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Clemson, SC Commercial Real Estate for Lease and Sale

Explore 9 listing(s) of commercial real estate in Clemson, SC and 7 nearby to find the best space for your business.

CRE Market FAQs

Grandmarc Clemson

125 Anderson Highway, Clemson, SC
Space Type

Retail
For Lease

$25.00/SF/YR
3 spaces available / 2,053 - 3,946 SF
View Details
1353 Tiger Blvd

1353 Tiger Blvd, Clemson, SC
Space Type

Retail
For Lease Contact for pricing

1 space available / 1,500 SF
View Details
106 EARLE ST, CLEMSON, 29631-1521

106 Earle Street, Clemson, SC
Space Type

Office
For Lease

$28.80/SF/YR
1 space available / 1,000 SF
View Details
3 Office Suite- Clemson- 1,642 SQ FT

501 Forest Lane, Clemson, SC
Space Type

Office
For Lease

$18.00/SF/YR
1 space available / 1,642 SF
View Details
106 Earle St

106 Earle St, Clemson, SC
Space Type

Office
For Lease

$28.80/SF/YR
1 space available / 3,721 SF
View Details
3 Office Suite- Clemson- 1,642 SQ FT

501 Forest Lane, Clemson, SC
Space Type

Office
For Lease

$18.00/SF/YR
1 space available / 10,400 SF
View Details
The Pier

West Cherry Road, Clemson, SC
Property Type

VacantLand
For Sale Contact for pricing

Property size 50.5 Acre
View Details
Gateway Village

1390 Tiger Blvd, Clemson, SC
Space Type

Retail
For Lease Contact for pricing

2 spaces available / 1,200 - 1,233 SF
View Details
Browse 7 listing(s) within 10 miles of Clemson, SC
2,400 SQ FT Bldg- Central, Near Clemson

1728 Old Central Road, Central, SC
Space Type

Industrial
For Lease

$9.00/SF/YR
1 space available / 2,889 SF
View Details
6551 U.S. 76

6551 U.S. 76, Pendleton, SC
Property Type

VacantLand
For Sale

$895,000
View Details
Two Historic Retail Spaces in Downtown Pendleton

102 & 104 Exchange St, Pendleton, SC
Space Type

Retail
For Lease Contact for pricing

1 space available / 1,700 SF
View Details
FULLY LEASED - 4 New Construction Townhomes

804 S Mechanic St, Pendleton, SC
Property Type

Multi-Family
For Sale

$750,000
Built in 2023 / Property size 5,280 SF
View Details
7700 Highway 76

7700 U.S. 76, Pendleton, SC
Property Type

VacantLand
For Sale

$2,600,000
View Details
1298 Eighteen Mile Road

1298 Eighteen Mile Rd, Central, SC
Property Type

VacantLand
For Sale

$399,999
View Details
1467 Eighteen Mile Road Central, SC

1467 18 Mile Road, Central, SC
Property Type

VacantLand
For Sale

Subject To Offer
View Details

Frequently Asked Questions

CommercialCafe’s CRE offering in Clemson is enabled by a network of 7 active brokers from 7 different firms, ensuring a wide variety of listings. Working with an experienced professional can make a real difference. Learn more about the benefits of working with a broker.

To get in touch with a broker, use the "Contact Property" button on this search page or fill in the contact form provided on each individual property’s listing page.
The profitability of a commercial real estate investment depends on a multitude of factors working together. These factors include the quality of the asset itself, local market conditions, the state of the local economy and the demand for that particular type of commercial property, to name a few.

Clemson, SC Commercial Space Listings

Commercial Space for Lease - Breakdown

The 7 listings for commercial real estate currently available for rent in Clemson add up to 30,086 square feet across various property types. Here's a breakdown of the available space by category:

Property Type	Count of Listings	Total Sq. Ft.
Office	4	16,763
Retail	3	13,323

Office properties:

The market has 4 active office listings, encompassing 16,763 square feet.
Clemson office spaces currently listed on CommercialCafe represent 57% of the total commercial real estate market in Clemson, compared to an average of 53% across all markets tracked by CommercialCafe.

Retail Space:

There are 3 retail listings available, adding up to a total of 13,323 square feet.
Retail spaces account for approximately 42% of the local commercial market, while the average share taken up by retail in all U.S. markets is 46%.

The data presented in this section was last updated as of September 10, 2026

Commercial Space for Sale - Breakdown

There are currently 2 properties listed for sale in the Clemson market, adding up to 3,774 square feet of space available for purchase. Here is a breakdown of the commercial space for sale listed locally:

1 retail property

The data presented in this section was last updated as of September 10, 2026

Property Type	Count of Listings	Total Sq. Ft.
Retail	1	3,723
Other	1	51

Clemson, SC Commercial Real Estate for Lease and Sale

Grandmarc Clemson

1353 Tiger Blvd

106 EARLE ST, CLEMSON, 29631-1521

3 Office Suite- Clemson- 1,642 SQ FT

106 Earle St

3 Office Suite- Clemson- 1,642 SQ FT

The Pier

Gateway Village

Browse 7 listing(s) within 10 miles of Clemson, SC

2,400 SQ FT Bldg- Central, Near Clemson

6551 U.S. 76

Two Historic Retail Spaces in Downtown Pendleton

FULLY LEASED - 4 New Construction Townhomes

7700 Highway 76

1298 Eighteen Mile Road

1467 Eighteen Mile Road Central, SC

Frequently Asked Questions

Clemson, SC Commercial Space Listings

Commercial Space for Lease - Breakdown

Commercial Space for Sale - Breakdown

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