and nearby retail amenities
  • Rarely available Class "A" dental office sublease opportunity in downtown Palo Alto

2 Spaces Available

204

Space Type

Medical Office

Lease Rate

$7.50/SF/MO

Total Space

1,085 SF

Floor

2nd

Divisible Space

1,085 - 2,742 SF

Available Date

Immediate

Lease Type

NNN

Sublease

Yes

Sublease Expiry

Aug 31, 2034

Can be combined with the adjacent suite for a total of 2,752 sq. ft.

206

Space Type

Medical Office

Lease Rate

$7.50/SF/MO

Total Space

1,657 SF

Floor

2nd

Divisible Space

1,657 - 2,742 SF

Available Date

Immediate

Lease Type

NNN

Sublease

Yes

Sublease Expiry

Aug 31, 2034

Can be combined with the adjacent suite for a total of 2,752 sq. ft.

Contacts

Mary Blaser

SVN | Capital West Partners

Location

Located at 555 Middlefield Road, Palo Alto, CA 94301, this property is part of the Crescent Park neighborhood and Bay Area market.

Contact Listing Broker
Mary Blaser

SVN | Capital West Partners

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.