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Office Space for Rent in South San Francisco, CA - 101 Listings

  • Britannia Modular Labs II - South San Francisco
    333 Allerton Avenue, The East Side, South San Francisco, CA 94080
    Contact for pricing
    Property
    • Office
    Availability
    • 2 Spaces
    • 39,927 Sqft
  • 11, 21, 31 & 61 Airport Blvd - South San Francisco
    21 Airport Blvd, Lindenville, South San Francisco, CA 94080
    Contact for pricing
    Property
    • Office
    Availability
    • 3 Spaces
    • 3,028 Sqft
  • Britannia Biotech Gateway Center II - South San Francisco
    225 Gateway Blvd, Gateway, South San Francisco, CA 94080
    Contact for pricing
    Property
    • Office
    Availability
    • 1 Space
    • 16,577 Sqft
  • Britannia Biotech Gateway Center I - 2 Corporate Drive - South San Francisco
    2 Corporate Drive, Gateway, South San Francisco, CA 94080
    Contact for pricing
    Property
    • Office
    Availability
    • 1 Space
    • 36,000 Sqft
  • Britannia Biotech Gateway Center I - 1 Corporate Drive - South San Francisco
    1 Corporate Drive, Gateway, South San Francisco, CA 94080
    Contact for pricing
    Property
    • Office
    Availability
    • 1 Space
    • 36,000 Sqft
  • 681 Gateway Blvd - South San Francisco
    681 Gateway Blvd, Gateway, South San Francisco, CA 94080
    Contact for pricing
    Property
    • Office
    Availability
    • 2 Spaces
    • 65,914 Sqft
  • 6000 Shoreline Court - South San Francisco
    6000 Shoreline Court, Paradise Valley, South San Francisco, CA 94080
    Contact for pricing
    Property
    • Office
    Availability
    • 2 Spaces
    • 9,608 Sqft
  • 701 Gateway - S San Francisco
    701 Gateway Blvd, Gateway, S San Francisco, CA 94080
    For Lease $39/Sqft/Year
    Property
    • Office
    Availability
    • 1 Space
    • 4,293 Sqft
  • Britannia Pointe Grand - South San Francisco
    250 East Grand Avenue, The East Side, South San Francisco, CA 94080
    Contact for pricing
    Property
    • Office
    Availability
    • 1 Space
    • 23,000 Sqft
  • Edgewater Business Park - South San Francisco
    260 Littlefield Avenue, The East Side, South San Francisco, CA 94080
    Contact for pricing
    Property
    • Office
    Availability
    • 1 Space
    • 14,943 Sqft
  • The Gateway Technology Center - 630 Gateway Blvd - South San Francisco
    630 Gateway Blvd, The East Side, South San Francisco, CA 94080
    For Lease $63/Sqft/Year
    Property
    • Office
    Availability
    • 1 Space
    • 50,160 Sqft
  • The Gateway Technology Center - 650 Gateway Blvd - South San Francisco
    650 Gateway Blvd, The East Side, South San Francisco, CA 94080
    For Lease $63/Sqft/Year
    Property
    • Office
    Availability
    • 1 Space
    • 50,400 Sqft
  • The Gateway Technology Center - 600 Gateway Blvd - South San Francisco
    600 Gateway Blvd, The East Side, South San Francisco, CA 94080
    For Lease $63/Sqft/Year
    Property
    • Office
    Availability
    • 1 Space
    • 50,400 Sqft
  • The Cove at Oyster Point III - South San Francisco
    151 Oyster Point Blvd, Oyster Point, South San Francisco, CA 94080
    Contact for pricing
    Property
    • Office
    Availability
    • 1 Space
    • 15,241 Sqft
  • Genesis - South Tower - South San Francisco
    1 Tower Place, Paradise Valley, South San Francisco, CA 94080
    Contact for pricing
    Property
    • Office
    Availability
    • 3 Spaces
    • 87,067 Sqft
  • Genesis - North Tower - South San Francisco
    2 Tower Place, Paradise Valley, South San Francisco, CA 94080
    Contact for pricing
    Property
    • Office
    Availability
    • 7 Spaces
    • 137,737 Sqft
  • South San Francisco Business Center - South San Francisco
    800 Dubuque Avenue, Gateway, South San Francisco, CA 94080
    Contact for pricing
    Property
    • Office
    Availability
    • 1 Space
    • 5,741 Sqft
  • 2400 Westborough Blvd - South San Francisco
    2400 Westborough Blvd, North Westborough, South San Francisco, CA 94080
    For Lease $33 - $42/Sqft/Year
    Property
    • Office
    Availability
    • 2 Spaces
    • 2,182 Sqft
  • 100-130 Produce Avenue - South San Francisco
    100 Produce Avenue, Lindenville, South San Francisco, CA 94080
    Contact for pricing
    Property
    • Office
    Availability
    • 5 Spaces
    • 9,105 Sqft
  • Spruce Avenue II - South San Francisco
    90 South Spruce Avenue, Orange Park, South San Francisco, CA 94080
    For Lease $13.2 - $33/Sqft/Year
    Property
    • Office
    Availability
    • 6 Spaces
    • 8,382 Sqft
  • Oyster Point Marina Plaza I - S San Francisco
    400 Oyster Point Blvd, Oyster Point, S San Francisco, CA 94080
    For Lease $42/Sqft/Year
    Property
    • Office
    Availability
    • 10 Spaces
    • 17,227 Sqft
  • Gateway Commons - S San Francisco
    651 Gateway Blvd, Gateway, S San Francisco, CA 94080
    For Lease $45/Sqft/Year
    Property
    • Office
    Availability
    • 5 Spaces
    • 92,660 Sqft
  • Gateway Commons - S San Francisco
    611 Gateway Blvd, Gateway, S San Francisco, CA 94080
    For Lease $45/Sqft/Year
    Property
    • Office
    Availability
    • 3 Spaces
    • 52,000 Sqft
  • Oyster Point Marina Plaza II - S San Francisco
    395 Oyster Point Blvd, Oyster Point, S San Francisco, CA 94080
    For Lease $42/Sqft/Year
    Property
    • Office
    Availability
    • 6 Spaces
    • 46,461 Sqft
  • Gateway Commons - S San Francisco
    601 Gateway Blvd, Gateway, S San Francisco, CA 94080
    For Lease $45/Sqft/Year
    Property
    • Office
    Availability
    • 10 Spaces
    • 131,670 Sqft

South San Francisco, CA Commercial Inventory Breakdown

Office Spaces

Total: 18,549,022 SF

Data provided by Yardi Matrix, properties over 50k SF, includes office with retail

By square footage range:

  • 50k to 100k SF: 2,054,232 SF / 11.07% of total office
  • 100k to 500k SF: 10,575,980 SF / 57.02% of total office
  • 500k to 1M SF: 1,286,500 SF / 6.94% of total office
  • > 1M SF: 4,632,310 SF / 24.97% of total office

By class:

  • Class A: 10,660,618 SF / 57.47% of total office
  • Class B: 3,944,380 SF / 21.26% of total office

Top 10 Largest Office Buildings

in South San Francisco

Office building Address Sqft Year built
Southline NEC Tanforan Avenue & South Maple Avenue, 94080 2,000,000 n/a
Genentech Headquarters - Lower Main Campus 1 DNA Way, 94080 1,562,310 1970
Kilroy Oyster Point - Phase II 389 Oyster Point Blvd, 94080 1,070,000 n/a
Kilroy Oyster Point - Phase I 389 Oyster Point Blvd, 94080 656,000 2021
Britannia Pointe Grand 250 East Grand Avenue, 94080 630,500 1989
Genesis - North Tower 2 Tower Place, 94080 381,523 2018
Gateway of Pacific - Building 1000A 1000 Gateway Blvd, 94080 350,000 2021
Gateway of Pacific - Phase III 700 Gateway Blvd, 94080 350,000 2022
Genesis - South Tower 1 Tower Place, 94080 324,986 2009
The Merck Campus 221 East Grand Avenue, 94080 294,000 2019

Most Recently-Built Office Buildings

in South San Francisco

Office building Address Sqft Year built
The Merck Campus 221 East Grand Avenue, 94080 294,000 2019
279 East Grand Avenue 279 East Grand Avenue, 94080 211,405 2019
The Cove at Oyster Point VII 131 Oyster Point Blvd, 94080 175,830 2019
Britannia East Grand: Genentech Headquarters - South Campus - Building 40 500 East Grand Avenue, 94080 160,582 2019
The Cove at Oyster Point VI 161 Oyster Point Blvd, 94080 148,020 2019
Genesis - North Tower 2 Tower Place, 94080 381,523 2018
The Cove at Oyster Point I 111 Oyster Point Blvd, 94080 115,697 2017
The Cove at Oyster Point II 121 Oyster Point Blvd, 94080 102,737 2017
The Cove at Oyster Point III 151 Oyster Point Blvd, 94080 153,047 2016
The Cove at Oyster Point IV 171 Oyster Point Blvd, 94080 140,053 2016

South San Francisco Demographics

Population

  • Total Population67,120
  • Male Population(49.8 %) 33,420
  • Female Population(50.2 %) 33,700
  • Median Age39.10

Income/Financial

  • Average Household Income$110,853
  • Median Household Income$92,074
  • Median Income Under 25$81,250
  • Median Income 25-44$96,065
  • Median Income 45-64$112,548
  • Median Income Over 65$54,424