450 Mission Street

450 Mission Street, San Francisco, CA 94105

Property Information

  • For Lease Contact for pricing
  • Property Type Office - General Office
  • Property Size 76,000 SF
  • Lot Size 0.34 Acre
  • Property Tenancy Multi-Tenant
  • Building Class B
  • Year Built 1920
  • Date Updated May 20, 2026

Description

This Class B office building comprises 76,000 square feet of general office space situated on a 0.34-acre lot in San Francisco. The property offers a substantial footprint suitable for tenants seeking significant office capacity in an established structure. The building is situated in Yerba Buena, a neighborhood known for its cultural institutions and urban parks. The nearby Yerba Buena Gardens, approximately 0.2 miles away, provides green space and public gathering areas. The neighborhood benefits from proximity to the Museum of Modern Art and the Contemporary Jewish Museum, drawing foot traffic and activity to the area. Public transportation options are accessible within the neighborhood, connecting tenants to broader San Francisco destinations.

5 Spaces Available

450 Mission Street #204

Space Type

Creative Office

Lease Rate

Contact for pricing

Total Space

3,483 SF

Floor

2

Divisible Space

3,483 - 3,483 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

Available now. 2 Conference Rooms, 1 Private Office, Kitchen, Open space for 30+ Workstations, Excellent Natural Light, Operable Windows. 

450 Mission Street #300

Space Type

Creative Office

Lease Rate

Contact for pricing

Total Space

15,911 SF

Floor

3

Divisible Space

15,911 - 15,911 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

 

450 Mission Street #400

Space Type

Creative Office

Lease Rate

Contact for pricing

Total Space

13,416 SF

Floor

4

Divisible Space

13,416 - 13,416 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

Available now. 1 Large Conference Rooms, 6 Private Offices/Meeting Rooms, Kitchen with Break Area, High 13 Foot Ceilings, Open Space for ±75 Workstations, Operable Windows, Excellent Natural Light. 

450 Mission Street #500

Space Type

Creative Office

Lease Rate

Contact for pricing

Total Space

10,152 SF

Floor

5

Divisible Space

10,152 - 10,152 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

Available now 4 conference rooms 4 private offices / meeting rooms Open space for ±45 workstations Server room 2 storage rooms Copy room Kitchen with break area High 13 foot ceilings Operable window Excellent natural light 

450 Mission Street #501

Space Type

Creative Office

Lease Rate

Contact for pricing

Total Space

5,782 SF

Floor

5

Divisible Space

5,782 - 5,782 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

AVAILABLE NOW. 2 LARGE CONFERENCE ROOMS 3 PRIVATE OFFICES/MEETING ROOMS OPEN SPACE FOR ±32 DESKS KITCHEN WITH BREAK AREA HIGH 13 FOOT CEILINGS OPERABLE WINDOWS EXCELLENT NATURAL LIGHT. 

Contacts

Location

Located at 450 Mission Street, San Francisco, CA 94105, this property is part of the Yerba Buena neighborhood and San Francisco market.

Contact 450 Mission Street
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