Britannia Oyster Point II - Building B

331 Oyster Point Blvd, South San Francisco, CA 94080

Property Information

  • For Lease Contact for pricing
  • Property Type Office - Life Sciences
  • Property Size 128,751 SF
  • Lot Size 8.84 Acre
  • Parking Spaces Avail. 360
  • Parking Ratio 2.80 / 1,000 SF
  • Property Tenancy Multi-Tenant
  • Building Class A
  • Year Built 2008
  • Date Updated Aug 13, 2026

Description

Britannia Oyster Point II–Building B is a Class A life sciences building at 331 Oyster Point Boulevard in South San Francisco's Oyster Point submarket, totaling 128,751 square feet. Completed in 2008, the property provides 360 parking spaces at a ratio of 2.8 per 1,000 square feet on an 8.84-acre site. Oyster Point is a peninsula on San Francisco Bay at the eastern edge of South San Francisco, connected to US-101 via the Oyster Point Boulevard interchange and positioned within the densest concentration of biotechnology firms on the San Francisco Peninsula.

3 Spaces Available

331 Oyster Point Boulevard 1st Floor

Space Type

Life Sciences

Lease Rate

Contact for pricing

Total Space

30,000 SF

Floor

1

Max Contiguous

60,000 SF

Available Date

Immediate

Renewal Option

No

Sublease

Yes

Turnkey

No

331 Oyster Point Boulevard 2nd Floor

Space Type

Life Sciences

Lease Rate

Contact for pricing

Total Space

33,333 SF

Floor

2

Divisible Space

33,333 - 33,333 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

Build Type

Shell

Turnkey

No

Life science warm shell ready for tenant improvements 

331 Oyster Point Boulevard 3rd Floor

Space Type

Life Sciences

Lease Rate

Contact for pricing

Total Space

30,000 SF

Floor

2

Max Contiguous

60,000 SF

Available Date

Immediate

Renewal Option

No

Sublease

Yes

Turnkey

No

2 7 Private Offices 1 1 Conference Rooms 9 0 Cubes 

Contacts

Location

Located at 331 Oyster Point Blvd, South San Francisco, CA 94080, this property is part of the Oyster Point neighborhood and San Francisco market.

Contact Britannia Oyster Point II - Building B
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