Lee County, FL Commercial Real Estate for Lease and Sale
Explore 770 listing(s) of commercial real estate in Lee County, FL to find the best space for your business.
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1760-1910 NE Pine Island Road, Hancock, Cape Coral, FL -
NWC Pine Island Rd & Chiquita Blvd, Mariner, Cape Coral, FL -
14555 Global Pkwy, Southwest Florida Airport, Fort Myers, FLProperty Type- VacantLand
For Sale- $1,744,140
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24600/602 S Tamiami Trl, Bonita Springs, FLSpace Type- Office
For Lease- $7,900.00/MO
1 space available / 4,000 SF -

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122 Chiquita Boulevard South, Mariner, Cape Coral, FLSpace Type
- Office
For Lease- $35.00 - $40.00/SF/YR
2 spaces available / 1,014 SF -
15881 S Tamiami Trl, Estero Bay Park, Fort Myers, FLSpace Type- Retail
For Lease- $18.00/SF/YR
1 space available / 2,962 SF -
7899 Drew Circle, San Carlos Park, Fort Myers, FLSpace Type- Industrial
For Lease- $15.00/SF/YR
1 space available / 27,990 SF -
1925 - 1929 Skyline Blvd, Trafalgar, Cape Coral, FLSpace Type- Retail
For Lease- $35.00/SF/YR
2 spaces available / 3,042 SF -
3526 Work Dr, Winkler, Fort Myers, FL -
13158 Saddle Rd, Southwest Florida Airport, Fort Myers, FLProperty Type- VacantLand
For Sale- $17,760,000
Property size 1,014,512 SF -
4401 Skates Circle, Buckingham, Fort Myers, FLProperty Type- Land
For Sale- $1,390,880
Property size 19.87 Acre -
5515 Emerson Square Boulevard, Estero Bay Park, Fort Myers, FLProperty Type- VacantLand
For Sale- $1,690,000
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3507 Lee Blvd, Lehigh Acres, FLSpace Type- Office
For Lease- $22.00/SF/YR
1 space available / 1,361 SF -
10060 Amberwood Rd, Southwest Florida Airport, Fort Myers, FLSpace Type- Industrial
For Lease- $17.50/SF/YR
1 space available / 2,500 SF -
3800 Colonial Blvd, Omni - Heritage Palms, Fort Myers, FLSpace Type- Office
For Lease- $18.00/SF/YR
1 space available / 1,775 SF -
16100 Lee Rd, Fiddlesticks, Fort Myers, FL -
17061 - 17091 Alico Center Rd, San Carlos Park, Fort Myers, FL -
706 SW Pine Island Rd, Trafalgar, Cape Coral, FLSpace Type- Retail
For Lease- $40.00/SF/YR
1 space available / 1,544 SF -
2853 - 2861 Work Drive, Dunbar, Fort Myers, FL -
1314-1322 Lafayette St, Caloosahatchee, Cape Coral, FL
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11803 Metro Pkwy, Villas, Fort Myers, FLSpace Type- Industrial
For Lease- $8.50/SF/YR
1 space available / 51,194 SF -
5893 Enterprise Pkwy, Buckingham, Fort Myers, FLProperty Type- Industrial
For Sale- $4,800,000
Built in 1995 / Property size 20,000 SF -
24520 Production Circle, Bonita Springs, FLSpace Type- Office
For Lease- $16.48/SF/YR
1 space available / 1,603 SF -
2121 W 1st St, Sunset - Edison, Fort Myers, FLSpace Type- Office
For Lease- $4.54/SF/YR
2 spaces available / 140 - 196 SF -
11600 Adelmo Lane, Villas, Fort Myers, FLSpace Type- Office, Industrial
For Lease- $12.50 - $27.27/SF/YR
2 spaces available / 1,100 - 30,000 SF -
1120, 1122, 1130 & 1138 Main St, San Carlos Island, Fort Myers Beach, FLProperty Type- VacantLand
For Sale- $6,200,000
Built in 1963 / Property size 4,038 SF -
3264 Cleveland Ave, Sunset - Edison, Fort Myers, FLProperty Type- Other
For Sale- $795,000
Built in 1958 / Property size 1,440 SF -
2570 CHAMPION RING RD, Forum, Fort Myers, FLProperty Type- VacantLand
For Sale- $3,137,000
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4511 N Key Dr, North Fort Myers, FLProperty Type- VacantLand
For Sale- Call for Offers
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8417 Littleton Rd, Palmona Park, North Fort Myers, FLSpace Type- Industrial
For Lease- $12.50/SF/YR
1 space available / 4,800 SF -
17050 Alico Commerce Ct Ste 2, San Carlos Park, Fort Myers, FLSpace Type- Industrial
For Lease- $18.00/SF/YR
1 space available / 2,000 SF -
9490 Corkscrew Rd, Estero Town Center, Estero, FLProperty Type- VacantLand
For Sale- $1,971,000
Built in 2000 / Property size 2,491 SF -
4824 Cape Coral St, Caloosahatchee, Cape Coral, FL -
2189 N Tamiami Trail, Palmona Park, North Fort Myers, FLProperty Type- VacantLand
For Sale- Call For Details
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3133 4th St W, Lehigh Acres, FLProperty Type- VacantLand
For Sale- $395,000
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1520 Royal Palm Square Blvd, Palm Lee, Fort Myers, FLSpace Type- Office
For Lease- $12.00/SF/YR
1 space available / 3,541 SF -
3949 Evans Avenue #404, Winkler, Fort Myers, FLSpace Type
- Office
For Lease- $12.00/SF/YR
1 space available / 1,400 SF -
1109/1119 Del Prado Boulevard S, Hancock, Cape Coral, FLSpace Type- Retail
For Lease- $25.00/SF/YR
1 space available / 960 SF -
3350 Woods Edge Circle, Bonita Springs, FLSpace Type- Office
For Lease- $30.00/SF/YR
1 space available / 1,035 SF -
12126 S Cleveland Ave, Villas, Fort Myers, FL -
17030 Alico Commerce Court #313, San Carlos Park, Fort Myers, FLProperty Type- Industrial
For Sale- $375,000
Property size 1,250 SF -
3760 Fowler St, Winkler, Fort Myers, FLProperty Type- Industrial
For Sale- Call for Pricing
Built in 1972 / Property size 49,092 SF -
5592 Lee St, Lehigh Acres, FLSpace Type- Industrial
For Lease- $10.00/SF/YR
1 space available / 4,796 SF -
13630 Goldenwood Drive, Southwest Florida Airport, Fort Myers, FL -
15991 N Cleveland Ave, North Fort Myers, FL -
22770 S Tamiami Trl, Fountain Lakes, Estero, FLProperty Type- Land
For Sale- $2,150,000
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San Carlos & Kelly Road, Iona, Fort Myers, FLProperty Type- VacantLand
For Sale- $4,150,000
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925 East Industrial Circle, Hancock, Cape Coral, FLSpace Type- Industrial
For Lease- $16.50/SF/YR
2 spaces available / 9,616 - 9,691 SF -
1215 SE 10 ST, Hancock, Cape Coral, FLProperty Type- Industrial
For Sale- $3,000,000
Built in 1979 / Property size 12,023 SF -
10200 Metro Pkwy, Winkler, Fort Myers, FLProperty Type- VacantLand
For Sale- $3,750,000
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16200 Ben Hill Griffin Pkwy, Southwest Florida Airport, Fort Myers, FL -
2915 Estero Boulevard, Fort Myers Beach, FLProperty Type- VacantLand
For Sale- $1,095,000
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3560 Veronica S Shoemaker Blvd, Eastwood Village, Fort Myers, FLSpace Type- Industrial
For Lease- $32,000.00/MO
1 space available / 17,190 SF