Syracuse, NY Commercial Real Estate for Lease and Sale

Explore 171 listing(s) of commercial real estate in Syracuse, NY to find the best space for your business.

Lockwood-JKS Roofing-Subway-HTG

2043 Erie Blvd E, Salt Springs, Syracuse, NY
Property Type

Retail
For Sale

$1,750,000
Built in 2009 / Property size 9,049 SF
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2500 Burnet Ave

2500 Burnet Ave, Eastwood, Syracuse, NY
Property Type

Retail
For Sale

$299,000
Property size 816 SF
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1320-1326 Genesee St W

1320-1326 Genesee St W, Westside Syracuse, Syracuse, NY
Property Type

Retail
For Sale

$320,000/SF
Built in 1955 / Property size 7,774 SF
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1443 West Genesee Street

1443 West Genesee Street, Far Westside Syracuse, Syracuse, NY
Space Type

Retail
For Lease Contact for pricing

1 space available / 3,300 SF
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351 South Warren Street

351 South Warren Street, Syracuse, NY
Space Type

Private Offices
For Lease

From $500/month
Space for 1 to 50 people
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White Memorial Building

100 East Washington Street, Downtown Syracuse, Syracuse, NY
Space Type

Retail
For Lease Contact for pricing

1 space available / 1,371 SF
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716 James St

716 James St, Near Northeast Syracuse, Syracuse, NY
Space Type

Office
For Lease Contact for pricing

3 spaces available / 1,070 - 4,202 SF
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South Crouse Commons

315 South Crouse Avenue, Near Eastside Syracuse, Syracuse, NY
Space Type

Office
For Lease Contact for pricing

1 space available / 6,880 SF
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1203 Geddes St S

1203 Geddes St S, Near Westside Syracuse, Syracuse, NY
Property Type

Retail
For Sale

$175,000
Built in 1940 / Property size 2,200 SF
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Rockwest Center

1005 West Fayette Street, Near Westside Syracuse, Syracuse, NY
Space Type

Office
For Lease

$8.00/SF/YR
1 space available / 35,000 SF
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406 Kirkpatrick St

406 Kirkpatrick St, Washington Square, Syracuse, NY
Property Type

Retail
For Sale

$430,000
Property size 4,800 SF
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320 West Taylor Street

320 West Taylor Street, Southwest Syracuse, Syracuse, NY
Property Type

Industrial
For Sale

$1,900,000
Property size 51,148 SF
View Details

Frequently Asked Questions

Here is a rundown of the primary commercial real estate property types currently available in Syracuse:
- Office Space: The market includes 3,572,695 square feet of office spaces in addition to 96 coworking locations.
- Retail Space: Between malls, restaurants and stores, Syracuse is home to 693,543 square feet of available retail space.
- Industrial Space: Warehouses, distribution centers, manufacturing facilities and other industrial types total 628,513 square feet of available space in Syracuse.
The average rent for commercial real estate in Syracuse is $17.08 per square foot. However, specific rates may vary widely by property type, class and quality. The cheapest commercial space in Syracuse costs $5, while the city’s premium locations ask up to $30.
Here is a breakdown of the average size of different property classes (also known as asset class or property type):
- Class A/A+ properties have an average size of 185,879 square feet.
- Class B properties are sized 54,716 square feet, on average.
- Class C properties span an average of 16,488 square feet.
The best area for commercial real estate in Syracuse will depend greatly on your needs. The neighborhood with the largest overall number of commercial listings is Downtown Syracuse, home to no fewer than 63 listings for space of all types. If you're looking for office space, Downtown Syracuse has the highest concentration of office listings at 48.

Meanwhile, Southwest Syracuse has the highest number of industrial availabilities (3), while Downtown Syracuse boasts the largest number of retail listings in the city (12).
CommercialCafe’s CRE offering in Syracuse is enabled by a network of 86 active brokers from 35 different firms, ensuring a wide variety of listings. Working with an experienced professional can make a real difference. Learn more about the benefits of working with a broker.

To get in touch with a broker, use the "Contact Property" button on this search page or fill in the contact form provided on each individual property’s listing page.
The profitability of a commercial real estate investment depends on a multitude of factors working together. These factors include the quality of the asset itself, local market conditions, the state of the local economy and the demand for that particular type of commercial property, to name a few.

Asking rents in the city can be as high as $30 per square foot. In particular, the property type commanding the highest lease rates in Syracuse is Office space.
The average size of a commercial property here stands at 483,891. However, different asset classes and zoning laws will result in vastly different property sizes. Here is a breakdown of the average size of different commercial asset classes in Syracuse:
Office properties:
- Average size: 48,942 square feet.
- Largest property: Space Available (180,000 square feet).
Retail properties:
- Average size: 17,784 square feet.
- Largest property: Full Building (8,320 square feet).
Industrial properties:
- Average size: 28,569 square feet.
- Largest property: 123 Larned St (34,849 square feet).

Syracuse, NY Commercial Space Listings

Commercial Space for Lease - Breakdown

The 105 listings for commercial real estate currently available for rent in Syracuse add up to 1,538,920 square feet across various property types. Here's a breakdown of the available space by category:

Property Type	Count of Listings	Total Sq. Ft.
Office	61	861,957
Retail	26	78,121
Industrial	12	114,952
Other	6	483,890

Office properties:

The market has 61 active office listings, encompassing 861,957 square feet.
Syracuse office spaces currently listed on CommercialCafe represent 58% of the total commercial real estate market in Syracuse, compared to an average of 39% across all markets tracked by CommercialCafe.

Retail Space:

There are 26 retail listings available, adding up to a total of 78,121 square feet.
Retail spaces account for approximately 24% of the local commercial market, while the average share taken up by retail in all U.S. markets is 34%.

Industrial Space:

The industrial market in Syracuse offers 12 listings, amounting to 114,952 available square feet.
Industrial spaces, including warehouses and manufacturing sites, make up about 11% of the total commercial space available in the market, compared to a nationwide average of 25%.

The data presented in this section was last updated as of October 07, 2026

Commercial Space for Sale - Breakdown

There are currently 67 properties listed for sale in the Syracuse market, adding up to 1,385,151 square feet of space available for purchase. Here is a breakdown of the commercial space for sale listed locally:

14 office properties
19 retail properties
11 industrial properties

The data presented in this section was last updated as of October 07, 2026

Property Type	Count of Listings	Total Sq. Ft.
Office	14	507,857
Retail	19	198,080
Industrial	11	429,738
Other	23	249,476

Syracuse, NY Commercial Real Estate for Lease and Sale

Lockwood-JKS Roofing-Subway-HTG

2500 Burnet Ave

1320-1326 Genesee St W

1443 West Genesee Street

351 South Warren Street

White Memorial Building

716 James St

South Crouse Commons

1203 Geddes St S

Rockwest Center

406 Kirkpatrick St

320 West Taylor Street

Frequently Asked Questions

Syracuse, NY Commercial Space Listings

Commercial Space for Lease - Breakdown

Commercial Space for Sale - Breakdown

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