The Frame Building

541 West 21st Street, New York, NY 10011

Property Information

  • For Lease Contact for pricing
  • Property Type Office - Creative Office
  • Property Size 67,000 SF
  • Lot Size 0.17 Acre
  • Property Tenancy Multi-Tenant
  • Building Class B
  • Year Built 1915
  • Date Updated May 4, 2026

Description

The Frame Building is a 67,000-square-foot creative office property situated on a compact 0.17-acre lot at 541 West 21st Street. Built in 1915, this Class B building combines historic charm with functionality, offering a distinctive workspace for businesses seeking a Chelsea location. Its design suits creative industries, fostering collaboration and innovation in a thriving business hub.

Nestled in the vibrant Chelsea neighborhood, this property enjoys proximity to diverse amenities and transportation options. Popular eateries like Empire Diner and New York Burger Co. are within a 0.2-mile radius, while Moynihan Train Hall and 34th Street–Hudson Yards subway station are approximately 0.6 miles away, providing convenient transit access. Nearby hotels, including The High Line Hotel and Dream Downtown, are less than 0.4 miles away, adding convenience for visiting colleagues or clients. Chelsea’s cultural and educational institutions, such as the Fashion Institute of Technology, further enhance the appeal of this dynamic location.

2 Spaces Available

2nd Floor

Space Type

Retail

Lease Rate

Contact for pricing

Total Space

8,034 SF

Floor

2

Divisible Space

8,034 - 8,034 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

Ground Floor

Space Type

Retail

Lease Rate

Contact for pricing

Total Space

5,000 SF

Divisible Space

5,000 - 5,000 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

Contacts

Joseph Sipala

Jones Lang LaSalle

Zachary A. Weil

Newmark

CJ Heitner

Newmark

Brett Stein

Newmark

Cole Gendels

Newmark

Location

Located at 541 West 21st Street, New York, NY 10011, this property is part of the Chelsea neighborhood and Manhattan market.

Contact The Frame Building
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