Genesis 4000 Shoreline

4000 Shoreline Court, South San Francisco, CA 94080

Property Information

  • For Lease Contact for pricing
  • Property Type Office - Life Sciences
  • Property Size 72,000 SF
  • Lot Size 2.41 Acre
  • Parking Spaces Avail. 252
  • Parking Ratio 3.50 / 1,000 SF
  • Property Tenancy Multi-Tenant
  • Building Class B
  • Year Built 2002
  • Date Updated Apr 14, 2026

Description

Genesis 4000 Shoreline is a 72,000-square-foot Class B office building set on a 2.41-acre lot with convenient on-site parking totaling 252 spaces at a 3.5 parking ratio. Built in 2002, the property combines functionality and accessibility, offering ample space for businesses seeking a professional setting in South San Francisco. Its thoughtful design accommodates tenant needs while providing practical parking solutions for staff and visitors alike.

Situated in South San Francisco, the property benefits from proximity to a variety of amenities. Hotels such as Homewood Suites and DoubleTree by Hilton are just minutes away, providing convenient accommodations for visitors. Dining options, including Brisbane Lunch Truck and Subway, are within 1.5 miles, while Blink charging stations are approximately 0.5 miles away for electric vehicle users. The neighborhood also offers easy access to education facilities like Brisbane Elementary School and childcare centers such as Silverspot Co-operative Nursery School, making it an advantageous location for professionals balancing work and life.

1 Space Available

2nd Floor

Space Type

Life Sciences

Lease Rate

Contact for pricing

Total Space

24,581 SF

Floor

2

Divisible Space

24,581 - 24,581 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

High-end lab build-outs • Biology labs & lab support • CDA, vacuum, Co2 & DI water • Tissue culture • Vivarium • (3) Three 6’ fume hoods • Emergency generator • 55% office, 45% lab Built for laboratory research and dedicated to best-in-class biotechnology. Prime location within South San Francisco segment of Sierra Point. Every suite is equipped with flexible lab environment systems and firstclass lab equipment. Full-floor tenant identity. 

Contacts

Rebekah Studer

Phase 3 Real Estate Partners

Timo Provosty

CBRE

Dino Perazzo

CBRE

Location

Contact Genesis 4000 Shoreline
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