642 Harrison Street

642 Harrison Street, San Francisco, CA 94107

Property Information

  • For Lease Contact for pricing
  • Property Type Office - General Office
  • Property Size 50,580 SF
  • Lot Size 0.31 Acre
  • Property Tenancy Multi-Tenant
  • Building Class B
  • Year Built 1925
  • Date Updated May 27, 2026

Description

642 Harrison Street is a 50,580-square-foot office building situated on a 0.31-acre lot in the Yerba Buena neighborhood of San Francisco. Classified as a Building Class B property, this office space provides a functional option for tenants seeking workspace in a dynamic urban setting. Originally built in 1925, the property is ideal for businesses looking to establish themselves in a vibrant, well-connected location.

The surrounding Yerba Buena area offers a wide array of amenities and transportation options. Restaurants such as Pazzia and Boochmania are within approximately 0.1 miles, offering convenient dining choices, while hotels like The Clancy, Autograph Collection and W San Francisco are within walking distance. Transportation is easily accessible, with the Moscone Center Garage only 0.17 miles away and multiple taxi stands located within 0.5 miles. Additionally, cultural and educational institutions, including the Academy of Art University, are nearby, making the location appealing for creative and academic professionals.

1 Space Available

#100/101

Space Type

General Office

Lease Rate

Contact for pricing

Total Space

11,130 SF

Divisible Space

11,130 - 11,130 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

• Available September 2025\n• Furniture included\n• 12 enclosures of various sizes\n• ~50 workstations\n• Exclusive game room /\nlounge

Contacts

Location

Located at 642 Harrison Street, San Francisco, CA 94107, this property is part of the Yerba Buena neighborhood and San Francisco market.

Contact 642 Harrison Street
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