Uptown Manhattan, Manhattan, NY Office Spaces for Rent

Find the best Uptown Manhattan, Manhattan, NY office space among 86 for rent listings currently on the market.

161 Dyckman Street

161 Dyckman Street, Inwood, Stamford, NY
Property Type

Office
For Lease Contact for pricing

2 spaces available / 3,760 - 6,270 SF
View Details (opens in new window)
512 W 181st St

512 W 181st St, Washington Heights, New York, NY
Property Type

Office
For Lease Contact for pricing

4 spaces available / 5,000 - 5,473 SF
View Details (opens in new window)
1970 Adam Clayton Powell Jr. Blvd

1970 Adam Clayton Powell Jr. Blvd, Harlem, New York, NY
Property Type

Office
For Lease Contact for pricing

1 space available / 2,500 SF
View Details (opens in new window)
230 East 106th Street

230 East 106th Street, East Harlem, New York, NY
Property Type

Office
For Lease Contact for pricing

3 spaces available / 3,671 - 8,906 SF
View Details (opens in new window)
345 West 145th Street

345 West 145th Street, Harlem, New York, NY
Property Type

Retail
For Lease Contact for pricing

3 spaces available / 1,248 - 8,698 SF
View Details (opens in new window)
Urban League Empowerment Center

121 West 125th Street, Harlem, New York, NY
Property Type

Office
For Lease Contact for pricing

1 space available / 38,000 SF
View Details (opens in new window)
68 East 131st Street

68 East 131st Street, East Harlem, New York, NY
Property Type

Multi-Family
For Lease

$2,976.00/MO
1 space available / 830 SF
View Details (opens in new window)

Uptown Manhattan, Manhattan, NY Office Inventory Breakdown

There are a number of factors that make a city attractive for businesses to relocate or expand, as well as for investors to enhance their portfolios through local acquisitions. Among the most important factors to consider are the size and quality of the local office market, which is an essential component of the local economy.

Total Office Space in Manhattan: 5,494,733 Sq. Ft.

In 2025 the Manhattan office market encompassed 5,494,733 square feet of space. Out of that total, 604,557 square feet were in office properties sized between 500,000 and 1,000,000 square feet. Meanwhile, 1,028,088 square feet were in office buildings sized between 50,000 and 100,000 square feet.
Class A office space makes up a 20.71% share of Manhattan office inventory, while Class B office assets represent roughly 43.54% of the market total.

Manhattan Office Market Breakdown by Building Size
Building Size Range	Total Square Feet	Share of Total Office
50k to 100k Sq. Ft.	1,028,088 Sq. Ft.	18.71%
100k to 500k Sq. Ft.	2,893,861 Sq. Ft.	52.67%
500k to 1M Sq. Ft.	604,557 Sq. Ft.	11%

Manhattan Office Market Breakdown by Building Quality Rating
Class	Total Square Feet	Share of Total Office
Class A	1,138,157 Sq. Ft.	20.71%
Class B	2,392,457 Sq. Ft.	43.54%
Class C	1,908,054 Sq. Ft.	34.73%

Data was provided by CommercialEdge, refers to properties larger than 50,000 square feet.

About us

CommercialCafe is your go-to commercial real estate listing source. We partner with highly respected major brokerages from across the country to ensure high-quality listings that are updated frequently. Our online marketplace lists all commercial property types from office, coworking, retail, and industrial to special purpose properties.

CommercialCafe is a trusted Yardi brand and is an integral part of the CommercialEdge network — the fastest-growing network of online real estate marketplaces, which ranks on the 1st page of Google for all top markets, attracts more than 2 million monthly visits, and generates more than 350,000 broker contacts.

Uptown Manhattan, Manhattan, NY Office Spaces for Rent

161 Dyckman Street

512 W 181st St

1970 Adam Clayton Powell Jr. Blvd

230 East 106th Street

345 West 145th Street

Urban League Empowerment Center

68 East 131st Street

Uptown Manhattan, Manhattan, NY Office Inventory Breakdown

Total Office Space in Manhattan: 5,494,733 Sq. Ft.

Other Popular Searches

Popular Coworking Searches

Popular Commercial Searches

About us

About Us

Our Tools