The Frame Building

541 West 21st Street, New York, NY 10011

  • For Lease Contact for pricing
  • Property Type Office - Creative Office
  • Property Size 67,000 SF
  • Lot Size 0.17 Acre
  • Property Tenancy Multi-Tenant
  • Building Class B
  • Year Built 1915
  • Date Updated May 28, 2025

The Frame Building is a 67,000-square-foot creative office property situated on a compact 0.17-acre lot at 541 West 21st Street. Built in 1915, this Class B building combines historic charm with functionality, offering a distinctive workspace for businesses seeking a Chelsea location. Its design suits creative industries, fostering collaboration and innovation in a thriving business hub.

Nestled in the vibrant Chelsea neighborhood, this property enjoys proximity to diverse amenities and transportation options. Popular eateries like Empire Diner and New York Burger Co. are within a 0.2-mile radius, while Moynihan Train Hall and 34th Street–Hudson Yards subway station are approximately 0.6 miles away, providing convenient transit access. Nearby hotels, including The High Line Hotel and Dream Downtown, are less than 0.4 miles away, adding convenience for visiting colleagues or clients. Chelsea’s cultural and educational institutions, such as the Fashion Institute of Technology, further enhance the appeal of this dynamic location.

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Spaces Available

Contacts

broker
Joseph Sipala Is this you?

Jones Lang LaSalle

broker
Zachary A. Weil Is this you?

Newmark

broker
CJ Heitner Is this you?

Newmark

broker
Brett Stein Is this you?

Newmark

broker
Cole Gendels Is this you?

Newmark

Location

Getting Around

  • Walk Score ®

    94/100 Walker's Paradise

  • Transit Score ®

    100/100 Rider's Paradise

  • Bike Score ®

    93/100 Biker's Paradise
Powered by Walk Score ®
  • City New York, NY
  • Neighborhood Chelsea
  • Zip Code 10011
  • Market Manhattan

Points of Interest

  • 34th Street–Hudson Yards

    0.64 miles

  • Moynihan Train Hall

    0.66 miles

  • 28th Street

    0.71 miles

  • No. 2 Penn Plaza Entrance

    0.81 miles

  • 7th Avenue & 33rd Street at Northwest Corner

    0.84 miles

  • 33rd St / 7th Av

    0.87 miles

  • 33rd Street

    0.95 miles

  • 34th Street & Broadway at Northwest Corner

    1.00 miles

  • Broadway & 23rd Street at Northeast Corner

    1.03 miles

  • Broadway & 23rd Street at Southeast Corner

    1.03 miles

  • Mobil

    0.61 miles

  • Blink

    0.65 miles

  • ChargePoint

    0.71 miles

  • BP

    1.90 miles

  • Citgo

    2.96 miles

  • Gulf

    3.01 miles

  • Sunoco

    3.27 miles

  • MPG Manhattan Parking: MP Hudson

    0.45 miles

  • MPG Parking Javits Center

    0.63 miles

  • Vincent 15 Parking LLC

    0.82 miles

  • Lot 9

    0.84 miles

  • Icon Parking

    0.85 miles

  • Lot 10

    0.88 miles

  • City Parking

    1.01 miles

  • SP+

    1.05 miles

  • Icon

    1.14 miles

  • iClean

    2.90 miles

  • The High Line Hotel

    0.14 miles

  • Selina Chelsea New York City

    0.28 miles

  • Maritime Hotel

    0.39 miles

  • Liberty Inn

    0.39 miles

  • The Leo House

    0.39 miles

  • Dream Downtown

    0.40 miles

  • Colonial House

    0.40 miles

  • The GEM Hotel Chelsea

    0.44 miles

  • The Standard

    0.46 miles

  • Soho House New York

    0.47 miles

  • Bateaux New York

    0.09 miles

  • Pepe Giallo

    0.11 miles

  • Empire Diner

    0.14 miles

  • New York Burger Co

    0.15 miles

  • The Mermaid Inn – Chelsea

    0.15 miles

  • The Red Cat

    0.15 miles

  • Moran's

    0.16 miles

  • Chelsea Square Market

    0.20 miles

  • 10th Avenue Pizza & Cafe

    0.22 miles

  • Artichoke Basille's Pizza

    0.23 miles

  • Guardian Angel School

    0.11 miles

  • General Theological Seminary

    0.19 miles

  • Avenues

    0.23 miles

  • Public School 33

    0.37 miles

  • Middle School 260

    0.40 miles

  • Public School 11

    0.40 miles

  • New York City Museum School

    0.42 miles

  • New York City Laboratory School for Collaborative Studies

    0.42 miles

  • New York City Laboratory Middle School for Collaborative Studies

    0.42 miles

  • Corlears School

    0.51 miles

  • San Jose Nursery

    0.21 miles

  • Star A Kidz

    1.10 miles

  • Downing Street Playgroup

    1.22 miles

  • Alpha Bet Preschool of Murray Hill

    1.37 miles

  • Push My Swing

    1.38 miles

  • NY Kids Club

    1.42 miles

  • Wee Ones Club

    1.45 miles

  • Kindercare

    1.46 miles

  • Samuel J. Heyman Early Childhood Center

    1.50 miles

  • Explore + Discover Early Learning Center

    1.54 miles

Frequently Asked Questions

What type of office space is available to lease at The Frame Building?

In total, there is 13,034 square feet of office space for lease here. Availability at this location includes 2 Retail spaces. The property offers Multi-Tenant commercial space.

Is The Frame Building suitable for a small business?

Yes, availabilities here may be suitable for small businesses with 1 office space under 5,000 square feet available.

Does The Frame Building have parking?
Parking information for the property isn't currently listed. However, other nearby parking options include MPG Manhattan Parking: MP Hudson, located 0.45 miles away, and MPG Parking Javits Center, which is 0.63 miles away.
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