Port St. Lucie, FL Commercial Real Estate for Lease and Sale
Explore 100 listing(s) of commercial real estate in Port St. Lucie, FL to find the best space for your business.
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1801 Southeast Hillmoor Drive-Unit A-107, Downtown Port St. Lucie, Port St. Lucie, FLSpace Type- Office
For Lease- $28.00/SF/YR
1 space available / 1,530 SF -
1380 Southwest Import Drive, Gatlin Commons, Port St. Lucie, FL -
870-910 St Lucie W Blvd, Lake Forest Pointe, Port St. Lucie, FLSpace Type
- Retail
For Lease- $45.00/SF/YR
1 space available / 2,496 SF -
NWC of Becker Rd & SW Village Pkwy, Southern Grove, Port St Lucie, FL -

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US-1 & Saegar Avenue, Lake Charles, Port St Lucie, FL -
3001 SW Port St Lucie Blvd, Parks Edge, Port St. Lucie, FLProperty Type- Retail
For Sale- $4,580,000
Built in 2018 / Property size 7,250 SF -
585 NW Lake Whitney Place, St. Lucie West, Port St. Lucie, FLSpace Type- Office
For Lease- $25.00/SF/YR
1 space available / 6,619 SF -
1880 SW Fountainview Blvd., The Belmont at St Lucie West, Port St. Lucie, FL -
202-204 SW Port Street Lucie Blvd, Thornhill, Port St. Lucie, FL -
7528 US-1, Spanish Lakes, Port St. Lucie, FLSpace Type- Retail
For Lease- $21.00/SF/YR
4 spaces available / 1,283 - 1,750 SF -
501 Southwest Port Saint Lucie Boulevard, Oak Hammock, Port St. Lucie, FLSpace Type- Office
For Lease- $24.00/SF/YR
1 space available / 1,000 SF -
SW Becker Rd & SW Village Pkwy, Southern Grove, Port St. Lucie, FL -
2120-2130 SW Gatlin Blvd, Newport Isle, Port St. Lucie, FL -
St Lucie West, St. Lucie West, Port St. Lucie, FL -
905 E Prima Vista Blvd, River Park, Port St. Lucie, FL -
648 Southwest Port Saint Lucie Boulevard, Port St. Lucie, FL -
2120-2130 SW Gatlin Blvd, Newport Isle, Port St. Lucie, FL -
605 NW Prima Vista Blvd, River Park, Port St. Lucie, FL -
Hegener Dr, Southern Grove, Port St. Lucie, FL -
1631 SW Gatlin Blvd, Oak Hammock, Port St. Lucie, FLSpace Type- Office
For Lease- $25.00/SF/YR
1 space available / 1,288 SF -
200 SW Peacock Blvd Port St, Lake Charles, Port St. Lucie, FL -
9100-9198 US Highway 1, Port St. Lucie Industrial Park, Port St. Lucie, FL -
6940 Heritage Dr, Oleander Pines, Port Saint Lucie, FLProperty Type- Industrial
For Sale- $650,000
Built in 2002 / Property size 3,213 SF -
2250 SW Gatlin Blvd, Portofino Isles, Port Saint Lucie, FL -
10512-10914 Southwest Village Pkwy, Tradition, Port St. Lucie, FL -
11530 SW Village Pkwy, Southern Grove, Port St. Lucie, FL -
567 NW Lake Whitney Place, St. Lucie West, Port St. Lucie, FL -
SW Becker Rd & SW Village Pkwy, Southern Grove, Port St. Lucie, FL -
10753 S US Highway 1, Sandpiper Bay, Port Saint Lucie, FL -
826 NE Camino St, River Park, Port St. Lucie, FL -
7528 US-1, Spanish Lakes, Port St. Lucie, FL -
NW Lake Whitney Place, St. Lucie West, Port St. Lucie, FL -
2155 Settle Avenue, Reserve Commerce Park, Port St. Lucie, FLSpace Type- Industrial
For Lease- $16.00/SF/YR
2 spaces available / 1,700 SF -
12050 SW Tom Mackie Blvd, Southern Grove, Port St. Lucie, FLSpace Type- Industrial
For Lease- $11.00 - $20.00/SF/YR
8 spaces available / 6,017 - 127,634 SF -
3201 SW PORT ST LUCIE, Villas of Windmill Point, Port St. Lucie, FL -
3203 SW Port St. Lucie Boulevard, Gatlin, Port St. Lucie, FLSpace Type- Retail
For Lease- $22.00/SF/YR
3 spaces available / 900 - 1,256 SF -
Tilton Road, Spanish Lakes, Port St. Lucie, FL -
1125 SE Port St. Lucie Blvd, Morningside, Port St. Lucie, FLSpace Type- Retail
For Lease- $20.00 - $27.08/SF/YR
2 spaces available / 1,000 - 2,400 SF -
NW Lake Whitney Place, St. Lucie West, Port St. Lucie, FLProperty Type- Office
For Sale- Call Agent for OM
Built in 2015 / Property size 165,722 SF -
3453 SW Darwin Blvd, Sawgrass Lakes, Port Saint Lucie, FLProperty Type- Other
For Sale- $125,000
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10753 S US Highway 1, Sandpiper Bay, Port Saint Lucie, FL -
2250 SW Gatlin Boulevard, Newport Isle, Port St. Lucie, FL -
247-295 Port St. Lucie Boulevard, Thornhill, Port St. Lucie, FL -
1333 St Lucie W Blvd, St. Lucie West, Port St. Lucie, FL -
1290 SE Port St Lucie Blvd, Sandpiper Bay, Port Saint Lucie, FL -
375 SW Becker Rd, Paar, Port Saint Lucie, FLProperty Type- VacantLand
For Sale- Subject To Offer
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1880 SW Fountainview Blvd., The Belmont at St Lucie West, Port St. Lucie, FL