221 Main

221 Main Street, San Francisco, CA 94105

Property Information

  • For Lease Contact for pricing
  • Property Type Office - General Office
  • Property Size 387,943 SF
  • Lot Size 1.08 Acre
  • Parking Spaces Avail. 108
  • Parking Ratio 0.28 / 1,000 SF
  • Property Tenancy Multi-Tenant
  • LEED Certified Platinum
  • Building Class A
  • Year Built 1973
  • Date Updated Apr 6, 2026

Description

221 Main is a 387,943-square-foot Class A office building with Platinum LEED certification, situated on a 1.08-acre lot in the heart of South Beach. Built with modern sustainability in mind, the property provides 108 parking spaces with a parking ratio of 0.28. Its design and features cater to businesses seeking a professional environment that aligns with eco-conscious values.

The surrounding South Beach neighborhood offers a vibrant mix of amenities and conveniences. Transportation options are abundant, with Market Street & Drumm Street and Market Street & Main Street approximately 0.3 miles away, both within walking distance. Dining options such as Sweetgreen, Prospect, and Mau are less than 0.1 miles away, while hotels like Harbor Court Hotel and Hotel Griffon are less than 0.2 miles from the property. Nearby education institutions, including Golden Gate University and the Academy of Art University, are within 0.5 miles. This dynamic location balances accessibility with a lively urban environment.

2 Spaces Available

#1650

Space Type

General Office

Lease Rate

Contact for pricing

Total Space

12,012 SF

Floor

16

Divisible Space

12,012 - 12,012 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

17 private offices

 

2 large conference rooms

 

2 medium conference rooms

 

Kitchenette/break area

 

Open Area | 25 6’ x 8’ Workstations

 

Copy Area

 

Storage Room

 

Wellness Room

 

Partically Exposed Ceilings

#400

Space Type

Creative Office

Lease Rate

Contact for pricing

Total Space

4,102 SF

Floor

4

Divisible Space

4,102 - 4,102 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

Brand New Spec Suite Underway!

 

Creative Ceilings

 

Fully Furnished

 

6 Private Offices

 

1 Large Conference Room

 

Phone Room

 

Kitchen

 

Break Area

 

Reception

Contacts

Wesley Powell

Jones Lang LaSalle

Steve Anderson

Jones Lang LaSalle

Jason Volpe

Jones Lang LaSalle

John Roskos

Jones Lang LaSalle

Lexi Castellino

Jones Lang LaSalle

Location

Located at 221 Main Street, San Francisco, CA 94105, this property is part of the South Beach neighborhood and San Francisco market.

Contact 221 Main
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