Genesis 4000 Shoreline

4000 Shoreline Court, South San Francisco, CA 94080

Property Information

  • For Lease Contact for pricing
  • Property Type Office - Life Sciences
  • Property Size 72,000 SF
  • Lot Size 2.41 Acre
  • Parking Spaces Avail. 252
  • Parking Ratio 3.50 / 1,000 SF
  • Property Tenancy Vacant
  • Building Class B
  • Year Built 2002
  • Date Updated Jun 22, 2026

Description

Genesis 4000 Shoreline is a 72,000-square-foot Class B office building set on a 2.41-acre lot with convenient on-site parking totaling 252 spaces at a 3.5 parking ratio. Built in 2002, the property combines functionality and accessibility, offering ample space for businesses seeking a professional setting in South San Francisco. Its thoughtful design accommodates tenant needs while providing practical parking solutions for staff and visitors alike.

Situated in South San Francisco, the property benefits from proximity to a variety of amenities. Hotels such as Homewood Suites and DoubleTree by Hilton are just minutes away, providing convenient accommodations for visitors. Dining options, including Brisbane Lunch Truck and Subway, are within 1.5 miles, while Blink charging stations are approximately 0.5 miles away for electric vehicle users. The neighborhood also offers easy access to education facilities like Brisbane Elementary School and childcare centers such as Silverspot Co-operative Nursery School, making it an advantageous location for professionals balancing work and life.

3 Spaces Available

2nd Floor

Space Type

Life Sciences

Lease Rate

Contact for pricing

Total Space

24,581 SF

Floor

2

Divisible Space

12,500 - 24,581 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

Lab Area Includes: • Biology labs & support rooms • House gases: • CDA, Vac & Co2 • Tissue culture • Vivarium • (3) Fume hoods

 

3rd Floor

Space Type

Life Sciences

Lease Rate

Contact for pricing

Total Space

24,357 SF

Floor

3

Divisible Space

24,357 - 24,357 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

Office Area Includes: • (1) Conference room • (1) Training room • (15) Private offices • Open office area • IT room • Showers

Lab Area Includes: • Biology lab & support rooms • Chemistry lab • Cold room • House gases: • CDA, Vac & Co2 • Tissue culture room • Vivarium • (6) Fume hoods 

4th Floor

Space Type

Life Sciences

Lease Rate

Contact for pricing

Total Space

24,357 SF

Floor

4

Divisible Space

24,357 - 24,357 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

Lab Area Includes: • Biology labs & support rooms • House gases: • CDA, Vac & Co2 • (5) Fume hoods

Office Area Includes: • (4) Conference rooms • (20) Private offices • Open office area • IT room 

Contacts

Location

Contact Genesis 4000 Shoreline
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.