Lee County, FL Commercial Real Estate for Lease and Sale
Explore 773 listing(s) of commercial real estate in Lee County, FL to find the best space for your business.
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5661 Independence Cir, Villas, Fort Myers, FLSpace Type- Industrial
For Lease- $17.50 - $22.00/SF/YR
1 space available / 5,800 SF -
3607 & 3613 Colonial Ct, Forum, FORT MYERS, FLProperty Type- VacantLand
For Sale- $2,500,000
Property size 3.5 Acre -
13232 Palm Beach Blvd, Fort Myers, FL -
11270 State Road 82, Olympia - Sherwood, Fort Myers, FL -

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1939-1941 Park Meadows Drive Fort Myers, Villas, Fort Myers, FL -
10041 University Plaza Dr, Miromar Lakes, Fort Myers, FL -
17651 San Carlos Blvd, Palm Isles, Fort Myers Beach, FL -
3621 Cleveland Ave, Winkler, Fort Myers, FL -
27801 Old 41rd, Bonita Springs, FLProperty Type- Retail
For Sale- $3,999,000
Built in 2003 / Property size 5,833 SF -
26831 South Tamiami Trail, Bonita Springs, FLSpace Type- Retail
For Lease- $31.00/SF/YR
1 space available / 975 SF -
6351 Bayshore Road, North Fort Myers, FL -
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2350 Champion Ring Rd, Forum, Fort Myers, FL -
16101 Lee Road, Fiddlesticks, Fort Myers, FLProperty Type- Industrial
For Sale- $613,050
Built in 2024 / Property size 34,170 SF -
17960 N. Tamiami Trail, North Fort Myers, FLSpace Type- Land
For Lease- $90,000.00 - $100,000.00/YR
2 spaces available / 42,688.8 - 68,389.2 SF -
5261 Pine Island Rd NW, St. James City, Bokeelia, FLProperty Type- Retail
For Sale- $1,600,000
Built in 1979 / Property size 4,704 SF -
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5546 LEE BLVD, Lehigh Acres, FL -
5546 LEE BLVD, Lehigh Acres, FL -
16500 Oriole Road, Fiddlesticks, Fort Myers, FL -
2945 Estero Blvd, Fort Myers Beach, FLProperty Type- VacantLand
For Sale- $12,000,000/SF
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9180 Forum Corporate Pkwy, Forum, Fort Myers, FL -
231 Del Prado Blvd S, Hancock, Cape Coral, FL -
931 & 939 NE 7th Street, Diplomat, Cape Coral, FLProperty Type- Industrial
For Sale- $750,000
Built in 1985 / Property size 2,250 SF -
5441 Lee St, Lehigh Acres, FLSpace Type- Industrial
For Lease- $2,000.00 - $3,700.00/MO
2 spaces available / 1,155 - 2,310 SF -
18731 Three Oaks Pkwy, Three Oaks, Fort Myers, FLProperty Type- Retail
For Sale- $200 PSF
Property size 31,749 SF -
2617 Forum Blvd, Forum, Fort Myers, FL -
1507 Del Prado Blvd, Hancock, Cape Coral, FL -
21750 Via Coconut Point, Estero Town Center, Estero, FL -
1122 Northeast 7th Terrace, Diplomat, Cape Coral, FLProperty Type- VacantLand
For Sale- $1,699,000
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2481 Del Prado Boulevard North, Diplomat, Cape Coral, FL -
3401 Bonita Beach Road, Bonita Springs, FLSpace Type- Retail, Office
For Lease- $15.00/SF/YR
2 spaces available / 861 - 1,728 SF -
3614 5th St W, Lehigh Acres, FL -
1211 Seaboard St, Dunbar, Fort Myers, FL -
9510 Thunder Rd, Southwest Florida Airport, Fort Myers, FLProperty Type- Other
For Sale- $3,475,000
Property size 4.14 Acre -
1626 Medical Ln, Palm Lee, Fort Myers, FLSpace Type- Office
For Lease- $15.00 - $20.00/SF/YR
1 space available / 27,264 SF -
11485 S Cleveland Ave, Page Park, Fort Myers, FL -
8771 College Pkwy, Cypress Lake, Fort Myers, FL -
6120 Winkler Rd, Cypress Lake, Fort Myers, FLProperty Type- Office
For Sale- $546,700
Built in 1986 / Property size 2,200 SF -
6080 Jonathans Bay Dr, Estero Bay Park, Fort Myers, FL -
1015-1070 Hancock Creek S. Blvd., Hancock, Cape Coral, FLProperty Type- VacantLand
For Sale- $2,800,000
Property size 6.54 Acre -
0 Country Lakes Dr, Buckingham, Fort Myers, FLProperty Type- VacantLand
For Sale- $3,395,000
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2451 SW Pine Island Road, Burnt Store, Cape Coral, FL -
1715 Cape Coral Parkway West, Pelican, Cape Coral, FLSpace Type- Office
For Lease- $22.00/SF/YR
1 space available / 1,284 SF -
9390 Dynasty Drive, Forum, Fort Myers, FL -
13379 McGregor Blvd., Cypress Lake, Fort Myers, FLSpace Type- Office
For Lease- $16.00/SF/YR
1 space available / 2,400 SF -
12800-12871 University Drive Fort Myers, Villas, Fort Myers, FL -
13811 Metropolis Avenue, Villas, Fort Myers, FLSpace Type- Office
For Lease- $29.50/SF/YR
1 space available / 9,581 SF -
6700 Bayshore Road, North Fort Myers, FL -
2140 Flint Drive, Eastwood Village, Fort Myers, FLSpace Type- Land
For Lease- $5,500.00/MO
1 space available / 74,923.2 SF -
4600 Summerlin Road, Palm Lee, Fort Myers, FL -
3960 Canal St, Eastwood Village, Fort Myers, FLProperty Type- VacantLand
For Sale- $1,495,000
Property size 8.17 Acre -
275 SW 4th St, Trafalgar, Cape Coral, FLProperty Type- Multi-Family
For Sale- $1,800,000
Built in 2023 / Property size 7,020 SF