Syracuse, NY Commercial Real Estate for Lease and Sale

Explore 166 listing(s) of commercial real estate in Syracuse, NY to find the best space for your business.

CRE Market FAQs

2407 Valley Drive

2407 Valley Drive, South Valley, Syracuse, NY
Property Type

VacantLand
For Sale

$125,000
Property size 4 Acre
View Details
1001 Genesee St W N

1001 Genesee St W N, Westside Syracuse, Syracuse, NY
Space Type

Retail
For Lease

$20.00/SF/YR
2 spaces available / 978 - 1,700 SF
View Details
1401 Erie Blvd East

1401 Erie Blvd East, Near Eastside Syracuse, Syracuse, NY
Property Type

Industrial
For Sale Contact for pricing

Property size 67,277 SF
View Details
Whitlock Building

476 South Salina Street, Downtown Syracuse, Syracuse, NY
Space Type

Office
For Lease Contact for pricing

1 space available / 6,261 SF
View Details
Hurbson Building

215 Fayette Street West, Downtown Syracuse, Syracuse, NY
Space Type

Office
For Lease

$14.50/SF/YR
1 space available / 4,000 SF
View Details
Regional Transportation Center

131 NBT Bank Parkway, Lakefront, Syracuse, NY
Space Type

Retail
For Lease Contact for pricing

1 space available / 1,451 SF
View Details
380 Spencer Street

380 Spencer St, Lakefront, Syracuse, NY
Property Type

VacantLand
For Sale Contact for pricing

Property size 2.68 Acre
View Details

Frequently Asked Questions

Here is a rundown of the primary commercial real estate property types currently available in Syracuse:
- Office Space: The market includes 3,866,848 square feet of office spaces in addition to 93 coworking locations.
- Retail Space: Between malls, restaurants and stores, Syracuse is home to 570,319 square feet of available retail space.
- Industrial Space: Warehouses, distribution centers, manufacturing facilities and other industrial types total 489,452 square feet of available space in Syracuse.
The average rent for commercial real estate in Syracuse is $16.79 per square foot. However, specific rates may vary widely by property type, class and quality. The cheapest commercial space in Syracuse costs $5, while the city’s premium locations ask up to $30.
Here is a breakdown of the average size of different property classes (also known as asset class or property type):
- Class A/A+ properties have an average size of 230,291 square feet.
- Class B properties are sized 55,703 square feet, on average.
- Class C properties span an average of 13,678 square feet.
The best area for commercial real estate in Syracuse will depend greatly on your needs. The neighborhood with the largest overall number of commercial listings is Downtown Syracuse, home to no fewer than 60 listings for space of all types. If you're looking for office space, Downtown Syracuse has the highest concentration of office listings at 46.

Meanwhile, Southwest Syracuse has the highest number of industrial availabilities (3), while Downtown Syracuse boasts the largest number of retail listings in the city (11).
CommercialCafe’s CRE offering in Syracuse is enabled by a network of 71 active brokers from 37 different firms, ensuring a wide variety of listings. Working with an experienced professional can make a real difference. Learn more about the benefits of working with a broker.

To get in touch with a broker, use the "Contact Property" button on this search page or fill in the contact form provided on each individual property’s listing page.
The profitability of a commercial real estate investment depends on a multitude of factors working together. These factors include the quality of the asset itself, local market conditions, the state of the local economy and the demand for that particular type of commercial property, to name a few.

Asking rents in the city can be as high as $30 per square foot. In particular, the property type commanding the highest lease rates in Syracuse is Retail space.
The average size of a commercial property here stands at 9,522. However, different asset classes and zoning laws will result in vastly different property sizes. Here is a breakdown of the average size of different commercial asset classes in Syracuse:
Office properties:
- Average size: 54,463 square feet.
- Largest property: Space Available (180,000 square feet).
Retail properties:
- Average size: 15,843 square feet.
- Largest property: Full Building (8,320 square feet).
Industrial properties:
- Average size: 30,591 square feet.

Syracuse, NY Commercial Space Listings

Commercial Space for Lease - Breakdown

The 100 listings for commercial real estate currently available for rent in Syracuse add up to 1,087,134 square feet across various property types. Here's a breakdown of the available space by category:

Property Type	Count of Listings	Total Sq. Ft.
Office	62	893,496
Retail	23	66,883
Industrial	10	117,233
Other	5	9,522

Office properties:

The market has 62 active office listings, encompassing 893,496 square feet.
Syracuse office spaces currently listed on CommercialCafe represent 62% of the total commercial real estate market in Syracuse, compared to an average of 39% across all markets tracked by CommercialCafe.

Retail Space:

There are 23 retail listings available, adding up to a total of 66,883 square feet.
Retail spaces account for approximately 23% of the local commercial market, while the average share taken up by retail in all U.S. markets is 34%.

Industrial Space:

The industrial market in Syracuse offers 10 listings, amounting to 117,233 available square feet.
Industrial spaces, including warehouses and manufacturing sites, make up about 10% of the total commercial space available in the market, compared to a nationwide average of 25%.

The data presented in this section was last updated as of September 10, 2026

Commercial Space for Sale - Breakdown

There are currently 56 properties listed for sale in the Syracuse market, adding up to 1,053,303 square feet of space available for purchase. Here is a breakdown of the commercial space for sale listed locally:

12 office properties
18 retail properties
7 industrial properties

The data presented in this section was last updated as of September 10, 2026

Property Type	Count of Listings	Total Sq. Ft.
Office	12	436,474
Retail	18	132,271
Industrial	7	329,996
Other	19	154,562

Syracuse, NY Commercial Real Estate for Lease and Sale

2407 Valley Drive

1001 Genesee St W N

1401 Erie Blvd East

Whitlock Building

Hurbson Building

Regional Transportation Center

380 Spencer Street

Frequently Asked Questions

Syracuse, NY Commercial Space Listings

Commercial Space for Lease - Breakdown

Commercial Space for Sale - Breakdown

Other Popular Searches

Popular Coworking Searches

Popular Office Searches

Popular Retail Searches

Popular Industrial Searches