Gateway Crossing - 201 & 225 Gateway Blvd

225 Gateway Blvd, South San Francisco, CA 94080

Property Information

  • For Lease Contact for pricing
  • Property Type Office - Life Sciences
  • Property Size 106,076 SF
  • Lot Size 2.44 Acre
  • Parking Spaces Avail. 339
  • Parking Ratio 3.20 / 1,000 SF
  • Property Tenancy Multi-Tenant
  • Building Class B
  • Year Built 1998
  • Date Updated May 19, 2026

Description

Gateway Crossing at 201 & 225 Gateway Blvd is a 106,076-square-foot Class B office property situated on a 2.44-acre lot. The site offers ample parking with 339 spaces and a parking ratio of 3.2 spaces per 1,000 square feet. Built in 1998, the property is designed to meet the needs of businesses seeking functionality and convenience. With its strategic layout and on-site parking, this office location provides a seamless environment for employees and visitors alike.

Positioned in the Gateway neighborhood, the property benefits from proximity to a wealth of nearby amenities. Comfort Inn & Suites, Embassy Suites by Hilton, and Hampton Inn are all within 0.2 miles, offering convenient options for business travelers. Dining choices such as HL Peninsula Restaurant, Dumpling Empire, and Cafe Bunn Mi are within 0.3 miles, providing quick access to local cuisine. Nearby fuel stations like Golden Gate Gasoline and EV charging options further enhance the area's accessibility. San Francisco International Airport is approximately 2.8 miles away, offering easy connectivity for out-of-town clients and staff.

4 Spaces Available

201 Gateway Blvd 2nd Floor

Space Type

Life Sciences

Lease Rate

Contact for pricing

Total Space

26,553 SF

Floor

2

Divisible Space

26,553 - 26,553 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

• Biology Lab • Tissue culture suites • House Gases: • Vac, CDA, He, N2 • Large conference rooms • Private offices • Open office area

225 Gateway Blvd 1st Floor

Space Type

Life Sciences

Lease Rate

Contact for pricing

Total Space

16,732 SF

Floor

1

Divisible Space

16,732 - 16,732 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

Lab area includes:

• Biology labs

• Lab support

• Tissue culture suites

• (2) Two fume hoods

• House gases:

• Vac, CDA, & Co2  Office area includes:

• Private offices

• Open office area

225 Gateway Blvd 1st Floor

Space Type

Flex - Office

Lease Rate

Contact for pricing

Total Space

16,421 SF

Floor

1

Divisible Space

16,421 - 16,421 SF

Available Date

60 Days

Renewal Option

No

Sublease

Yes

Sublease Expiry

Dec 31, 2030

Turnkey

Yes

Partial 1st Floor

Full 2nd floor

Plug and play office space

Biology and Chemistry labs

Vivarium

Access to common lobby and

shipping & receiving

5 minute walk to South San

Francisco Caltrain station

Walking distance to amenities

225 Gateway Blvd 2nd Floor

Space Type

Flex - Office

Lease Rate

Contact for pricing

Total Space

36,217 SF

Floor

2

Divisible Space

36,217 - 36,217 SF

Available Date

60 Days

Renewal Option

No

Sublease

Yes

Sublease Expiry

Dec 31, 2030

Partial 1st Floor

Full 2nd floor

Plug and play office space

Biology and Chemistry labs

Vivarium

Access to common lobby and

shipping & receiving

5 minute walk to South San

Francisco Caltrain station

Walking distance to amenities

Contacts

Richard Friday

CBRE

Christopher R. Jacobs

CBRE

Location

Located at 225 Gateway Blvd, South San Francisco, CA 94080, this property is part of the Gateway neighborhood and San Francisco market.

Contact Gateway Crossing - 201 & 225 Gateway Blvd
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