Port St. Lucie, FL Commercial Real Estate for Lease and Sale
Explore 97 listing(s) of commercial real estate in Port St. Lucie, FL to find the best space for your business.
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2100 SE Hillmoor Drive Unit 204A, Eastlake Village, Port St. Lucie, FLSpace Type- Office
For Lease- $29.20/SF/YR
1 space available / 940 SF -
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1857 SE Port St Lucie Blvd, Morningside, Port St. Lucie, FLSpace Type- Office
For Lease- $18.50/SF/YR
1 space available / 1,058 SF -
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7121 S US Highway 1, River Park, Port Saint Lucie, FLSpace Type- Retail
For Lease- $12.00 - $17.00/SF/YR
4 spaces available / 6,480 - 21,126 SF -
751 NW Airoso Blvd, River Park, Port Saint Lucie, FL -
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2095 NW Commerce Lakes Dr, Reserve Commerce Park, Port Saint Lucie, FLProperty Type- Industrial
For Sale- $6,400,000
Built in 2026 / Property size 23,654 SF -
870 St. Lucie W Blvd, Lake Forest Pointe, Port St. Lucie, FL -
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2400 Southeast Leithgow Street, Eastport St. Lucie, Port St. Lucie, FL -
247-295 Port St. Lucie Boulevard, Thornhill, Port St. Lucie, FL -
7528 US-1, Spanish Lakes, Port St. Lucie, FLSpace Type
- Retail
For Lease- $21.00/SF/YR
4 spaces available / 1,283 - 1,750 SF -
2250 SW Gatlin Boulevard, Newport Isle, Port St. Lucie, FL
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Tilton Road, Spanish Lakes, Port St. Lucie, FL
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648 Southwest Port Saint Lucie Boulevard, Port St. Lucie, FL
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565 NW Prima Vista Blvd, River Park, Port St. Lucie, FLProperty Type
- Retail
For Sale- $2,652,000
Built in 2025 / Property size 1,730 SF -
7630 S Us Highway 1, Spanish Lakes, Port Saint Lucie, FLSpace Type
- Retail
For Lease- $23.00/SF/YR
2 spaces available / 928 - 1,849 SF -
10753 S US Highway 1, Sandpiper Bay, Port Saint Lucie, FL
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3001 SW Port St Lucie Blvd, Parks Edge, Port St. Lucie, FLProperty Type
- Retail
For Sale- $4,580,000
Built in 2018 / Property size 7,250 SF -
11530 SW Village Pkwy, Southern Grove, Port St. Lucie, FL
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9100-9198 US Highway 1, Port St. Lucie Industrial Park, Port St. Lucie, FL
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7528 US-1, Spanish Lakes, Port St. Lucie, FL
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905 E Prima Vista Blvd, River Park, Port St. Lucie, FL
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St Lucie West, St. Lucie West, Port St. Lucie, FL
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605 NW Prima Vista Blvd, River Park, Port St. Lucie, FL
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SW Becker Rd & SW Anthony F. Sansone Sr. Blvd, Southern Grove, Port St. Lucie, FL
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US-1 & Saegar Avenue, Lake Charles, Port St Lucie, FL
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3201 SW PORT ST LUCIE, Villas of Windmill Point, Port St. Lucie, FL
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12051 SW Tom Mackie Blvd, Southern Grove, Port Saint Lucie, FL
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1631 SW Gatlin Blvd, Oak Hammock, Port St. Lucie, FLSpace Type
- Office
For Lease- $25.00/SF/YR
1 space available / 1,288 SF -
1880 SW Fountainview Blvd., The Belmont at St Lucie West, Port St. Lucie, FL
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10753 S US Highway 1, Sandpiper Bay, Port Saint Lucie, FL
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826 NE Camino St, River Park, Port St. Lucie, FL
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1125 SE Port St. Lucie Blvd, Morningside, Port St. Lucie, FLSpace Type
- Retail
For Lease- $20.00 - $27.08/SF/YR
2 spaces available / 1,000 - 2,400 SF -
SW Becker Rd & SW Village Pkwy, Southern Grove, Port St. Lucie, FL
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2155 Settle Avenue, Reserve Commerce Park, Port Saint Lucie, FLSpace Type
- Industrial
For Lease- $17.00 - $18.00/SF/YR
2 spaces available / 850 - 1,700 SF -
3203 SW Port St. Lucie Boulevard, Gatlin, Port St. Lucie, FLSpace Type
- Retail
For Lease- $22.00/SF/YR
3 spaces available / 900 - 1,256 SF -
1333 St Lucie W Blvd, St. Lucie West, Port St. Lucie, FL
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10570 South Federal Highway, Port St. Lucie, FLSpace Type
- Private Offices
For Lease-
From $545/month
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202-204 SW Port Street Lucie Blvd, Thornhill, Port St. Lucie, FL
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1290 SE Port St Lucie Blvd, Sandpiper Bay, Port Saint Lucie, FL
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2250 SW Gatlin Blvd, Portofino Isles, Port Saint Lucie, FL
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Becker Rd & I-95 Port St Lucie, Tesoro, Port St. Lucie, FL
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200 NW PEACOCK BLVD, St. Lucie West, Port St. Lucie, FL
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12050 SW Tom Mackie Blvd, Southern Grove, Port St. Lucie, FLSpace Type
- Industrial
For Lease- $11.00 - $20.00/SF/YR
7 spaces available / 6,017 - 127,634 SF -
1860 Southwest Fountainview Boulevard #100, Port St. Lucie, FLSpace Type
- Private Offices
For Lease-
From $625/month
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1880 SW Fountainview Blvd., The Belmont at St Lucie West, Port St. Lucie, FLProperty Type
- VacantLand
For Sale- $1,600,000
Property size 1.42 Acre