South San Francisco Office Market Trends

Office Rental Market

  • $64.92 2019 Avg. Asking Rent
  • 9.75 % 2019 Avg. Vacancy Rate
  • 989,837 2019 Office Completions (Sqft)
  • 1,755,519 2020 Estimated Pipeline (Sqft)
In 2019, the average asking rent for office space in South San Francisco was $64.92 per square foot, and the office vacancy rate across the market averaged 9.75 %. During 2019, developers added 989,837 square feet of new office space to the South San Francisco market inventory. Office developments estimated for delivery during 2020 total 1,755,519 square feet.

Average Office Asking Rents by Class

2019 Average Office Rent per Square Foot

  • South San Francisco Class A Office Buildings$57.97
  • South San Francisco Class B Office Buildings$43.03
  • CA Class A Office Buildings$51.59
  • CA Class B Office Buildings$34.34
  • CA Class C Office Buildings$22.62

South San Francisco, CA Office Asking Rents by Class

OFFICE CONSTRUCTION IN South San Francisco, CA

  • South San Francisco, CA Total Sqft completed in 2019 989,837
  • South San Francisco, CA Total Sqft under construction in 2020 1,755,519
10 Largest Office Buildings in South San Francisco
Building name Address Total Sqft Year built
Genentech Headquarters - Lower Main Campus 1 DNA Way, 94080 1,408,361 1970
Kilroy Oyster Point - Phase I 379 Oyster Point Blvd, 94080 656,000 2021
Gateway of Pacific I 1000 Gateway Blvd, 94080 510,000 2021
Gateway of Pacific II 750 Gateway Blvd, 94080 440,000 2021
Genesis - North Tower 2 Tower Place, 94080 381,523 2018
Gateway of Pacific III 700 Gateway Blvd, 94080 360,000 2021
201 Haskins Way 201 Haskins Way, 94080 311,369 2021
The Merck Campus 221 East Grand Avenue, 94080 294,000 2019
Genentech Headquarters - Mid Main Campus - Buildings 13-15 340 Point San Bruno Blvd, 94080 277,814 2003
Genentech Headquarters - Mid Main Campus - Buildings 10-12 & 36 99 DNA Way, 94080 276,044 1975
Largest Office Properties Recently Completed in South San Francisco
Office building Address Sqft Completed
Kilroy Oyster Point - Phase I 379 Oyster Point Blvd, 94080 656,000 2021
Gateway of Pacific I 1000 Gateway Blvd, 94080 510,000 2021
Gateway of Pacific II 750 Gateway Blvd, 94080 440,000 2021
Gateway of Pacific III 700 Gateway Blvd, 94080 360,000 2021
201 Haskins Way 201 Haskins Way, 94080 311,369 2021
The Cove at Oyster Point V 181 Oyster Point Blvd, 94080 164,150 2020
The Merck Campus 221 East Grand Avenue, 94080 294,000 2019
279 East Grand Avenue 279 East Grand Avenue, 94080 211,405 2019
The Cove at Oyster Point VII 131 Oyster Point Blvd, 94080 175,830 2019
Britannia East Grand: Genentech Headquarters - South Campus - Building 40 500 East Grand Avenue, 94080 160,582 2019
Data provided by Commercial Edge

Office Spaces for Rent in California

See trends for nearby markets

The South San Francisco office market contains an inventory of 12,715,680 square feet of office space, in 131 buildings that are equal to or larger than 25,000 square feet.

This market trends report is based on analysis of city-level data. Averages were calculated based on values dated January 1st 2019 through December 31st 2019. Construction pipeline data shown is valid as of April 2020. The information on this page was compiled using data provided by our sister company, CommercialEdge – a market intelligence solution which offers comprehensive knowledge on all South San Francisco commercial properties sized 25,000 square feet or larger.

While every effort was made to ensure the accuracy of the data presented in this report, the information is provided “as is” and neither CommercialCafe nor CommercialEdge can guarantee that the information provided is complete.