- For Lease Contact for pricing
- Property Type Office - Medical Office
- Property Size 107,199 SF
- Lot Size 5.11 Acre
- # of Floors 4
- Property Tenancy Multi-Tenant
- Building Class A
- Year Built 1999
- Year Renovated 2021
- Date Updated Mar 29, 2026
Description
Located in the prestigious Irvine Spectrum submarket, Pacifica Medical Plaza offers healthcare providers an exceptional opportunity to establish or expand their practice in one of Orange County’s most sought-after medical office destinations. This distinguished four-story, 114,209-square-foot building delivers a high-image environment designed to meet the expectations of today’s discerning medical tenants and their patients alike.
Benefiting from Irvine Spectrum’s affluent and growing demographics, the property draws a strong and diverse patient base from across the broader Orange County region. Patients consistently seek out this location for access to high-quality medical care, making Pacifica Medical Plaza an ideal setting for providers looking to build a thriving, long-term practice in a premier Southern California healthcare market.
PROMINENT LOCATION & ACCESSIBILITY
The site’s prominent location has high visibility from SR-133 and Irvine Center Drive to create a strong brand image in a proven successful medical market with high growth. Excellent accessibility from 3 major thoroughfares:
• Laguna Freeway (SR-133)
• Santa Ana Freeway (I-5)
• San Diego Freeway (I-405)
MARKET & HOSPITAL PROXIMITY
• The location is able to conveniently serve over 890,000 patients and is growing (within a 15 minute drive time) due to the quality of the roads, major thoroughfares and accessibility of the site
• The service area is expected to grow at a rate of 4% per year
BUILDING HIGHLIGHTS
• Efficient, large open floor plates able to accommodate many specialized medical uses
• Potential to deliver HCAI compliant ground floor
• Full floor opportunity available
• Ground floor availability
HOSPITAL PROXIMITY
• Tenants will find value in the proximity to Hoag Hospital Irvine and Kaiser Permanente Orange County-Irvine Medical Center, located less than 2 miles away. City of Hope’s $1-billion cancer hospital and research center in Irvine is also less than 3 miles away and scheduled for completion in 2025
RECENT RENOVATIONS
• Major capital improvements have been completed including common areas, landscaping, and a new parking structure. New energy efficient systems to keep operating expenses low
• Ownership is committed to enhancing the standard patient and provider experience to create a unique, tranquil building. More upgrades to come!
AMPLE PARKING
• 5.6/1000 parking ratio with both surface and covered parking in the new 3-level garage. Reserved physician parking
• Reserved physician parking
SIGNAGE OPPORTUNITIES
• Eyebrow and monument signages are available with certain suite requirements and restrictions
True
7 Spaces Available
Suite
Medical Office
Contact for pricing
2,598 SF
1
Immediate
No
120
Suite 120 (120/130 are contiguous to 12,631 RSF)
• Space Available: 6,815 SF
• Lease Rate: Call broker for details
• Lease Type: Call broker for details
• Suite Description: Shell space ready for tenant customization.
Suite
Medical Office
Contact for pricing
2,043 SF
2
5,986 SF
Immediate
No
240
Suite 240 (Contiguous up to 5,986 RSF)
• Space Available: 2,043 SF
• Lease Rate: Call broker for details
• Lease Type: Call broker for details
• Suite Description: Shell space ready for tenant customization.
Suite
Medical Office
Contact for pricing
3,943 SF
2
5,986 SF
Immediate
No
250
Suite 250 (Contiguous up to 5,986 RSF)
• Space Available: 3,943 SF
• Lease Rate: Call broker for details
• Lease Type: Call broker for details
• Suite Description: Shell space ready for tenant customization.
Suite
Medical Office
Contact for pricing
4,213 SF
3
Immediate
No
360
Suite 360
• Space Available: 4,213 SF
• Lease Rate: Call broker for details
• Lease Type: Call broker for details
• Suite Description: Shell space ready for tenant customization.
Suite
Medical Office
Contact for pricing
5,944 SF
4
13,562 SF
Immediate
No
400
Suite 400 (Contiguous up to 13,562 RSF)
• Space Available: 5,944 SF
• Lease Rate: Call broker for details
• Lease Type: Call broker for details
• Suite Description: Shell space ready for tenant customization.
Contacts
MedWest Realty
MedWest Realty
MedWest Realty