Britannia Oyster Point II - Building A

333 Oyster Point Blvd, South San Francisco, CA 94080

Property Information

  • For Lease Contact for pricing
  • Property Type Office - Life Sciences
  • Property Size 121,760 SF
  • Lot Size 8.84 Acre
  • Parking Spaces Avail. 340
  • Parking Ratio 2.80 / 1,000 SF
  • Property Tenancy Multi-Tenant
  • Building Class A
  • Year Built 2008
  • Date Updated Apr 21, 2026

Description

Britannia Oyster Point II - Building A is a Class A office property featuring 121,760 square feet of space on an expansive 8.84-acre lot. The building includes 340 parking spaces with a parking ratio of 2.8, ensuring convenience for tenants and visitors alike. Built in 2008, this contemporary office building offers a professional environment tailored for businesses seeking quality office accommodations in South San Francisco’s Oyster Point area.

The Oyster Point neighborhood provides tenants with proximity to several key amenities. Hotels such as Sonesta ES Suites and AC Hotel are within 0.5 miles, offering nearby options for lodging. Dining choices like HL Peninsula Restaurant and Amoura are just under 1 mile away, while Blink EV charging stations are approximately 0.1 miles from the property. San Francisco International Airport, located about 3 miles away, adds accessibility for business travelers. With various transportation hubs, restaurants, and lodging nearby, this location supports both professional and lifestyle needs.

5 Spaces Available

1st Floor

Space Type

Life Sciences

Lease Rate

Contact for pricing

Total Space

30,769 SF

Floor

1

Divisible Space

30,769 - 30,769 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

2nd Floor

Space Type

Life Sciences

Lease Rate

Contact for pricing

Total Space

30,668 SF

Floor

2

Divisible Space

30,668 - 30,668 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

333 Oyster Point Blvd 2nd Floor

Space Type

Life Sciences

Lease Rate

Contact for pricing

Total Space

30,140 SF

Additional Space Type

Flex - Office

Floor

2

Divisible Space

10,248 - 30,140 SF

Available Date

30 Days

Renewal Option

No

Sublease

Yes

Life Sciences

Flexible sublease in a Class A building • Break Room / Kitchen • Top of the line, AV equipped conference rooms • Private Offices • Mix of Biology and Tissue Culture • Easy Access to Highway 101 • Accessibility to numerous amenities within walking distance • Ample parking with EV car charging stalls

3rd Floor

Space Type

Life Sciences

Lease Rate

Contact for pricing

Total Space

32,169 SF

Floor

3

Divisible Space

32,169 - 32,169 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

4th Floor

Space Type

Life Sciences

Lease Rate

Contact for pricing

Total Space

32,169 SF

Floor

4

Divisible Space

32,169 - 32,169 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

Contacts

Christopher R. Jacobs

CBRE

Richard Friday

CBRE

Location

Located at 333 Oyster Point Blvd, South San Francisco, CA 94080, this property is part of the Oyster Point neighborhood and San Francisco market.

Contact Britannia Oyster Point II - Building A
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